Antitumour imidazotetrazines: past, present… and future?

por Stevens, Malcolm F. G., Wheelhouse, Richard T.
Publicado 2023

Antitumor Quinol PMX464 Is a Cytocidal Anti-trypanosomal Inhibitor Targeting Trypanothione Metabolism

por König, Janine, Wyllie, Susan, Wells, Geoffrey, Stevens, Malcolm F., Wyatt, Paul G., Fairlamb, Alan H.
Publicado 2011

C8-Substituted Imidazotetrazine Analogs Overcome Temozolomide Resistance by Inducing DNA Adducts and DNA Damage

por Yang, Zhikuan, Wei, Danping, Dai, Xiaoli, Stevens, Malcolm F. G., Bradshaw, Tracey D., Luo, Ying, Zhang, Jihong
Publicado 2019

Identification of novel RHPS4-derivative ligands with improved toxicological profiles and telomere-targeting activities

por Rizzo, Angela, Iachettini, Sara, Zizza, Pasquale, Cingolani, Chiara, Porru, Manuela, Artuso, Simona, Stevens, Malcolm, Hummersone, Marc, Biroccio, Annamaria, Salvati, Erica, Leonetti, Carlo
Publicado 2014

Erratum: Identification of novel RHPS4-derivative ligands with improved toxicological profiles and telomere-targeting activities

por Rizzo, Angela, Iachettini, Sara, Zizza, Pasquale, Cingolani, Chiara, Porru, Manuela, Artuso, Simona, Stevens, Malcolm, Hummersone, Marc, Biroccio, Annamaria, Salvati, Erica, Leonetti, Carlo
Publicado 2015

Stabilization of quadruplex DNA perturbs telomere replication leading to the activation of an ATR-dependent ATM signaling pathway

por Rizzo, Angela, Salvati, Erica, Porru, Manuela, D’Angelo, Carmen, Stevens, Malcolm F., D’Incalci, Maurizio, Leonetti, Carlo, Gilson, Eric, Zupi, Gabriella, Biroccio, Annamaria
Publicado 2009

The antitumour activity of 2‐(4‐amino‐3‐methylphenyl)‐5‐fluorobenzothiazole in human gastric cancer models is mediated by AhR signalling

por Wang, Yuling, Liu, Ying, Tang, Tao, Luo, Ying, Stevens, Malcolm F. G., Cheng, Xi, Yang, Yan, Shi, Dongfang, Zhang, Jihong, Bradshaw, Tracey D.
Publicado 2019

RHPS4 G-Quadruplex Ligand Induces Anti-Proliferative Effects in Brain Tumor Cells

por Lagah, Sunil, Tan, I-Li, Radhakrishnan, Priya, Hirst, Robert A., Ward, Jennifer H., O’Callaghan, Chris, Smith, Stuart J., Stevens, Malcolm F. G., Grundy, Richard G., Rahman, Ruman
Publicado 2014

Quinol derivatives as potential trypanocidal agents

por Capes, Amy, Patterson, Stephen, Wyllie, Susan, Hallyburton, Irene, Collie, Iain T., McCarroll, Andrew J., Stevens, Malcolm F.G., Frearson, Julie A., Wyatt, Paul G., Fairlamb, Alan H., Gilbert, Ian H.
Publicado 2012

In search of effective therapies to overcome resistance to Temozolomide in brain tumours

por Bouzinab, Kaouthar, Summers, Helen, Zhang, Jihong, Stevens, Malcolm F. G., Moody, Christopher J., Turyanska, Lyudmila, Thomas, Neil R., Gershkovich, Pavel, Ashford, Marianne B., Vitterso, Emily, Storer, Lisa C. D., Grundy, Richard, Bradshaw, Tracey D.
Publicado 2019

On and off-target effects of telomere uncapping G-quadruplex selective ligands based on pentacyclic acridinium salts

por Iachettini, Sara, Stevens, Malcolm FG, Frigerio, Mark, Hummersone, Marc G, Hutchinson, Ian, Garner, Thomas P, Searle, Mark S, Wilson, David W, Munde, Manoj, Nanjunda, Rupesh, D’Angelo, Carmen, Zizza, Pasquale, Rizzo, Angela, Cingolani, Chiara, De Cicco, Federica, Porru, Manuela, D’Incalci, Maurizio, Leonetti, Carlo, Biroccio, Annamaria, Salvati, Erica
Publicado 2013