Identification of Functional and Druggable Sites in Aspergillus fumigatus Essential Phosphatases by Virtual Screening

por Thornton, Benjamin P., Johns, Anna, Al-Shidhani, Reem, Álvarez-Carretero, Sandra, Storer, Isabelle S. R., Bromley, Michael J., Tabernero, Lydia
Publicado 2019

Antagonism of the Azoles to Olorofim and Cross-Resistance Are Governed by Linked Transcriptional Networks in Aspergillus fumigatus

por van Rhijn, Norman, Hemmings, Sam, Storer, Isabelle S. R., Valero, Clara, Bin Shuraym, Hajer, Goldman, Gustavo H., Gsaller, Fabio, Amich, Jorge, Bromley, Michael J.
Publicado 2022

Functional analysis of the Aspergillus fumigatus kinome reveals a DYRK kinase involved in septal plugging is a novel antifungal drug target

por van Rhijn, Norman, Zhao, Can, Al-Furaji, Narjes, Storer, Isabelle, Valero, Clara, Gago, Sara, Chown, Harry, Baldin, Clara, Fortune-Grant, Rachael, Shuraym, Hajer Bin, Ivanova, Lia, Kniemeyer, Olaf, Krüger, Thomas, Bignell, Elaine, Goldman, Gustavo, Amich, Jorge, Delneri, Daniela, Bowyer, Paul, Brakhage, Axel, Haas, Hubertus, Bromley, Michael
Publicado 2023