Identification of Guide-Intrinsic Determinants of Cas9 Specificity

por Huston, Nicholas C., Tycko, Josh, Tillotson, Eric L., Wilson, Christopher J., Myer, Vic E., Jayaram, Hariharan, Steinberg, Barrett E.
Publicado 2019

SMOOT libraries and phage-induced directed evolution of Cas9 to engineer reduced off-target activity

por Cerchione, Derek, Loveluck, Katherine, Tillotson, Eric L., Harbinski, Fred, DaSilva, Jen, Kelley, Chase P., Keston-Smith, Elise, Fernandez, Cecilia A., Myer, Vic E., Jayaram, Hariharan, Steinberg, Barrett E.
Publicado 2020