Multiple gene aberrations and breast cancer: lessons from super-responders

por Wheler, Jennifer J., Atkins, Johnique T., Janku, Filip, Moulder, Stacy L., Yelensky, Roman, Stephens, Philip J., Kurzrock, Razelle
Publicado 2015

Loss of function JAK1 mutations occur at high frequency in cancers with microsatellite instability and are suggestive of immune evasion

por Albacker, Lee A., Wu, Jeremy, Smith, Peter, Warmuth, Markus, Stephens, Philip J., Zhu, Ping, Yu, Lihua, Chmielecki, Juliann
Publicado 2017

Genomic landscape of advanced basal cell carcinoma: Implications for precision treatment with targeted and immune therapies

por Goodman, Aaron M., Kato, Shumei, Cohen, Philip R., Boichard, Amélie, Frampton, Garrett, Miller, Vincent, Stephens, Philip J., Daniels, Gregory A., Kurzrock, Razelle
Publicado 2017

Next generation sequencing of exceptional responders with BRAF-mutant melanoma: implications for sensitivity and resistance

por Wheler, Jennifer, Yelensky, Roman, Falchook, Gerald, Kim, Kevin B, Hwu, Patrick, Tsimberidou, Apostolia M, Stephens, Philip J, Hong, David, Cronin, Maureen T, Kurzrock, Razelle
Publicado 2015

Presence of both alterations in FGFR/FGF and PI3K/AKT/mTOR confer improved outcomes for patients with metastatic breast cancer treated with PI3K/AKT/mTOR inhibitors

por Wheler, Jennifer J., Atkins, Johnique T., Janku, Filip, Moulder, Stacy L., Stephens, Philip J., Yelensky, Roman, Valero, Vicente, Miller, Vincent, Kurzrock, Razelle, Meric-Bernstam, Funda
Publicado 2016

Severe nivolumab-induced pneumonitis preceding durable clinical remission in a patient with refractory, metastatic lung squamous cell cancer: a case report

por Li, Hong, Ma, Weijie, Yoneda, Ken Y., Moore, Elizabeth H., Zhang, Yanhong, Pu, Lee L. Q., Frampton, Garrett M., Molmen, Michael, Stephens, Philip J., Li, Tianhong
Publicado 2017

Thymoma Patients Treated in a Phase I Clinic at MD Anderson Cancer Center: Responses to mTOR Inhibitors and Molecular Analyses

por Wheler, Jennifer, Hong, David, Swisher, Stephen G., Falchook, Gerald, Tsimberidou, Apostolia M., Helgason, Thorunn, Naing, Aung, Stephen, Bettzy, Janku, Filip, Stephens, Philip J., Yelensky, Roman, Kurzrock, Razelle
Publicado 2013

Identification and characterization of RET fusions in advanced colorectal cancer

por Le Rolle, Anne-France, Klempner, Samuel J., Garrett, Christopher R., Seery, Tara, Sanford, Eric M., Balasubramanian, Sohail, Ross, Jeffrey S., Stephens, Philip J., Miller, Vincent A., Ali, Siraj M., Chiu, Vi K.
Publicado 2015

Anastrozole and everolimus in advanced gynecologic and breast malignancies: activity and molecular alterations in the PI3K/AKT/mTOR pathway

por Wheler, Jennifer J., Moulder, Stacy L., Naing, Aung, Janku, Filip, Piha-Paul, Sarina A., Falchook, Gerald S., Zinner, Ralph, Tsimberidou, Apostolia M., Fu, Siqing, Hong, David S., Atkins, Johnique T., Yelensky, Roman, Stephens, Philip J., Kurzrock, Razelle
Publicado 2014

Durable clinical benefit to trastuzumab and chemotherapy in a patient with metastatic colon adenocarcinoma harboring ERBB2 amplification

por Disel, Umut, Germain, Alexis, Yilmazel, Bahar, Abali, Huseyin, Bolat, Filiz Aka, Yelensky, Roman, Elvin, Julia A., Lipson, Doron, Chmielecki, Juliann, Wang, Kai, Stephens, Philip J., Ross, Jeffrey S., Miller, Vincent A., Ali, Siraj M., George, Thomas J.
Publicado 2015

Comprehensive Genomic Profiling of Hodgkin Lymphoma Reveals Recurrently Mutated Genes and Increased Mutation Burden

por Liang, Winnie S., Vergilio, Jo‐Anne, Salhia, Bodour, Huang, Helen J., Oki, Yasuhiro, Garrido‐Laguna, Ignacio, Park, Haeseong, Westin, Jason R., Meric‐Bernstam, Funda, Fabrizio, David, Miller, Vincent A., Stephens, Philip J., Fanale, Michelle A., Ross, Jeffrey S., Janku, Filip
Publicado 2018

Relationship of smoking status to genomic profile, chemotherapy response and clinical outcome in patients with advanced urothelial carcinoma

por Joshi, Monika, Vasekar, Monali, Grivas, Petros, Emamekhoo, Hamid, Hsu, JoAnn, Miller, Vincent A., Stephens, Philip J., Ali, Siraj M., Ross, Jeffrey S., Zhu, Junjia, Warrick, Joshua, Drabick, Joseph J., Holder, Sheldon L., Kaag, Matthew, Li, Min, Pal, Sumanta Kumar
Publicado 2016

Targeting HER2 in colorectal cancer: The landscape of amplification and short variant mutations in ERBB2 and ERBB3

por Ross, Jeffrey S., Fakih, Marwan, Ali, Siraj M., Elvin, Julia A., Schrock, Alexa B., Suh, James, Vergilio, Jo‐Anne, Ramkissoon, Shakti, Severson, Eric, Daniel, Sugganth, Fabrizio, David, Frampton, Garrett, Sun, James, Miller, Vincent A., Stephens, Philip J., Gay, Laurie M.
Publicado 2018

The distribution of BRAF gene fusions in solid tumors and response to targeted therapy

por Ross, Jeffrey S., Wang, Kai, Chmielecki, Juliann, Gay, Laurie, Johnson, Adrienne, Chudnovsky, Jacob, Yelensky, Roman, Lipson, Doron, Ali, Siraj M, Elvin, Julia A., Vergilio, Jo‐Anne, Roels, Steven, Miller, Vincent A, Nakamura, Brooke N., Gray, Adam, Wong, Michael K, Stephens, Philip J
Publicado 2016

Targeted genomic landscape of metastases compared to primary tumours in clear cell metastatic renal cell carcinoma

por de Velasco, Guillermo, Wankowicz, Stephanie A., Madison, Russell, Ali, Siraj M., Norton, Craig, Duquette, Audrey, Ross, Jeffrey S., Bossé, Dominick, Lalani, Aly-Khan A., Miller, Vincent A., Stephens, Philip J., Young, Lauren, Hakimi, A. Ari, Signoretti, Sabina, Pal, Sumanta K., Choueiri, Toni K.
Publicado 2018

Distinct age-associated molecular profiles in acute myeloid leukemia defined by comprehensive clinical genomic profiling

por Tarlock, Katherine, Zhong, Shan, He, Yuting, Ries, Rhonda, Severson, Eric, Bailey, Mark, Morley, Samantha, Balasubramanian, Sohail, Erlich, Rachel, Lipson, Doron, Otto, Geoff A., Vergillo, Jo-Anne, Kolb, E. Anders, Ross, Jeffrey S., Mughal, Tariq, Stephens, Philip J., Miller, Vincent, Meshinchi, Soheil, He, Jie
Publicado 2018

Targeted next-generation sequencing of head and neck squamous cell carcinoma identifies novel genetic alterations in HPV+ and HPV- tumors

por Lechner, Matthias, Frampton, Garrett M, Fenton, Tim, Feber, Andrew, Palmer, Gary, Jay, Amrita, Pillay, Nischalan, Forster, Martin, Cronin, Maureen T, Lipson, Doron, Miller, Vincent A, Brennan, Timothy A, Henderson, Stephen, Vaz, Francis, O'Flynn, Paul, Kalavrezos, Nicholas, Yelensky, Roman, Beck, Stephan, Stephens, Philip J, Boshoff, Chris
Publicado 2013

Clinical genomic profiling to identify actionable alterations for investigational therapies in patients with diverse sarcomas

por Groisberg, Roman, Hong, David S., Holla, Vijaykumar, Janku, Filip, Piha-Paul, Sarina, Ravi, Vinod, Benjamin, Robert, Patel, Shreyas Kumar, Somaiah, Neeta, Conley, Anthony, Ali, Siraj M., Schrock, Alexa B., Ross, Jeffrey S., Stephens, Philip J., Miller, Vincent A., Sen, Shiraj, Herzog, Cynthia, Meric-Bernstam, Funda, Subbiah, Vivek
Publicado 2017

A metastatic colon adenocarcinoma harboring BRAF V600E has a durable major response to dabrafenib/trametinib and chemotherapy

por Williams, Casey B, McMahon, Caitlin, Ali, Siraj M, Abramovitz, Mark, Williams, Kirstin A, Klein, Jessica, McKean, Heidi, Yelensky, Roman, George, Thomas J, Elvin, Julia A, Soman, Salil, Lipson, Doron, Chmielecki, Juliann, Morosini, Deborah, Miller, Vincent A, Stephens, Philip J, Ross, Jeffrey S, Leyland-Jones, Brian
Publicado 2015

Molecular profiling of cancer patients enables personalized combination therapy: the I-PREDICT study

por Sicklick, Jason K., Kato, Shumei, Okamura, Ryosuke, Schwaederle, Maria, Hahn, Michael E., Williams, Casey B., De, Pradip, Krie, Amy, Piccioni, David E., Miller, Vincent A., Ross, Jeffrey S., Benson, Adam, Webster, Jennifer, Stephens, Philip J., Lee, J. Jack, Fanta, Paul T., Lippman, Scott M., Leyland-Jones, Brian, Kurzrock, Razelle
Publicado 2019