Igf1r Signaling Is Indispensable for Preimplantation Development and Is Activated via a Novel Function of E-cadherin

por Bedzhov, Ivan, Liszewska, Ewa, Kanzler, Benoît, Stemmler, Marc P.
Publicado 2012

Dynamic EMT: a multi‐tool for tumor progression

por Brabletz, Simone, Schuhwerk, Harald, Brabletz, Thomas, Stemmler, Marc P.
Publicado 2021

Editorial: Translational Insights Into Pancreatic Ductal Adenocarcinoma

por Bijlsma, Maarten F., Bailey, Peter J., Stemmler, Marc P.
Publicado 2022

Deregulation of Transcription Factor Networks Driving Cell Plasticity and Metastasis in Pancreatic Cancer

por van Roey, Ruthger, Brabletz, Thomas, Stemmler, Marc P., Armstark, Isabell
Publicado 2021

Inappropriate cadherin switching in the mouse epiblast compromises proper signaling between the epiblast and the extraembryonic ectoderm during gastrulation

por Basilicata, M. Felicia, Frank, Marcus, Solter, Davor, Brabletz, Thomas, Stemmler, Marc P.
Publicado 2016

The EMT-activator ZEB1 induces bone metastasis associated genes including BMP-inhibitors

por Mock, Kerstin, Preca, Bogdan-Tiberius, Brummer, Tilman, Brabletz, Simone, Stemmler, Marc P., Brabletz, Thomas
Publicado 2015

The ZEB1/miR-200c feedback loop regulates invasion via actin interacting proteins MYLK and TKS5

por Sundararajan, Vignesh, Gengenbacher, Nicolas, Stemmler, Marc P., Kleemann, Julia A., Brabletz, Thomas, Brabletz, Simone
Publicado 2015

The Epithelial Cell Adhesion Molecule EpCAM Is Required for Epithelial Morphogenesis and Integrity during Zebrafish Epiboly and Skin Development

por Slanchev, Krasimir, Carney, Thomas J., Stemmler, Marc P., Koschorz, Birgit, Amsterdam, Adam, Schwarz, Heinz, Hammerschmidt, Matthias
Publicado 2009

The Transcription Factor Elf3 Is Essential for a Successful Mesenchymal to Epithelial Transition

por Sengez, Burcu, Aygün, Ilkin, Shehwana, Huma, Toyran, Neslihan, Tercan Avci, Sanem, Konu, Ozlen, Stemmler, Marc P., Alotaibi, Hani
Publicado 2019

ZEB1 turns into a transcriptional activator by interacting with YAP1 in aggressive cancer types

por Lehmann, Waltraut, Mossmann, Dirk, Kleemann, Julia, Mock, Kerstin, Meisinger, Chris, Brummer, Tilman, Herr, Ricarda, Brabletz, Simone, Stemmler, Marc P., Brabletz, Thomas
Publicado 2016

Pancreas morphogenesis and homeostasis depends on tightly regulated Zeb1 levels in epithelial cells

por Lasierra Losada, María, Pauler, Melissa, Vandamme, Niels, Goossens, Steven, Berx, Geert, Leppkes, Moritz, Schuhwerk, Harald, Brabletz, Simone, Brabletz, Thomas, Stemmler, Marc P.
Publicado 2021

The transcription factor ZEB1 regulates stem cell self-renewal and cell fate in the adult hippocampus

por Gupta, Bhavana, Errington, Adam C., Jimenez-Pascual, Ana, Eftychidis, Vasileios, Brabletz, Simone, Stemmler, Marc P., Brabletz, Thomas, Petrik, David, Siebzehnrubl, Florian A.
Publicado 2021

Interconnected feedback loops among ESRP1, HAS2, and CD44 regulate epithelial-mesenchymal plasticity in cancer

por Jolly, Mohit Kumar, Preca, Bogdan-Tiberius, Tripathi, Satyendra C., Jia, Dongya, George, Jason T., Hanash, Samir M., Brabletz, Thomas, Stemmler, Marc P., Maurer, Jochen, Levine, Herbert
Publicado 2018

N-cadherin stabilises neural identity by dampening anti-neural signals

por Punovuori, Karolina, Migueles, Rosa P., Malaguti, Mattias, Blin, Guillaume, Macleod, Kenneth G., Carragher, Neil O., Pieters, Tim, van Roy, Frans, Stemmler, Marc P., Lowell, Sally
Publicado 2019

A novel ZEB1/HAS2 positive feedback loop promotes EMT in breast cancer

por Preca, Bogdan-Tiberius, Bajdak, Karolina, Mock, Kerstin, Lehmann, Waltraut, Sundararajan, Vignesh, Bronsert, Peter, Matzge-Ogi, Alexandra, Orian-Rousseau, Véronique, Brabletz, Simone, Brabletz, Thomas, Maurer, Jochen, Stemmler, Marc P.
Publicado 2017

Interplay between the EMT transcription factors ZEB1 and ZEB2 regulates hematopoietic stem and progenitor cell differentiation and hematopoietic lineage fidelity

por Wang, Jueqiong, Farkas, Carlos, Benyoucef, Aissa, Carmichael, Catherine, Haigh, Katharina, Wong, Nick, Huylebroeck, Danny, Stemmler, Marc P., Brabletz, Simone, Brabletz, Thomas, Nefzger, Christian M., Goossens, Steven, Berx, Geert, Polo, Jose M., Haigh, Jody J.
Publicado 2021

p120 Catenin-Mediated Stabilization of E-Cadherin Is Essential for Primitive Endoderm Specification

por Pieters, Tim, Goossens, Steven, Haenebalcke, Lieven, Andries, Vanessa, Stryjewska, Agata, De Rycke, Riet, Lemeire, Kelly, Hochepied, Tino, Huylebroeck, Danny, Berx, Geert, Stemmler, Marc P., Wirth, Dagmar, Haigh, Jody J., van Hengel, Jolanda, van Roy, Frans
Publicado 2016

Genome‐wide cooperation of EMT transcription factor ZEB1 with YAP and AP‐1 in breast cancer

por Feldker, Nora, Ferrazzi, Fulvia, Schuhwerk, Harald, Widholz, Sebastian A, Guenther, Kerstin, Frisch, Isabell, Jakob, Kathrin, Kleemann, Julia, Riegel, Dania, Bönisch, Ulrike, Lukassen, Sören, Eccles, Rebecca L, Schmidl, Christian, Stemmler, Marc P, Brabletz, Thomas, Brabletz, Simone
Publicado 2020

Lima1 mediates the pluripotency control of membrane dynamics and cellular metabolism

por Duethorn, Binyamin, Groll, Fabian, Rieger, Bettina, Drexler, Hannes C. A., Brinkmann, Heike, Kremer, Ludmila, Stehling, Martin, Borowski, Marie-Theres, Mildner, Karina, Zeuschner, Dagmar, Zernicka-Goetz, Magdalena, Stemmler, Marc P., Busch, Karin B., Vaquerizas, Juan M., Bedzhov, Ivan
Publicado 2022

Inactivation of Zeb1 in GRHL2-deficient mouse embryos rescues mid-gestation viability and secondary palate closure

por Carpinelli, Marina R., de Vries, Michael E., Auden, Alana, Butt, Tariq, Deng, Zihao, Partridge, Darren D., Miles, Lee B., Georgy, Smitha R., Haigh, Jody J., Darido, Charbel, Brabletz, Simone, Brabletz, Thomas, Stemmler, Marc P., Dworkin, Sebastian, Jane, Stephen M.
Publicado 2020