Anion-Sensitive Fluorophore Identifies the Drosophila Swell-Activated Chloride Channel in a Genome-Wide RNA Interference Screen

por Stotz, Stephanie C., Clapham, David E.
Publicado 2012

Citral Sensing by TRANSient Receptor Potential Channels in Dorsal Root Ganglion Neurons

por Stotz, Stephanie C., Vriens, Joris, Martyn, Derek, Clardy, Jon, Clapham, David E.
Publicado 2008

Correction: Citral Sensing by Transient Receptor Potential Channels in Dorsal Root Ganglion Neurons

por Stotz, Stephanie C., Vriens, Joris, Martyn, Derek, Clardy, Jon, Clapham, David E.
Publicado 2008

Apabetalone, a Clinical-Stage, Selective BET Inhibitor, Opposes DUX4 Target Gene Expression in Primary Human FSHD Muscle Cells

por Sarsons, Christopher D., Gilham, Dean, Tsujikawa, Laura M., Wasiak, Sylwia, Fu, Li, Rakai, Brooke D., Stotz, Stephanie C., Carestia, Agostina, Sweeney, Michael, Kulikowski, Ewelina
Publicado 2023

Inorganic polyphosphate regulates neuronal excitability through modulation of voltage-gated channels

por Stotz, Stephanie C, Scott, Lucas OM, Drummond-Main, Christopher, Avchalumov, Yosef, Girotto, Fernando, Davidsen, Jörn, Gómez-Gárcia, Maria R, Rho, Jong M, Pavlov, Evgeny V, Colicos, Michael A
Publicado 2014

Benefit of Apabetalone on Plasma Proteins in Renal Disease

por Wasiak, Sylwia, Tsujikawa, Laura M., Halliday, Christopher, Stotz, Stephanie C., Gilham, Dean, Jahagirdar, Ravi, Kalantar-Zadeh, Kamyar, Robson, Richard, Sweeney, Michael, Johansson, Jan O., Wong, Norman C., Kulikowski, Ewelina
Publicado 2017

Inhibition of epigenetic reader proteins by apabetalone counters inflammation in activated innate immune cells from Fabry disease patients receiving enzyme replacement therapy

por Fu, Li, Wasiak, Sylwia, Tsujikawa, Laura M., Rakai, Brooke D., Stotz, Stephanie C., Wong, Norman C. W., Johansson, Jan O., Sweeney, Michael, Mohan, Connie M., Khan, Aneal, Kulikowski, Ewelina
Publicado 2022

Dual mechanism: Epigenetic inhibitor apabetalone reduces SARS-CoV-2 Delta and Omicron variant spike binding and attenuates SARS-CoV-2 RNA induced inflammation

por Fu, Li, Gilham, Dean, Stotz, Stephanie C., Sarsons, Christopher D., Rakai, Brooke D., Tsujikawa, Laura M., Wasiak, Sylwia, Johansson, Jan O., Sweeney, Michael, Wong, Norman C.W., Kulikowski, Ewelina
Publicado 2023

Epigenetic Modulation by Apabetalone Counters Cytokine-Driven Acute Phase Response In Vitro, in Mice and in Patients with Cardiovascular Disease

por Wasiak, Sylwia, Gilham, Dean, Daze, Emily, Tsujikawa, Laura M., Halliday, Christopher, Stotz, Stephanie C., Rakai, Brooke D., Fu, Li, Jahagirdar, Ravi, Sweeney, Michael, Johansson, Jan O., Wong, Norman C. W., Kulikowski, Ewelina
Publicado 2020

Bromodomain and Extraterminal Protein Inhibitor, Apabetalone (RVX-208), Reduces ACE2 Expression and Attenuates SARS-Cov-2 Infection In Vitro

por Gilham, Dean, Smith, Audrey L., Fu, Li, Moore, Dalia Y., Muralidharan, Abenaya, Reid, St. Patrick M., Stotz, Stephanie C., Johansson, Jan O., Sweeney, Michael, Wong, Norman C. W., Kulikowski, Ewelina, El-Gamal, Dalia
Publicado 2021

BET protein inhibitor apabetalone (RVX-208) suppresses pro-inflammatory hyper-activation of monocytes from patients with cardiovascular disease and type 2 diabetes

por Wasiak, Sylwia, Dzobo, Kim E., Rakai, Brooke D., Kaiser, Yannick, Versloot, Miranda, Bahjat, Mahnoush, Stotz, Stephanie C., Fu, Li, Sweeney, Michael, Johansson, Jan O., Wong, Norman C. W., Stroes, Erik S. G., Kroon, Jeffrey, Kulikowski, Ewelina
Publicado 2020

Apabetalone (RVX-208) reduces vascular inflammation in vitro and in CVD patients by a BET-dependent epigenetic mechanism

por Tsujikawa, Laura M., Fu, Li, Das, Shovon, Halliday, Christopher, Rakai, Brooke D., Stotz, Stephanie C., Sarsons, Christopher D., Gilham, Dean, Daze, Emily, Wasiak, Sylwia, Studer, Deborah, Rinker, Kristina D., Sweeney, Michael, Johansson, Jan O., Wong, Norman C. W., Kulikowski, Ewelina
Publicado 2019