A Hybrid Model for Safety Pharmacology on an Automated Patch Clamp Platform: Using Dynamic Clamp to Join iPSC-Derived Cardiomyocytes and Simulations of I(k1) Ion Channels in Real-T...

por Goversen, Birgit, Becker, Nadine, Stoelzle-Feix, Sonja, Obergrussberger, Alison, Vos, Marc A., van Veen, Toon A. B., Fertig, Niels, de Boer, Teun P.
Publicado 2018

Cross-site and cross-platform variability of automated patch clamp assessments of drug effects on human cardiac currents in recombinant cells

por Kramer, James, Himmel, Herbert M., Lindqvist, Anders, Stoelzle-Feix, Sonja, Chaudhary, Khuram W., Li, Dingzhou, Bohme, Georg Andrees, Bridgland-Taylor, Matthew, Hebeisen, Simon, Fan, Jingsong, Renganathan, Muthukrishnan, Imredy, John, Humphries, Edward S. A., Brinkwirth, Nina, Strassmaier, Tim, Ohtsuki, Atsushi, Danker, Timm, Vanoye, Carlos, Polonchuk, Liudmila, Fermini, Bernard, Pierson, Jennifer Beck, Gintant, Gary
Publicado 2020

Publisher Correction: Cross-site and cross-platform variability of automated patch clamp assessments of drug effects on human cardiac currents in recombinant cells

por Kramer, James, Himmel, Herbert M., Lindqvist, Anders, Stoelzle-Feix, Sonja, Chaudhary, Khuram W., Li, Dingzhou, Bohme, Georg Andrees, Bridgland-Taylor, Matthew, Hebeisen, Simon, Fan, Jingsong, Renganathan, Muthukrishnan, Imredy, John, Humphries, Edward S. A., Brinkwirth, Nina, Strassmaier, Tim, Ohtsuki, Atsushi, Danker, Timm, Vanoye, Carlos, Polonchuk, Liudmila, Fermini, Bernard, Pierson, Jennifer Beck, Gintant, Gary
Publicado 2020

A systematic strategy for estimating hERG block potency and its implications in a new cardiac safety paradigm

por Ridder, Bradley J., Leishman, Derek J., Bridgland-Taylor, Matthew, Samieegohar, Mohammadreza, Han, Xiaomei, Wu, Wendy W., Randolph, Aaron, Tran, Phu, Sheng, Jiansong, Danker, Timm, Lindqvist, Anders, Konrad, Daniel, Hebeisen, Simon, Polonchuk, Liudmila, Gissinger, Evgenia, Renganathan, Muthukrishnan, Koci, Bryan, Wei, Haiyang, Fan, Jingsong, Levesque, Paul, Kwagh, Jae, Imredy, John, Zhai, Jin, Rogers, Marc, Humphries, Edward, Kirby, Robert, Stoelzle-Feix, Sonja, Brinkwirth, Nina, Rotordam, Maria Giustina, Becker, Nadine, Friis, Søren, Rapedius, Markus, Goetze, Tom A., Strassmaier, Tim, Okeyo, George, Kramer, James, Kuryshev, Yuri, Wu, Caiyun, Himmel, Herbert, Mirams, Gary R., Strauss, David G., Bardenet, Rémi, Li, Zhihua
Publicado 2020

Corrigendum to “A systematic strategy for estimating hERG block potency and its implications in a new cardiac safety paradigm” [Toxicology and Applied Pharmacology volume 394C (202...

por Ridder, Bradley J., Leishman, Derek J., Bridgland-Taylor, Matthew, Samieegohar, Mohammadreza, Han, Xiaomei, Wu, Wendy W., Randolph, Aaron, Tran, Phu, Sheng, Jiansong, Danker, Timm, Lindqvist, Anders, Konrad, Daniel, Hebeisen, Simon, Polonchuk, Liudmila, Gissinger, Evgenia, Renganathan, Muthukrishnan, Koci, Bryan, Wei, Haiyang, Fan, Jingsong, Levesque, Paul, Kwagh, Jae, Imredy, John, Zhai, Jin, Rogers, Marc, Humphries, Edward, Kirby, Robert, Stoelzle-Feix, Sonja, Brinkwirth, Nina, Rotordam, Maria Giustina, Becker, Nadine, Friis, Søren, Rapedius, Markus, Goetze, Tom A., Strassmaier, Tim, Okeyo, George, Kramer, James, Kuryshev, Yuri, Wu, Caiyun, Himmel, Herbert, Mirams, Gary R., Strauss, David G., Bardenet, Remi, Li, Zhihua
Publicado 2020