Nutrient Regulation of Pancreatic Islet β-Cell Secretory Capacity and Insulin Production

por Rohli, Kristen E., Boyer, Cierra K., Blom, Sandra E., Stephens, Samuel B.
Publicado 2022

Synchronized proinsulin trafficking reveals delayed Golgi export accompanies β-cell secretory dysfunction in rodent models of hyperglycemia

por Boyer, Cierra K., Bauchle, Casey J., Zhang, Jianchao, Wang, Yanzhuang, Stephens, Samuel B.
Publicado 2023

The Insulinostatic Effect of Ghrelin Requires MRAP2 Expression in δ Cells

por Yin, Terry C., Bauchle, Casey J., Rouault, Alix A.J., Stephens, Samuel B., Sebag, Julien A.
Publicado 2020

Delayed apoptosis allows islet β-cells to implement an autophagic mechanism to promote cell survival

por Hayes, Heather L., Peterson, Brett S., Haldeman, Jonathan M., Newgard, Christopher B., Hohmeier, Hans E., Stephens, Samuel B.
Publicado 2017

Evaluation of Monoexponential, Stretched‐Exponential and Intravoxel Incoherent Motion MRI Diffusion Models in Early Response Monitoring to Neoadjuvant Chemotherapy in Patients With...

por Almutlaq, Zyad M., Wilson, Daniel J., Bacon, Sarah E., Sharma, Nisha, Stephens, Samuel, Dondo, Tatendashe, Buckley, David L.
Publicado 2022

Identification of a small molecule that stimulates human β-cell proliferation and insulin secretion, and protects against cytotoxic stress in rat insulinoma cells

por Hohmeier, Hans E., Zhang, Lu, Taylor, Brandon, Stephens, Samuel, Lu, Danhong, McNamara, Peter, Laffitte, Bryan, Newgard, Christopher B.
Publicado 2020

SWELL1 is a glucose sensor regulating β-cell excitability and systemic glycaemia

por Kang, Chen, Xie, Litao, Gunasekar, Susheel K., Mishra, Anil, Zhang, Yanhui, Pai, Saachi, Gao, Yiwen, Kumar, Ashutosh, Norris, Andrew W., Stephens, Samuel B., Sah, Rajan
Publicado 2018

ER Redox Homeostasis Regulates Proinsulin Trafficking and Insulin Granule Formation in the Pancreatic Islet β-Cell

por Rohli, Kristen E, Boyer, Cierra K, Bearrows, Shelby C, Moyer, Marshall R, Elison, Weston S, Bauchle, Casey J, Blom, Sandra E, Zhang, Jianchao, Wang, Yanzhuang, Stephens, Samuel B
Publicado 2022

Adipose Triglyceride Lipase Is a Key Lipase for the Mobilization of Lipid Droplets in Human β-Cells and Critical for the Maintenance of Syntaxin 1a Levels in β-Cells

por Liu, Siming, Promes, Joseph A., Harata, Mikako, Mishra, Akansha, Stephens, Samuel B., Taylor, Eric B., Burand, Anthony J., Sivitz, William I., Fink, Brian D., Ankrum, James A., Imai, Yumi
Publicado 2020

A putative long noncoding RNA-encoded micropeptide maintains cellular homeostasis in pancreatic β cells

por Li, Mark, Shao, Fan, Qian, Qingwen, Yu, Wenjie, Zhang, Zeyuan, Chen, Biyi, Su, Dan, Guo, Yuwei, Phan, An-Vi, Song, Long-sheng, Stephens, Samuel B., Sebag, Julien, Imai, Yumi, Yang, Ling, Cao, Huojun
Publicado 2021

RABL6A Promotes Pancreatic Neuroendocrine Tumor Angiogenesis and Progression In Vivo

por Maharjan, Chandra K., Umesalma, Shaikamjad, Kaemmer, Courtney A., Muniz, Viviane P., Bauchle, Casey, Mott, Sarah L., Zamba, K. D., Breheny, Patrick, Leidinger, Mariah R., Darbro, Benjamin W., Stephens, Samuel B., Meyerholz, David K., Quelle, Dawn E.
Publicado 2021

Liquid–liquid phase separation facilitates the biogenesis of secretory storage granules

por Parchure, Anup, Tian, Meng, Stalder, Danièle, Boyer, Cierra K., Bearrows, Shelby C., Rohli, Kristen E., Zhang, Jianchao, Rivera-Molina, Felix, Ramazanov, Bulat R., Mahata, Sushil K., Wang, Yanzhuang, Stephens, Samuel B., Gershlick, David C., von Blume, Julia
Publicado 2022

Utilization of commercial collagens for preparing well-differentiated human beta cells for confocal microscopy

por Brennecke, Brianna R., Yang, USeong, Liu, Siming, Ilerisoy, Fatma S., Ilerisoy, Beyza N., Joglekar, Aditya, Kim, Lucy B., Peachee, Spencer J., Richtsmeier, Syreine L., Stephens, Samuel B., Sander, Edward A., Strack, Stefan, Moninger, Thomas O., Ankrum, James A., Imai, Yumi
Publicado 2023

Perilipin 2 downregulation in β cells impairs insulin secretion under nutritional stress and damages mitochondria

por Mishra, Akansha, Liu, Siming, Promes, Joseph, Harata, Mikako, Sivitz, William, Fink, Brian, Bhardwaj, Gourav, O’Neill, Brian T., Kang, Chen, Sah, Rajan, Strack, Stefan, Stephens, Samuel, King, Timothy, Jackson, Laura, Greenberg, Andrew S., Anokye-Danso, Frederick, Ahima, Rexford S., Ankrum, James, Imai, Yumi
Publicado 2021