Modeling of Cell Nuclear Mechanics: Classes, Components, and Applications

por Hobson, Chad M., Stephens, Andrew D.
Publicado 2020

Separate roles for chromatin and lamins in nuclear mechanics

por Stephens, Andrew D., Banigan, Edward J., Marko, John F.
Publicado 2017

Tension-dependent nucleosome remodeling at the pericentromere in yeast

por Verdaasdonk, Jolien S., Gardner, Ryan, Stephens, Andrew D., Yeh, Elaine, Bloom, Kerry
Publicado 2012

Effects of altering histone posttranslational modifications on mitotic chromosome structure and mechanics

por Biggs, Ronald, Liu, Patrick Z., Stephens, Andrew D., Marko, John F.
Publicado 2019

Cohesin, condensin, and the intramolecular centromere loop together generate the mitotic chromatin spring

por Stephens, Andrew D., Haase, Julian, Vicci, Leandra, Taylor, Russell M., Bloom, Kerry
Publicado 2011

A Versatile Micromanipulation Apparatus for Biophysical Assays of the Cell Nucleus

por Currey, Marilena L., Kandula, Viswajit, Biggs, Ronald, Marko, John F., Stephens, Andrew D.
Publicado 2022

The spatial segregation of pericentric cohesin and condensin in the mitotic spindle

por Stephens, Andrew D., Quammen, Cory W., Chang, Binny, Haase, Julian, Taylor, Russell M., Bloom, Kerry
Publicado 2013

Dyskerin, tRNA genes, and condensin tether pericentric chromatin to the spindle axis in mitosis

por Snider, Chloe E., Stephens, Andrew D., Kirkland, Jacob G., Hamdani, Omar, Kamakaka, Rohinton T., Bloom, Kerry
Publicado 2014

Chromatin and lamin A determine two different mechanical response regimes of the cell nucleus

por Stephens, Andrew D., Banigan, Edward J., Adam, Stephen A., Goldman, Robert D., Marko, John F.
Publicado 2017

Correlating nuclear morphology and external force with combined atomic force microscopy and light sheet imaging separates roles of chromatin and lamin A/C in nuclear mechanics

por Hobson, Chad M., Kern, Megan, O’Brien, E. Timothy, Stephens, Andrew D., Falvo, Michael R., Superfine, Richard
Publicado 2020

Individual pericentromeres display coordinated motion and stretching in the yeast spindle

por Stephens, Andrew D., Snider, Chloe E., Haase, Julian, Haggerty, Rachel A., Vasquez, Paula A., Forest, M. Gregory, Bloom, Kerry
Publicado 2013

Liquid chromatin Hi-C characterizes compartment-dependent chromatin interaction dynamics

por Belaghzal, Houda, Borrman, Tyler, Stephens, Andrew D., Lafontaine, Denis L., Venev, Sergey V., Weng, Zhiping, Marko, John F., Dekker, Job
Publicado 2021

Chromatin histone modifications and rigidity affect nuclear morphology independent of lamins

por Stephens, Andrew D., Liu, Patrick Z., Banigan, Edward J., Almassalha, Luay M., Backman, Vadim, Adam, Stephen A., Goldman, Robert D., Marko, John F.
Publicado 2018

High-throughput gene screen reveals modulators of nuclear shape

por Tamashunas, Andrew C., Tocco, Vincent J., Matthews, James, Zhang, Qiao, Atanasova, Kalina R., Paschall, Lauren, Pathak, Shreya, Ratnayake, Ranjala, Stephens, Andrew D., Luesch, Hendrik, Licht, Jonathan D., Lele, Tanmay P.
Publicado 2020

Physicochemical mechanotransduction alters nuclear shape and mechanics via heterochromatin formation

por Stephens, Andrew D., Liu, Patrick Z., Kandula, Viswajit, Chen, Haimei, Almassalha, Luay M., Herman, Cameron, Backman, Vadim, O’Halloran, Thomas, Adam, Stephen A., Goldman, Robert D., Banigan, Edward J., Marko, John F.
Publicado 2019

Pericentric chromatin loops function as a nonlinear spring in mitotic force balance

por Stephens, Andrew D., Haggerty, Rachel A., Vasquez, Paula A., Vicci, Leandra, Snider, Chloe E., Shi, Fu, Quammen, Cory, Mullins, Christopher, Haase, Julian, Taylor, Russell M., Verdaasdonk, Jolien S., Falvo, Michael R., Jin, Yuan, Forest, M. Gregory, Bloom, Kerry
Publicado 2013

Multimodal interference-based imaging of nanoscale structure and macromolecular motion uncovers UV induced cellular paroxysm

por Gladstein, Scott, Almassalha, Luay M., Cherkezyan, Lusik, Chandler, John E., Eshein, Adam, Eid, Aya, Zhang, Di, Wu, Wenli, Bauer, Greta M., Stephens, Andrew D., Morochnik, Simona, Subramanian, Hariharan, Marko, John F., Ameer, Guillermo A., Szleifer, Igal, Backman, Vadim
Publicado 2019

HP1α is a chromatin crosslinker that controls nuclear and mitotic chromosome mechanics

por Strom, Amy R, Biggs, Ronald J, Banigan, Edward J, Wang, Xiaotao, Chiu, Katherine, Herman, Cameron, Collado, Jimena, Yue, Feng, Ritland Politz, Joan C, Tait, Leah J, Scalzo, David, Telling, Agnes, Groudine, Mark, Brangwynne, Clifford P, Marko, John F, Stephens, Andrew D
Publicado 2021

CTCF is essential for proper mitotic spindle structure and anaphase segregation

por Chiu, Katherine, Berrada, Yasmin, Eskndir, Nebiyat, Song, Dasol, Fong, Claire, Naughton, Sarah, Chen, Tina, Moy, Savanna, Gyurmey, Sarah, James, Liam, Ezeiruaku, Chimere, Capistran, Caroline, Lowey, Daniel, Diwanji, Vedang, Peterson, Samantha, Parakh, Harshini, Burgess, Ayanna R., Probert, Cassandra, Zhu, Annie, Anderson, Bryn, Levi, Nehora, Gerlitz, Gabi, Packard, Mary C., Dorfman, Katherine A., Bahiru, Michael Seifu, Stephens, Andrew D.
Publicado 2023