Acetylation: a new key to unlock tau’s role in neurodegeneration

por Cook, Casey, Stankowski, Jeannette N, Carlomagno, Yari, Stetler, Caroline, Petrucelli, Leonard
Publicado 2014

Expression of mutant TDP-43 induces neuronal dysfunction in transgenic mice

por Xu, Ya-Fei, Zhang, Yong-Jie, Lin, Wen-Lang, Cao, Xiangkun, Stetler, Caroline, Dickson, Dennis W, Lewis, Jada, Petrucelli, Leonard
Publicado 2011

Acetylation of the KXGS motifs in tau is a critical determinant in modulation of tau aggregation and clearance

por Cook, Casey, Carlomagno, Yari, Gendron, Tania F., Dunmore, Judy, Scheffel, Kristyn, Stetler, Caroline, Davis, Mary, Dickson, Dennis, Jarpe, Matthew, DeTure, Michael, Petrucelli, Leonard
Publicado 2014

Progranulin regulates neuronal outgrowth independent of Sortilin

por Gass, Jennifer, Lee, Wing C, Cook, Casey, Finch, Nicole, Stetler, Caroline, Jansen-West, Karen, Lewis, Jada, Link, Christopher D, Rademakers, Rosa, Nykjær, Anders, Petrucelli, Leonard
Publicado 2012

The Pathological Phenotypes of Human TDP-43 Transgenic Mouse Models Are Independent of Downregulation of Mouse Tdp-43

por Xu, Ya-Fei, Prudencio, Mercedes, Hubbard, Jaime M., Tong, Jimei, Whitelaw, Ena C., Jansen-West, Karen, Stetler, Caroline, Cao, Xiangkun, Song, John, Zhang, Yong-Jie
Publicado 2013

The dual functions of the extreme N-terminus of TDP-43 in regulating its biological activity and inclusion formation

por Zhang, Yong-Jie, Caulfield, Thomas, Xu, Ya-Fei, Gendron, Tania F., Hubbard, Jaime, Stetler, Caroline, Sasaguri, Hiroki, Whitelaw, Ena C., Cai, Shuyi, Lee, Wing Cheung, Petrucelli, Leonard
Publicado 2013

Reduced C9orf72 gene expression in c9FTD/ALS is caused by histone trimethylation, an epigenetic event detectable in blood

por Belzil, Veronique V., Bauer, Peter O., Prudencio, Mercedes, Gendron, Tania F., Stetler, Caroline T., Yan, Irene K., Pregent, Luc, Daughrity, Lillian, Baker, Matthew C., Rademakers, Rosa, Boylan, Kevin, Patel, Tushar C., Dickson, Dennis W., Petrucelli, Leonard
Publicado 2013

Targeted manipulation of the sortilin–progranulin axis rescues progranulin haploinsufficiency

por Lee, Wing C., Almeida, Sandra, Prudencio, Mercedes, Caulfield, Thomas R., Zhang, Yong-Jie, Tay, William M., Bauer, Peter O., Chew, Jeannie, Sasaguri, Hiroki, Jansen-West, Karen R., Gendron, Tania F., Stetler, Caroline T., Finch, NiCole, Mackenzie, Ian R., Rademakers, Rosa, Gao, Fen-Biao, Petrucelli, Leonard
Publicado 2014

Distinct brain transcriptome profiles in C9orf72-associated and sporadic ALS

por Prudencio, Mercedes, Belzil, Veronique V., Batra, Ranjan, Ross, Christian A., Gendron, Tania F., Pregent, Luc J., Murray, Melissa E., Overstreet, Karen K., Piazza-Johnston, Amelia E., Desaro, Pamela, Bieniek, Kevin F., DeTure, Michael, Lee, Wing C., Biendarra, Sherri M., Davis, Mary D., Baker, Matthew C., Perkerson, Ralph B., van Blitterswijk, Marka, Stetler, Caroline T., Rademakers, Rosa, Link, Christopher D., Dickson, Dennis W., Boylan, Kevin B., Li, Hu, Petrucelli, Leonard
Publicado 2015