Human CD19-specific switchable CAR T-cells are efficacious as constitutively active CAR T-cells but cause less morbidity in a mouse model of human CD19(+) malignancy

por Pennell, Christopher A, Campbell, Heather, Storlie, Meghan D, Bolivar-Wagers, Sara, Osborn, Mark J, Refaeli, Yosef, Jensen, Michael, Viaud, Sophie, Young, Travis S, Blazar, Bruce R
Publicado 2022

Novel CRISPR-Associated Gene-Editing Systems Discovered in Metagenomic Samples Enable Efficient and Specific Genome Engineering

por Lamothe, Rebecca C., Storlie, Meghan D., Espinosa, Diego A., Rudlaff, Rachel, Browne, Patrick, Liu, Jason, Rivas, Andres, Devoto, Audra, Oki, Jennifer, Khoubyari, Ashcon, Goltsman, Daniela S. Aliaga, Lin, Jyun-Liang, Butterfield, Cristina N., Brown, Christopher T., Thomas, Brian C., Cost, Gregory J.
Publicado 2023