Huntington’s Disease iPSC-Derived Brain Microvascular Endothelial Cells Reveal WNT-Mediated Angiogenic and Blood-Brain Barrier Deficits

por Lim, Ryan G., Quan, Chris, Reyes-Ortiz, Andrea M., Lutz, Sarah E., Kedaigle, Amanda J., Gipson, Theresa A., Wu, Jie, Vatine, Gad D., Stocksdale, Jennifer, Casale, Malcolm S., Svendsen, Clive N., Fraenkel, Ernest, Housman, David E., Agalliu, Dritan, Thompson, Leslie M.
Publicado 2017

Aberrant Development Corrected in Adult-Onset Huntington's Disease iPSC-Derived Neuronal Cultures via WNT Signaling Modulation

por Smith-Geater, Charlene, Hernandez, Sarah J., Lim, Ryan G., Adam, Miriam, Wu, Jie, Stocksdale, Jennifer T., Wassie, Brook T., Gold, Maxwell Philip, Wang, Keona Q., Miramontes, Ricardo, Kopan, Lexi, Orellana, Iliana, Joy, Shona, Kemp, Paul J., Allen, Nicholas D., Fraenkel, Ernest, Thompson, Leslie M.
Publicado 2020

Microglia do not restrict SARS-CoV-2 replication following infection of the central nervous system of K18-hACE2 transgenic mice

por Olivarria, Gema M., Cheng, Yuting, Furman, Susana, Pachow, Collin, Hohsfield, Lindsay A., Smith-Geater, Charlene, Miramontes, Ricardo, Wu, Jie, Burns, Mara S., Tsourmas, Kate I., Stocksdale, Jennifer, Manlapaz, Cynthia, Yong, William H., Teijaro, John, Edwards, Robert, Green, Kim N., Thompson, Leslie M., Lane, Thomas E.
Publicado 2021

Microglia Do Not Restrict SARS-CoV-2 Replication following Infection of the Central Nervous System of K18-Human ACE2 Transgenic Mice

por Olivarria, Gema M., Cheng, Yuting, Furman, Susana, Pachow, Collin, Hohsfield, Lindsay A., Smith-Geater, Charlene, Miramontes, Ricardo, Wu, Jie, Burns, Mara S., Tsourmas, Kate I., Stocksdale, Jennifer, Manlapaz, Cynthia, Yong, William H., Teijaro, John, Edwards, Robert, Green, Kim N., Thompson, Leslie M., Lane, Thomas E.
Publicado 2022

A Comparison of mRNA Sequencing with Random Primed and 3′-Directed Libraries

por Xiong, Yuguang, Soumillon, Magali, Wu, Jie, Hansen, Jens, Hu, Bin, van Hasselt, Johan G. C., Jayaraman, Gomathi, Lim, Ryan, Bouhaddou, Mehdi, Ornelas, Loren, Bochicchio, Jim, Lenaeus, Lindsay, Stocksdale, Jennifer, Shim, Jaehee, Gomez, Emilda, Sareen, Dhruv, Svendsen, Clive, Thompson, Leslie M., Mahajan, Milind, Iyengar, Ravi, Sobie, Eric A., Azeloglu, Evren U., Birtwistle, Marc R.
Publicado 2017

PIAS1 modulates striatal transcription, DNA damage repair, and SUMOylation with relevance to Huntington’s disease

por Morozko, Eva L., Smith-Geater, Charlene, Monteys, Alejandro Mas, Pradhan, Subrata, Lim, Ryan G., Langfelder, Peter, Kachemov, Marketta, Hill, Austin, Stocksdale, Jennifer T., Cullis, Pieter R., Wu, Jie, Ochaba, Joseph, Miramontes, Ricardo, Chakraborty, Anirban, Hazra, Tapas K., Lau, Alice, St-cyr, Sophie, Orellana, Iliana, Kopan, Lexi, Wang, Keona Q., Yeung, Sylvia, Leavitt, Blair R., Reidling, Jack C., Yang, X. William, Steffan, Joan S., Davidson, Beverly L., Sarkar, Partha S., Thompson, Leslie M.
Publicado 2021

An integrated multi-omic analysis of iPSC-derived motor neurons from C9ORF72 ALS patients

por Li, Jonathan, Lim, Ryan G., Kaye, Julia A., Dardov, Victoria, Coyne, Alyssa N., Wu, Jie, Milani, Pamela, Cheng, Andrew, Thompson, Terri G., Ornelas, Loren, Frank, Aaron, Adam, Miriam, Banuelos, Maria G., Casale, Malcolm, Cox, Veerle, Escalante-Chong, Renan, Daigle, J. Gavin, Gomez, Emilda, Hayes, Lindsey, Holewenski, Ronald, Lei, Susan, Lenail, Alex, Lima, Leandro, Mandefro, Berhan, Matlock, Andrea, Panther, Lindsay, Patel-Murray, Natasha Leanna, Pham, Jacqueline, Ramamoorthy, Divya, Sachs, Karen, Shelley, Brandon, Stocksdale, Jennifer, Trost, Hannah, Wilhelm, Mark, Venkatraman, Vidya, Wassie, Brook T., Wyman, Stacia, Yang, Stephanie, Van Eyk, Jennifer E., Lloyd, Thomas E., Finkbeiner, Steven, Fraenkel, Ernest, Rothstein, Jeffrey D., Sareen, Dhruv, Svendsen, Clive N., Thompson, Leslie M.
Publicado 2021

Answer ALS, a large-scale resource for sporadic and familial ALS combining clinical and multi-omics data from induced pluripotent cell lines

por Baxi, Emily G., Thompson, Terri, Li, Jonathan, Kaye, Julia A., Lim, Ryan G., Wu, Jie, Ramamoorthy, Divya, Lima, Leandro, Vaibhav, Vineet, Matlock, Andrea, Frank, Aaron, Coyne, Alyssa N., Landin, Barry, Ornelas, Loren, Mosmiller, Elizabeth, Thrower, Sara, Farr, S. Michelle, Panther, Lindsey, Gomez, Emilda, Galvez, Erick, Perez, Daniel, Meepe, Imara, Lei, Susan, Mandefro, Berhan, Trost, Hannah, Pinedo, Louis, Banuelos, Maria G., Liu, Chunyan, Moran, Ruby, Garcia, Veronica, Workman, Michael, Ho, Richie, Wyman, Stacia, Roggenbuck, Jennifer, Harms, Matthew B., Stocksdale, Jennifer, Miramontes, Ricardo, Wang, Keona, Venkatraman, Vidya, Holewenski, Ronald, Sundararaman, Niveda, Pandey, Rakhi, Manalo, Danica-Mae, Donde, Aneesh, Huynh, Nhan, Adam, Miriam, Wassie, Brook T., Vertudes, Edward, Amirani, Naufa, Raja, Krishna, Thomas, Reuben, Hayes, Lindsey, Lenail, Alex, Cerezo, Aianna, Luppino, Sarah, Farrar, Alanna, Pothier, Lindsay, Prina, Carolyn, Morgan, Todd, Jamil, Arish, Heintzman, Sarah, Jockel-Balsarotti, Jennifer, Karanja, Elizabeth, Markway, Jesse, McCallum, Molly, Joslin, Ben, Alibazoglu, Deniz, Kolb, Stephen, Ajroud-Driss, Senda, Baloh, Robert, Heitzman, Daragh, Miller, Tim, Glass, Jonathan D., Patel-Murray, Natasha Leanna, Yu, Hong, Sinani, Ervin, Vigneswaran, Prasha, Sherman, Alexander V., Ahmad, Omar, Roy, Promit, Beavers, Jay C., Zeiler, Steven, Krakauer, John W., Agurto, Carla, Cecchi, Guillermo, Bellard, Mary, Raghav, Yogindra, Sachs, Karen, Ehrenberger, Tobias, Bruce, Elizabeth, Cudkowicz, Merit E., Maragakis, Nicholas, Norel, Raquel, Van Eyk, Jennifer E., Finkbeiner, Steven, Berry, James, Sareen, Dhruv, Thompson, Leslie M., Fraenkel, Ernest, Svendsen, Clive N., Rothstein, Jeffrey D.
Publicado 2022