Assessment of disulfide and hinge modifications in monoclonal antibodies

por Moritz, Bernd, Stracke, Jan Olaf
Publicado 2017

Oxidation in the complementarity-determining regions differentially influences the properties of therapeutic antibodies

por Dashivets, Tetyana, Stracke, Jan, Dengl, Stefan, Knaupp, Alexander, Pollmann, Jan, Buchner, Johannes, Schlothauer, Tilman
Publicado 2016

Matrix metalloproteinases in arthritic disease

por Murphy, Gillian, Knäuper, Vera, Atkinson, Susan, Butler, George, English, William, Hutton, Mike, Stracke, Jan, Clark, Ian
Publicado 2002

Application of affinity capillary electrophoresis for charge heterogeneity profiling of biopharmaceuticals

por Hutanu, Andrei, Kiessig, Steffen, Bathke, Andrea, Ketterer, Rolf, Riner, Sonja, Olaf Stracke, Jan, Wild, Markus, Moritz, Bernd
Publicado 2019

Optimization of capillary zone electrophoresis for charge heterogeneity testing of biopharmaceuticals using enhanced method development principles

por Moritz, Bernd, Locatelli, Valentina, Niess, Michele, Bathke, Andrea, Kiessig, Steffen, Entler, Barbara, Finkler, Christof, Wegele, Harald, Stracke, Jan
Publicado 2017

Methionine oxidation of proteins analyzed by affinity capillary electrophoresis in presence of silver(I) and gold(III) ions

por Hutanu, Andrei, Hauser, Peter C., Moritz, Bernd, Kiessig, Steffen, Noël, Aurélie, Stracke, Jan O., Wild, Markus, Schwarz, Maria A.
Publicado 2021

Simultaneous Assessment of Asp Isomerization and Asn Deamidation in Recombinant Antibodies by LC-MS following Incubation at Elevated Temperatures

por Diepold, Katharina, Bomans, Katrin, Wiedmann, Michael, Zimmermann, Boris, Petzold, Andreas, Schlothauer, Tilman, Mueller, Robert, Moritz, Bernd, Stracke, Jan Olaf, Mølhøj, Michael, Reusch, Dietmar, Bulau, Patrick
Publicado 2012

A novel approach to investigate the effect of methionine oxidation on pharmacokinetic properties of therapeutic antibodies

por Stracke, Jan, Emrich, Thomas, Rueger, Petra, Schlothauer, Tilman, Kling, Lothar, Knaupp, Alexander, Hertenberger, Hubert, Wolfert, Andreas, Spick, Christian, Lau, Wilma, Drabner, Georg, Reiff, Ulrike, Koll, Hans, Papadimitriou, Apollon
Publicado 2014

Identification of Hetero-aggregates in Antibody Co-formulations by Multi-dimensional Liquid Chromatography Coupled to Mass Spectrometry

por Kuhne, Felix, Heinrich, Katrin, Winter, Martin, Fichtl, Jürgen, Hoffmann, Gabriel, Zähringer, Franziska, Spitzauer, Katharina, Meier, Monika, Khan, Tarik A., Bonnington, Lea, Wagner, Katharina, Stracke, Jan Olaf, Reusch, Dietmar, Wegele, Harald, Mormann, Michael, Bulau, Patrick
Publicado 2023

Targeted siRNA Delivery and mRNA Knockdown Mediated by Bispecific Digoxigenin-binding Antibodies

por Schneider, Britta, Grote, Michael, John, Matthias, Haas, Alexander, Bramlage, Birgit, lckenstein, Ludger M, Jahn-Hofmann, Kerstin, Bauss, Frieder, Cheng, Weijun, Croasdale, Rebecca, Daub, Karin, Dill, Simone, Hoffmann, Eike, Lau, Wilma, Burtscher, Helmut, Ludtke, James L, Metz, Silke, Mundigl, Olaf, Neal, Zane C, Scheuer, Werner, Stracke, Jan, Herweijer, Hans, Brinkmann, Ulrjch
Publicado 2012