Theoretical analysis reveals a role for RAF conformational autoinhibition in paradoxical activation

por Mendiratta, Gaurav, Stites, Edward
Publicado 2023

Quantitative Systems Pharmacology Analysis of KRAS G12C Covalent Inhibitors

por Stites, Edward C., Shaw, Andrey S.
Publicado 2018

A mechanism for the response of KRAS(G13D) expressing colorectal cancers to EGFR inhibitors

por McFall, Thomas, Stites, Edward Cooper
Publicado 2020

The Interpretation of SARS-CoV-2 Diagnostic Tests

por Stites, Edward C., Wilen, Craig B.
Publicado 2020

Identification of RAS mutant biomarkers for EGFR inhibitor sensitivity using a systems biochemical approach

por McFall, Thomas, Stites, Edward C.
Publicado 2021

How often is each gene mutated within the cancer patient population?

por Mendiratta, Gaurav, Jones, Michael K., Stites, Edward C.
Publicado 2022

Discernment between candidate mechanisms for KRAS G13D colorectal cancer sensitivity to EGFR inhibitors

por McFall, Thomas, Schomburg, Noah K., Rossman, Kent L., Stites, Edward C.
Publicado 2020

Cancer gene mutation frequencies for the U.S. population

por Mendiratta, Gaurav, Ke, Eugene, Aziz, Meraj, Liarakos, David, Tong, Melinda, Stites, Edward C.
Publicado 2021

Co-targeting KRAS G12C and EGFR reduces both mutant and wild-type RAS-GTP

por McFall, Thomas, Trogdon, Michael, Guizar, Anita C., Langenheim, John F., Sisk-Hackworth, Laura, Stites, Edward C.
Publicado 2022

KRAS‐Mutated, Estrogen Receptor‐Positive Low‐Grade Serous Ovarian Cancer: Unraveling an Exceptional Response Mystery

por Kato, Shumei, McFall, Thomas, Takahashi, Kenta, Bamel, Kasey, Ikeda, Sadakatsu, Eskander, Ramez N., Plaxe, Steven, Parker, Barbara, Stites, Edward, Kurzrock, Razelle
Publicado 2021

Specification, annotation, visualization and simulation of a large rule-based model for ERBB receptor signaling

por Creamer, Matthew S, Stites, Edward C, Aziz, Meraj, Cahill, James A, Tan, Chin Wee, Berens, Michael E, Han, Haiyong, Bussey, Kimberley J, Von Hoff, Daniel D, Hlavacek, William S, Posner, Richard G
Publicado 2012

Modeling cell line-specific recruitment of signaling proteins to the insulin-like growth factor 1 receptor

por Erickson, Keesha E., Rukhlenko, Oleksii S., Shahinuzzaman, Md, Slavkova, Kalina P., Lin, Yen Ting, Suderman, Ryan, Stites, Edward C., Anghel, Marian, Posner, Richard G., Barua, Dipak, Kholodenko, Boris N., Hlavacek, William S.
Publicado 2019

Real-world data from a molecular tumor board demonstrates improved outcomes with a precision N-of-One strategy

por Kato, Shumei, Kim, Ki Hwan, Lim, Hyo Jeong, Boichard, Amelie, Nikanjam, Mina, Weihe, Elizabeth, Kuo, Dennis J., Eskander, Ramez N., Goodman, Aaron, Galanina, Natalie, Fanta, Paul T., Schwab, Richard B., Shatsky, Rebecca, Plaxe, Steven C., Sharabi, Andrew, Stites, Edward, Adashek, Jacob J., Okamura, Ryosuke, Lee, Suzanna, Lippman, Scott M., Sicklick, Jason K., Kurzrock, Razelle
Publicado 2020

Genome-Wide Characterization of Pancreatic Adenocarcinoma Patients Using Next Generation Sequencing

por Liang, Winnie S., Craig, David W., Carpten, John, Borad, Mitesh J., Demeure, Michael J., Weiss, Glen J., Izatt, Tyler, Sinari, Shripad, Christoforides, Alexis, Aldrich, Jessica, Kurdoglu, Ahmet, Barrett, Michael, Phillips, Lori, Benson, Hollie, Tembe, Waibhav, Braggio, Esteban, Kiefer, Jeffrey A., Legendre, Christophe, Posner, Richard, Hostetter, Galen H., Baker, Angela, Egan, Jan B., Han, Haiyong, Lake, Douglas, Stites, Edward C., Ramanathan, Ramesh K., Fonseca, Rafael, Stewart, A. Keith, Von Hoff, Daniel
Publicado 2012