Indomethacin Enhances Type 1 Cannabinoid Receptor Signaling

por Laprairie, Robert B., Mohamed, Kawthar A., Zagzoog, Ayat, Kelly, Melanie E. M., Stevenson, Lesley A., Pertwee, Roger, Denovan-Wright, Eileen M., Thakur, Ganesh A.
Publicado 2019

Pharmacological evaluation of enantiomerically separated positive allosteric modulators of cannabinoid 1 receptor, GAT591 and GAT593

por Brandt, Asher L., Garai, Sumanta, Zagzoog, Ayat, Hurst, Dow P., Stevenson, Lesley A., Pertwee, Roger G., Imler, Gregory H., Reggio, Patricia H., Thakur, Ganesh A., Laprairie, Robert B.
Publicado 2022

Design, synthesis and biological evaluation of novel orthosteric-allosteric ligands of the cannabinoid receptor type 2 (CB(2)R)

por Ferrisi, Rebecca, Gado, Francesca, Polini, Beatrice, Ricardi, Caterina, Mohamed, Kawthar A., Stevenson, Lesley A., Ortore, Gabriella, Rapposelli, Simona, Saccomanni, Giuseppe, Pertwee, Roger G., Laprairie, Robert B., Manera, Clementina, Chiellini, Grazia
Publicado 2022

Synthesis and In Vitro Characterization of Selective Cannabinoid CB2 Receptor Agonists: Biological Evaluation against Neuroblastoma Cancer Cells

por Gado, Francesca, Ferrisi, Rebecca, Di Somma, Sarah, Napolitano, Fabiana, Mohamed, Kawthar A., Stevenson, Lesley A., Rapposelli, Simona, Saccomanni, Giuseppe, Portella, Giuseppe, Pertwee, Roger G., Laprairie, Robert B., Malfitano, Anna Maria, Manera, Clementina
Publicado 2022

Design, Synthesis, and Biological Activity of New CB2 Receptor Ligands: from Orthosteric and Allosteric Modulators to Dualsteric/Bitopic Ligands

por Gado, Francesca, Ferrisi, Rebecca, Polini, Beatrice, Mohamed, Kawthar A., Ricardi, Caterina, Lucarini, Elena, Carpi, Sara, Domenichini, Federica, Stevenson, Lesley A., Rapposelli, Simona, Saccomanni, Giuseppe, Nieri, Paola, Ortore, Gabriella, Pertwee, Roger G., Ghelardini, Carla, Di Cesare Mannelli, Lorenzo, Chiellini, Grazia, Laprairie, Robert B., Manera, Clementina
Publicado 2022

Big conductance calcium‐activated potassium channel openers control spasticity without sedation

por Baker, David, Pryce, Gareth, Visintin, Cristina, Sisay, Sofia, Bondarenko, Alexander I, Vanessa Ho, W S, Jackson, Samuel J, Williams, Thomas E, Al‐Izki, Sarah, Sevastou, Ioanna, Okuyama, Masahiro, Graier, Wolfgang F, Stevenson, Lesley A, Tanner, Carolyn, Ross, Ruth, Pertwee, Roger G, Henstridge, Christopher M, Irving, Andrew J, Schulman, Jesse, Powell, Keith, Baker, Mark D, Giovannoni, Gavin, Selwood, David L
Publicado 2017