A secreted MMP is required for reepithelialization during wound healing

por Stevens, Laura J., Page-McCaw, Andrea
Publicado 2012

Evaluation of in vitro antiviral activity of SARS-CoV-2 M(pro) inhibitor pomotrelvir and cross-resistance to nirmatrelvir resistance substitutions

por Tong, Xiao, Keung, Walter, Arnold, Lee D., Stevens, Laura J., Pruijssers, Andrea J., Kook, Seunghyi, Lopatin, Uri, Denison, Mark, Kwong, Ann D.
Publicado 2023

The coronavirus proofreading exoribonuclease mediates extensive viral recombination

por Gribble, Jennifer, Stevens, Laura J., Agostini, Maria L., Anderson-Daniels, Jordan, Chappell, James D., Lu, Xiaotao, Pruijssers, Andrea J., Routh, Andrew L., Denison, Mark R.
Publicado 2021

Detection of the Virulent Form of AVR3a from Phytophthora infestans following Artificial Evolution of Potato Resistance Gene R3a

por Chapman, Sean, Stevens, Laura J., Boevink, Petra C., Engelhardt, Stefan, Alexander, Colin J., Harrower, Brian, Champouret, Nicolas, McGeachy, Kara, Van Weymers, Pauline S. M., Chen, Xinwei, Birch, Paul R. J., Hein, Ingo
Publicado 2014

Structural Definition of a Neutralization-Sensitive Epitope on the MERS-CoV S1-NTD

por Wang, Nianshuang, Rosen, Osnat, Wang, Lingshu, Turner, Hannah L., Stevens, Laura J., Corbett, Kizzmekia S., Bowman, Charles A., Pallesen, Jesper, Shi, Wei, Zhang, Yi, Leung, Kwanyee, Kirchdoerfer, Robert N., Becker, Michelle M., Denison, Mark R., Chappell, James D., Ward, Andrew B., Graham, Barney S., McLellan, Jason S.
Publicado 2019

Mutations in the SARS-CoV-2 RNA dependent RNA polymerase confer resistance to remdesivir by distinct mechanisms

por Stevens, Laura J., Pruijssers, Andrea J., Lee, Hery W., Gordon, Calvin J., Tchesnokov, Egor P., Gribble, Jennifer, George, Amelia S., Hughes, Tia M., Lu, Xiaotao, Li, Jiani, Perry, Jason K., Porter, Danielle P., Cihlar, Tomas, Sheahan, Timothy P., Baric, Ralph S., Götte, Matthias, Denison, Mark R.
Publicado 2022

Stabilized coronavirus spike stem elicits a broadly protective antibody

por Hsieh, Ching-Lin, Werner, Anne P., Leist, Sarah R., Stevens, Laura J., Falconer, Ester, Goldsmith, Jory A., Chou, Chia-Wei, Abiona, Olubukola M., West, Ande, Westendorf, Kathryn, Muthuraman, Krithika, Fritch, Ethan J., Dinnon, Kenneth H., Schäfer, Alexandra, Denison, Mark R., Chappell, James D., Baric, Ralph S., Graham, Barney S., Corbett, Kizzmekia S., McLellan, Jason S.
Publicado 2021

Standardized two-step testing of antibody activity in COVID-19 convalescent plasma

por Gilchuk, Pavlo, Thomsen, Isaac, Yoder, Sandra, Brady, Eric, Chappell, James D., Stevens, Laura J., Denison, Mark R., Sutton, Rachel E., Chen, Rita E., VanBlargan, Laura A., Suryadevara, Naveenchandra, Zost, Seth J., Schmitz, Jonathan, Pulley, Jill M., Diamond, Michael S., Rhoads, Jillian P., Bernard, Gordon R., Self, Wesley H., Rice, Todd W., Wheeler, Allison P., Crowe, James E., Carnahan, Robert H.
Publicado 2021

An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice

por Sheahan, Timothy P., Sims, Amy C., Zhou, Shuntai, Graham, Rachel L., Pruijssers, Andrea J., Agostini, Maria L., Leist, Sarah R., Schäfer, Alexandra, Dinnon, Kenneth H., Stevens, Laura J., Chappell, James D., Lu, Xiaotao, Hughes, Tia M., George, Amelia S., Hill, Collin S., Montgomery, Stephanie A., Brown, Ariane J., Bluemling, Gregory R., Natchus, Michael G., Saindane, Manohar, Kolykhalov, Alexander A., Painter, George, Harcourt, Jennifer, Tamin, Azaibi, Thornburg, Natalie J., Swanstrom, Ronald, Denison, Mark R., Baric, Ralph S.
Publicado 2020

Remdesivir Inhibits SARS-CoV-2 in Human Lung Cells and Chimeric SARS-CoV Expressing the SARS-CoV-2 RNA Polymerase in Mice

por Pruijssers, Andrea J., George, Amelia S., Schäfer, Alexandra, Leist, Sarah R., Gralinksi, Lisa E., Dinnon, Kenneth H., Yount, Boyd L., Agostini, Maria L., Stevens, Laura J., Chappell, James D., Lu, Xiaotao, Hughes, Tia M., Gully, Kendra, Martinez, David R., Brown, Ariane J., Graham, Rachel L., Perry, Jason K., Du Pont, Venice, Pitts, Jared, Ma, Bin, Babusis, Darius, Murakami, Eisuke, Feng, Joy Y., Bilello, John P., Porter, Danielle P., Cihlar, Tomas, Baric, Ralph S., Denison, Mark R., Sheahan, Timothy P.
Publicado 2020

Durability of Responses after SARS-CoV-2 mRNA-1273 Vaccination

por Widge, Alicia T., Rouphael, Nadine G., Jackson, Lisa A., Anderson, Evan J., Roberts, Paul C., Makhene, Mamodikoe, Chappell, James D., Denison, Mark R., Stevens, Laura J., Pruijssers, Andrea J., McDermott, Adrian B., Flach, Britta, Lin, Bob C., Doria-Rose, Nicole A., O’Dell, Sijy, Schmidt, Stephen D., Neuzil, Kathleen M., Bennett, Hamilton, Leav, Brett, Makowski, Mat, Albert, Jim, Cross, Kaitlyn, Edara, Venkata-Viswanadh, Floyd, Katharine, Suthar, Mehul S., Buchanan, Wendy, Luke, Catherine J., Ledgerwood, Julie E., Mascola, John R., Graham, Barney S., Beigel, John H.
Publicado 2020

An mRNA Vaccine against SARS-CoV-2 — Preliminary Report

por Jackson, Lisa A., Anderson, Evan J., Rouphael, Nadine G., Roberts, Paul C., Makhene, Mamodikoe, Coler, Rhea N., McCullough, Michele P., Chappell, James D., Denison, Mark R., Stevens, Laura J., Pruijssers, Andrea J., McDermott, Adrian, Flach, Britta, Doria-Rose, Nicole A., Corbett, Kizzmekia S., Morabito, Kaitlyn M., O’Dell, Sijy, Schmidt, Stephen D., Swanson, Phillip A., Padilla, Marcelino, Mascola, John R., Neuzil, Kathleen M., Bennett, Hamilton, Sun, Wellington, Peters, Etza, Makowski, Mat, Albert, Jim, Cross, Kaitlyn, Buchanan, Wendy, Pikaart-Tautges, Rhonda, Ledgerwood, Julie E., Graham, Barney S., Beigel, John H.
Publicado 2020

Safety and Immunogenicity of SARS-CoV-2 mRNA-1273 Vaccine in Older Adults

por Anderson, Evan J., Rouphael, Nadine G., Widge, Alicia T., Jackson, Lisa A., Roberts, Paul C., Makhene, Mamodikoe, Chappell, James D., Denison, Mark R., Stevens, Laura J., Pruijssers, Andrea J., McDermott, Adrian B., Flach, Britta, Lin, Bob C., Doria-Rose, Nicole A., O’Dell, Sijy, Schmidt, Stephen D., Corbett, Kizzmekia S., Swanson, Phillip A., Padilla, Marcelino, Neuzil, Kathy M., Bennett, Hamilton, Leav, Brett, Makowski, Mat, Albert, Jim, Cross, Kaitlyn, Edara, Venkata Viswanadh, Floyd, Katharine, Suthar, Mehul S., Martinez, David R., Baric, Ralph, Buchanan, Wendy, Luke, Catherine J., Phadke, Varun K., Rostad, Christina A., Ledgerwood, Julie E., Graham, Barney S., Beigel, John H.
Publicado 2020

Neutralizing COVID-19 Convalescent Plasma in Adults Hospitalized With COVID-19: A Blinded, Randomized, Placebo-Controlled Trial

por Self, Wesley H., Wheeler, Allison P., Stewart, Thomas G., Schrager, Harry, Mallada, Jason, Thomas, Christopher B., Cataldo, Vince D., O’Neal, Hollis R., Shapiro, Nathan I., Higgins, Conor, Ginde, Adit A., Chauhan, Lakshmi, Johnson, Nicholas J., Henning, Daniel J., Jaiswal, Stuti J., Mammen, Manoj J., Harris, Estelle S., Pannu, Sonal R., Laguio-Vila, Maryrose, El Atrouni, Wissam, de Wit, Marjolein, Hoda, Daanish, Cohn, Claudia S., McWilliams, Carla, Shanholtz, Carl, Jones, Alan E., Raval, Jay S., Mucha, Simon, Ipe, Tina S., Qiao, Xian, Schrantz, Stephen J., Shenoy, Aarthi, Fremont, Richard D., Brady, Eric J., Carnahan, Robert H., Chappell, James D., Crowe, James E., Denison, Mark R., Gilchuk, Pavlo, Stevens, Laura J., Sutton, Rachel E., Thomsen, Isaac, Yoder, Sandra M., Bistran-Hall, Amanda J., Casey, Jonathan D., Lindsell, Christopher J., Wang, Li, Pulley, Jill M., Rhoads, Jillian P., Bernard, Gordon R., Rice, Todd W.
Publicado 2022

SARS-CoV-2 mRNA Vaccine Design Enabled by Prototype Pathogen Preparedness

por Corbett, Kizzmekia S., Edwards, Darin K., Leist, Sarah R., Abiona, Olubukola M., Boyoglu-Barnum, Seyhan, Gillespie, Rebecca A., Himansu, Sunny, Schäfer, Alexandra, Ziwawo, Cynthia T., DiPiazza, Anthony T., Dinnon, Kenneth H., Elbashir, Sayda M., Shaw, Christine A., Woods, Angela, Fritch, Ethan J., Martinez, David R., Bock, Kevin W., Minai, Mahnaz, Nagata, Bianca M., Hutchinson, Geoffrey B., Wu, Kai, Henry, Carole, Bahi, Kapil, Garcia-Dominguez, Dario, Ma, LingZhi, Renzi, Isabella, Kong, Wing-Pui, Schmidt, Stephen D., Wang, Lingshu, Zhang, Yi, Phung, Emily, Chang, Lauren A., Loomis, Rebecca J., Altaras, Nedim Emil, Narayanan, Elisabeth, Metkar, Mihir, Presnyak, Vlad, Liu, Cuiping, Louder, Mark K., Shi, Wei, Leung, Kwanyee, Yang, Eun Sung, West, Ande, Gully, Kendra L., Stevens, Laura J., Wang, Nianshuang, Wrapp, Daniel, Doria-Rose, Nicole A., Stewart-Jones, Guillaume, Bennett, Hamilton, Alvarado, Gabriela S., Nason, Martha C., Ruckwardt, Tracy J., McLellan, Jason S., Denison, Mark R., Chappell, James D., Moore, Ian N., Morabito, Kaitlyn M., Mascola, John R., Baric, Ralph S., Carfi, Andrea, Graham, Barney S.
Publicado 2020

Durability of mRNA-1273 vaccine–induced antibodies against SARS-CoV-2 variants

por Pegu, Amarendra, O’Connell, Sarah E., Schmidt, Stephen D., O’Dell, Sijy, Talana, Chloe A., Lai, Lilin, Albert, Jim, Anderson, Evan, Bennett, Hamilton, Corbett, Kizzmekia S., Flach, Britta, Jackson, Lisa, Leav, Brett, Ledgerwood, Julie E., Luke, Catherine J., Makowski, Mat, Nason, Martha C., Roberts, Paul C., Roederer, Mario, Rebolledo, Paulina A., Rostad, Christina A., Rouphael, Nadine G., Shi, Wei, Wang, Lingshu, Widge, Alicia T., Yang, Eun Sung, Beigel, John H., Graham, Barney S., Mascola, John R., Suthar, Mehul S., McDermott, Adrian B., Doria-Rose, Nicole A., Arega, Jae, Beigel, John H., Buchanan, Wendy, Elsafy, Mohammed, Hoang, Binh, Lampley, Rebecca, Kolhekar, Aparna, Koo, Hyung, Luke, Catherine, Makhene, Mamodikoe, Nayak, Seema, Pikaart-Tautges, Rhonda, Roberts, Paul C., Russell, Janie, Sindall, Elisa, Albert, Jim, Kunwar, Pratap, Makowski, Mat, Anderson, Evan J., Bechnak, Amer, Bower, Mary, Camacho-Gonzalez, Andres F., Collins, Matthew, Drobeniuc, Ana, Edara, Venkata Viswanadh, Edupuganti, Srilatha, Floyd, Katharine, Gibson, Theda, Ackerley, Cassie M. Grimsley, Johnson, Brandi, Kamidani, Satoshi, Kao, Carol, Kelley, Colleen, Lai, Lilin, Macenczak, Hollie, McCullough, Michele Paine, Peters, Etza, Phadke, Varun K., Rebolledo, Paulina A., Rostad, Christina A., Rouphael, Nadine, Scherer, Erin, Sherman, Amy, Stephens, Kathy, Suthar, Mehul S., Teherani, Mehgan, Traenkner, Jessica, Winston, Juton, Yildirim, Inci, Barr, Lee, Benoit, Joyce, Carste, Barbara, Choe, Joe, Dunstan, Maya, Erolin, Roxanne, ffitch, Jana, Fields, Colin, Jackson, Lisa A., Kiniry, Erika, Lasicka, Susan, Lee, Stella, Nguyen, Matthew, Pimienta, Stephanie, Suyehira, Janice, Witte, Michael, Bennett, Hamilton, Altaras, Nedim Emil, Carfi, Andrea, Hurley, Marjorie, Leav, Brett, Pajon, Rolando, Sun, Wellington, Zaks, Tal, Coler, Rhea N., Larsen, Sasha E., Neuzil, Kathleen M., Lindesmith, Lisa C., Martinez, David R., Munt, Jennifer, Mallory, Michael, Edwards, Caitlin, Baric, Ralph S., Berkowitz, Nina M., Boritz, Eli A., Carlton, Kevin, Corbett, Kizzmekia S., Costner, Pamela, Creanga, Adrian, Doria-Rose, Nicole A., Douek, Daniel C., Flach, Britta, Gaudinski, Martin, Gordon, Ingelise, Graham, Barney S., Holman, LaSonji, Ledgerwood, Julie E., Leung, Kwanyee, Lin, Bob C., Louder, Mark K., Mascola, John R., McDermott, Adrian B., Morabito, Kaitlyn M., Novik, Laura, O’Connell, Sarah, O’Dell, Sijy, Padilla, Marcelino, Pegu, Amarendra, Schmidt, Stephen D., Shi, Wei, Swanson, Phillip A., Talana, Chloe A., Wang, Lingshu, Widge, Alicia T., Yang, Eun Sung, Zhang, Yi, Chappell, James D., Denison, Mark R., Hughes, Tia, Lu, Xiaotao, Pruijssers, Andrea J., Stevens, Laura J., Posavad, Christine M., Gale, Michael, Menachery, Vineet, Shi, Pei-Yong
Publicado 2021