Novel strategies for the mitigation of cytokine release syndrome induced by T cell engaging therapies with a focus on the use of kinase inhibitors

por Leclercq, Gabrielle, Steinhoff, Nathalie, Haegel, Hélène, De Marco, Donata, Bacac, Marina, Klein, Christian
Publicado 2022

Dissecting the mechanism of cytokine release induced by T-cell engagers highlights the contribution of neutrophils

por Leclercq, Gabrielle, Servera, Llucia Alberti, Danilin, Sabrina, Challier, John, Steinhoff, Nathalie, Bossen, Claudia, Odermatt, Alex, Nicolini, Valeria, Umaña, Pablo, Klein, Christian, Bacac, Marina, Giusti, Anna-Maria, Schneider, Anneliese, Haegel, Hélène
Publicado 2022

Combination of T-Cell Bispecific Antibodies With PD-L1 Checkpoint Inhibition Elicits Superior Anti-Tumor Activity

por Sam, Johannes, Colombetti, Sara, Fauti, Tanja, Roller, Andreas, Biehl, Marlene, Fahrni, Linda, Nicolini, Valeria, Perro, Mario, Nayak, Tapan, Bommer, Esther, Schoenle, Anne, Karagianni, Maria, Le Clech, Marine, Steinhoff, Nathalie, Klein, Christian, Umaña, Pablo, Bacac, Marina
Publicado 2020

Corrigendum: Combination of T-Cell Bispecific Antibodies With PD-L1 Checkpoint Inhibition Elicits Superior Anti-Tumor Activity

por Sam, Johannes, Colombetti, Sara, Fauti, Tanja, Roller, Andreas, Biehl, Marlene, Fahrni, Linda, Nicolini, Valeria, Perro, Mario, Nayak, Tapan, Bommer, Esther, Schoenle, Anne, Karagianni, Maria, Le Clech, Marine, Steinhoff, Nathalie, Klein, Christian, Umaña, Pablo, Bacac, Marina
Publicado 2021

JAK and mTOR inhibitors prevent cytokine release while retaining T cell bispecific antibody in vivo efficacy

por Leclercq, Gabrielle, Haegel, Hélène, Toso, Alberto, Zimmermann, Tina, Green, Luke, Steinhoff, Nathalie, Sam, Johannes, Pulko, Vesna, Schneider, Anneliese, Giusti, Anna Maria, Challier, John, Freimoser-Grundschober, Anne, Larivière, Laurent, Odermatt, Alex, Stern, Martin, Umana, Pablo, Bacac, Marina, Klein, Christian
Publicado 2022

Dissecting the Mechanisms Underlying the Cytokine Release Syndrome (CRS) Mediated by T-Cell Bispecific Antibodies

por Leclercq-Cohen, Gabrielle, Steinhoff, Nathalie, Albertí Servera, Llucia, Nassiri, Sina, Danilin, Sabrina, Piccione, Emily, Yángüez, Emilio, Hüsser, Tamara, Herter, Sylvia, Schmeing, Stephan, Gerber, Petra, Schwalie, Petra, Sam, Johannes, Briner, Stefanie, Jenni, Sylvia, Bianchi, Roberta, Biehl, Marlene, Cremasco, Floriana, Apostolopoulou, Katerina, Haegel, Hélène, Klein, Christian, Umaña, Pablo, Bacac, Marina
Publicado 2023