SIRT1 Activation by Small Molecules: KINETIC AND BIOPHYSICAL EVIDENCE FOR DIRECT INTERACTION OF ENZYME AND ACTIVATOR

por Dai, Han, Kustigian, Lauren, Carney, David, Case, April, Considine, Thomas, Hubbard, Basil P., Perni, Robert B., Riera, Thomas V., Szczepankiewicz, Bruce, Vlasuk, George P., Stein, Ross L.
Publicado 2010

Small-Molecule Activators of Insulin-Degrading Enzyme Discovered through High-Throughput Compound Screening

por Cabrol, Christelle, Huzarska, Malwina A., Dinolfo, Christopher, Rodriguez, Maria C., Reinstatler, Lael, Ni, Jake, Yeh, Li-An, Cuny, Gregory D., Stein, Ross L., Selkoe, Dennis J., Leissring, Malcolm A.
Publicado 2009

SARS-CoV-2 spike protein induces endothelial inflammation via ACE2 independently of viral replication

por Montezano, Augusto C., Camargo, Livia L., Mary, Sheon, Neves, Karla B, Rios, Francisco J, Stein, Ross, Lopes, Rheure A., Beattie, Wendy, Thomson, Jacqueline, Herder, Vanessa, Szemiel, Agnieszka M., McFarlane, Steven, Palmarini, Massimo, Touyz, Rhian M.
Publicado 2023

Designed Inhibitors of Insulin-Degrading Enzyme Regulate the Catabolism and Activity of Insulin

por Leissring, Malcolm A., Malito, Enrico, Hedouin, Sabrine, Reinstatler, Lael, Sahara, Tomoko, Abdul-Hay, Samer O., Choudhry, Shakeel, Maharvi, Ghulam M., Fauq, Abdul H., Huzarska, Malwina, May, Philip S., Choi, Sungwoon, Logan, Todd P., Turk, Benjamin E., Cantley, Lewis C., Manolopoulou, Marika, Tang, Wei-Jen, Stein, Ross L., Cuny, Gregory D., Selkoe, Dennis J.
Publicado 2010