CNS glucose metabolism in Amyotrophic Lateral Sclerosis: a therapeutic target?

por Tefera, Tesfaye Wolde, Steyn, Frederik J., Ngo, Shyuan T., Borges, Karin
Publicado 2021

Neuronal Lipid Metabolism: Multiple Pathways Driving Functional Outcomes in Health and Disease

por Tracey, Timothy J., Steyn, Frederik J., Wolvetang, Ernst J., Ngo, Shyuan T.
Publicado 2018

Biomarkers of Metabolism in Amyotrophic Lateral Sclerosis

por Kirk, Siobhan E., Tracey, Timothy J., Steyn, Frederik J., Ngo, Shyuan T.
Publicado 2019

Exploring targets and therapies for amyotrophic lateral sclerosis: current insights into dietary interventions

por Ngo, Shyuan T, Mi, Jia D, Henderson, Robert D, McCombe, Pamela A, Steyn, Frederik J
Publicado 2017

Transgenic Adipose-specific Expression of the Nuclear Receptor RORα Drives a Striking Shift in Fat Distribution and Impairs Glycemic Control

por Tuong, Zewen Kelvin, Fitzsimmons, Rebecca, Wang, Shu-Ching Mary, Oh, Tae Gyu, Lau, Patrick, Steyn, Frederik, Thomas, Gethin, Muscat, George E.O.
Publicado 2016

Skeletal muscle in amyotrophic lateral sclerosis

por Shefner, Jeremy M, Musaro, Antonio, Ngo, Shyuan T, Lunetta, Christian, Steyn, Frederik J, Robitaille, Richard, De Carvalho, Mamede, Rutkove, Seward, Ludolph, Albert C, Dupuis, Luc
Publicado 2023

Use of hip- versus wrist-based actigraphy for assessing functional decline and disease progression in patients with motor neuron disease

por Holdom, Cory J., van Unnik, Jordi W. J., van Eijk, Ruben P. A., van den Berg, Leonard H., Henderson, Robert D., Ngo, Shyuan T., Steyn, Frederik J.
Publicado 2023

Lower hypothalamic volume with lower body mass index is associated with shorter survival in patients with amyotrophic lateral sclerosis

por Chang, Jeryn, Shaw, Thomas B., Holdom, Cory J., McCombe, Pamela A., Henderson, Robert D., Fripp, Jurgen, Barth, Markus, Guo, Christine C., Ngo, Shyuan T., Steyn, Frederik J.
Publicado 2022

Monocytes and neutrophils are associated with clinical features in amyotrophic lateral sclerosis

por McGill, Raquel B, Steyn, Frederik J, Ngo, Shyuan T, Thorpe, Kathryn A, Heggie, Susan, Ruitenberg, Marc J, Henderson, Robert D, McCombe, Pamela A, Woodruff, Trent M
Publicado 2020

The complexity of multidisciplinary respiratory care in amyotrophic lateral sclerosis

por Berlowitz, David J., Mathers, Susan, Hutchinson, Karen, Hogden, Anne, Carey, Kate A., Graco, Marnie, Whelan, Brooke-Mai, Charania, Salma, Steyn, Frederik, Allcroft, Peter, Crook, Ashley, Sheers, Nicole L.
Publicado 2023

An exercise “sweet spot” reverses cognitive deficits of aging by growth-hormone-induced neurogenesis

por Blackmore, Daniel G., Steyn, Frederik J., Carlisle, Alison, O’Keeffe, Imogen, Vien, King-Year, Zhou, Xiaoqing, Leiter, Odette, Jhaveri, Dhanisha, Vukovic, Jana, Waters, Michael J., Bartlett, Perry F.
Publicado 2021

17α‐estradiol acts through hypothalamic pro‐opiomelanocortin expressing neurons to reduce feeding behavior

por Steyn, Frederik J., Ngo, Shyuan T., Chen, Vicky Ping, Bailey‐Downs, Lora C., Xie, Teresa Y., Ghadami, Martin, Brimijoin, Stephen, Freeman, Willard M., Rubinstein, Marcelo, Low, Malcolm J., Stout, Michael B.
Publicado 2017

TSH Pulses Finely Tune Thyroid Hormone Release and TSH Receptor Transduction

por Guillou, Anne, Kemkem, Yasmine, Lafont, Chrystel, Fontanaud, Pierre, Calebiro, Davide, Campos, Pauline, Bonnefont, Xavier, Fiordelisio-Coll, Tatiana, Wang, Ying, Brûlé, Emilie, Bernard, Daniel J, Le Tissier, Paul, Steyn, Frederik, Mollard, Patrice
Publicado 2023

Patient with ALS with a novel TBK1 mutation, widespread brain involvement, behaviour changes and metabolic dysfunction

por McCombe, Pamela A, Ngo, Shyuan T, Guo, Christine Cong, Fazlollahi, Amir, Bollmann, Saskia, Wang, Liting, Hu, Xintao, Barth, Markus, Salvado, Olivier, Davis, Mark, Ceslis, Amelia, Robinson, Gail, Henderson, Robert D, Steyn, Frederik J
Publicado 2019

Hypermetabolism in ALS is associated with greater functional decline and shorter survival

por Steyn, Frederik J, Ioannides, Zara A, van Eijk, Ruben P A, Heggie, Susan, Thorpe, Kathryn A, Ceslis, Amelia, Heshmat, Saman, Henders, Anjali K, Wray, Naomi R, van den Berg, Leonard H, Henderson, Robert D, McCombe, Pamela A, Ngo, Shyuan T
Publicado 2018

Addition of a carboxy-terminal tail to the normally tailless gonadotropin-releasing hormone receptor impairs fertility in female mice

por Toufaily, Chirine, Fortin, Jérôme, Alonso, Carlos AI, Lapointe, Evelyne, Zhou, Xiang, Santiago-Andres, Yorgui, Lin, Yeu-Farn, Cui, Yiming, Wang, Ying, Devost, Dominic, Roelfsema, Ferdinand, Steyn, Frederik, Hanyaloglu, Aylin C, Hébert, Terence E, Fiordelisio, Tatiana, Boerboom, Derek, Bernard, Daniel J
Publicado 2021

Skeletal-Muscle Metabolic Reprogramming in ALS-SOD1(G93A) Mice Predates Disease Onset and Is A Promising Therapeutic Target

por Scaricamazza, Silvia, Salvatori, Illari, Giacovazzo, Giacomo, Loeffler, Jean Philippe, Renè, Frederique, Rosina, Marco, Quessada, Cyril, Proietti, Daisy, Heil, Constantin, Rossi, Simona, Battistini, Stefania, Giannini, Fabio, Volpi, Nila, Steyn, Frederik J., Ngo, Shyuan T., Ferraro, Elisabetta, Madaro, Luca, Coccurello, Roberto, Valle, Cristiana, Ferri, Alberto
Publicado 2020

Patient perspectives on digital healthcare technology in care and clinical trials for motor neuron disease: an international survey

por Helleman, Jochem, Johnson, Barbara, Holdom, Cory, Hobson, Esther, Murray, Deirdre, Steyn, Frederik J., Ngo, Shyuan T., Henders, Anjali, Lokeshappa, Madhura B., Visser-Meily, Johanna M. A., van den Berg, Leonard H., Hardiman, Orla, Beelen, Anita, McDermott, Chris, van Eijk, Ruben P. A.
Publicado 2022

A Road Map for Remote Digital Health Technology for Motor Neuron Disease

por van Eijk, Ruben P A, Beelen, Anita, Kruitwagen, Esther T, Murray, Deirdre, Radakovic, Ratko, Hobson, Esther, Knox, Liam, Helleman, Jochem, Burke, Tom, Rubio Pérez, Miguel Ángel, Reviers, Evy, Genge, Angela, Steyn, Frederik J, Ngo, Shyuan, Eaglesham, John, Roes, Kit C B, van den Berg, Leonard H, Hardiman, Orla, McDermott, Christopher J
Publicado 2021

Altered skeletal muscle glucose–fatty acid flux in amyotrophic lateral sclerosis

por Steyn, Frederik J, Li, Rui, Kirk, Siobhan E, Tefera, Tesfaye W, Xie, Teresa Y, Tracey, Timothy J, Kelk, Dean, Wimberger, Elyse, Garton, Fleur C, Roberts, Llion, Chapman, Sarah E, Coombes, Jeff S, Leevy, W Matthew, Ferri, Alberto, Valle, Cristiana, René, Frédérique, Loeffler, Jean-Philippe, McCombe, Pamela A, Henderson, Robert D, Ngo, Shyuan T
Publicado 2020