Timing Facilitated Site Transfer of an Enzyme on DNA

por Schonhoft, Joseph D., Stivers, James T.
Publicado 2012

Variola Type IB DNA Topoisomerase: DNA Binding and Supercoil Unwinding Using Engineered DNA Minicircles

por Anderson, Breeana G., Stivers, James T.
Publicado 2014

Deoxyuridine in DNA has an inhibitory and promutagenic effect on RNA transcription by diverse RNA polymerases

por Cui, Junru, Gizzi, Anthony, Stivers, James T
Publicado 2019

Nontarget DNA binding shapes the dynamic landscape for enzymatic recognition of DNA damage

por Friedman, Joshua I., Majumdar, Ananya, Stivers, James T.
Publicado 2009

Electrostatic Properties of Complexes along a DNA Glycosylase Damage Search Pathway

por Cravens, Shannen L., Hobson, Matthew, Stivers, James T.
Publicado 2014

Linking uracil base excision repair and 5-fluorouracil toxicity in yeast

por Seiple, Lauren, Jaruga, Pawel, Dizdaroglu, Miral, Stivers, James T.
Publicado 2006

N-terminal domain of human uracil DNA glycosylase (hUNG2) promotes targeting to uracil sites adjacent to ssDNA–dsDNA junctions

por Weiser, Brian P, Rodriguez, Gaddiel, Cole, Philip A, Stivers, James T
Publicado 2018

Impact of linker strain and flexibility in the design of a fragment-based inhibitor

por Chung, Suhman, Parker, Jared B., Bianchet, Mario, Amzel, L. Mario, Stivers, James T.
Publicado 2009

SAMHD1 is a single-stranded nucleic acid binding protein with no active site-associated nuclease activity

por Seamon, Kyle J., Sun, Zhiqiang, Shlyakhtenko, Luda S., Lyubchenko, Yuri L., Stivers, James T.
Publicado 2015

Measurement of nanoscale DNA translocation by uracil DNA glycosylase in human cells

por Esadze, Alexandre, Rodriguez, Gaddiel, Weiser, Brian P., Cole, Philip A., Stivers, James T.
Publicado 2017

Deficient uracil base excision repair leads to persistent dUMP in HIV proviruses during infection of monocytes and macrophages

por Meshesha, Mesfin, Esadze, Alexandre, Cui, Junru, Churgulia, Natela, Sahu, Sushil Kumar, Stivers, James T.
Publicado 2020

Microscopic mechanism of DNA damage searching by hOGG1

por Rowland, Meng M., Schonhoft, Joseph D., McKibbin, Paige L., David, Sheila S., Stivers, James T.
Publicado 2014

Mimicking damaged DNA with a small molecule inhibitor of human UNG2

por Krosky, Daniel J., Bianchet, Mario A., Seiple, Lauren, Chung, Suhman, Amzel, L. Mario, Stivers, James T.
Publicado 2006

Replication-competent HIV-1 in human alveolar macrophages and monocytes despite nucleotide pools with elevated dUTP

por Cui, Junru, Meshesha, Mesfin, Churgulia, Natela, Merlo, Christian, Fuchs, Edward, Breakey, Jennifer, Jones, Joyce, Stivers, James T.
Publicado 2022

Molecular crowding enhances facilitated diffusion of two human DNA glycosylases

por Cravens, Shannen L., Schonhoft, Joseph D., Rowland, Meng M., Rodriguez, Alyssa A., Anderson, Breeana G., Stivers, James T.
Publicado 2015

AID/APOBEC deaminases disfavor modified cytosines implicated in DNA demethylation

por Nabel, Christopher S., Jia, Huijue, Ye, Yu, Shen, Li, Goldschmidt, Hana L., Stivers, James T., Zhang, Yi, Kohli, Rahul M.
Publicado 2012

High-throughput mutagenesis reveals functional determinants for DNA targeting by activation-induced deaminase

por Gajula, Kiran S., Huwe, Peter J., Mo, Charlie Y., Crawford, Daniel J., Stivers, James T., Radhakrishnan, Ravi, Kohli, Rahul M.
Publicado 2014

Small Molecule Inhibition of SAMHD1 dNTPase by Tetramer Destabilization

por Seamon, Kyle J., Hansen, Erik C., Kadina, Anastasia P., Kashemirov, Boris A., McKenna, Charles E., Bumpus, Namandjé N., Stivers, James T.
Publicado 2014

Phosphorylation of SAMHD1 Thr592 increases C-terminal domain dynamics, tetramer dissociation and ssDNA binding kinetics

por Orris, Benjamin, Huynh, Kevin W, Ammirati, Mark, Han, Seungil, Bolaños, Ben, Carmody, Jason, Petroski, Matthew D, Bosbach, Benedikt, Shields, David J, Stivers, James T
Publicado 2022

Guanine-containing ssDNA and RNA induce dimeric and tetrameric SAMHD1 in cryo-EM and binding studies

por Orris, Benjamin, Sung, Min Woo, Bhat, Shridhar, Xu, Yingrong, Huynh, Kevin W., Han, Seungil, Johnson, Darren C., Bosbach, Benedikt, Shields, David J., Stivers, James T.
Publicado 2023