A narrative review of the evolving role of immunotherapy in the management of esophageal and gastric cancer

por Madan, Ankit, Uronis, Hope E., Strickler, John H.
Publicado 2022

Circulating Tumor DNA Testing Overcomes Limitations of Comprehensive Genomic Profiling from Tumor Tissue

por Kumar, Anivarya, Green, Michelle, Thacker, Julie, Jeck, William Richard, Strickler, John H.
Publicado 2023

Cell-Free DNA Profiling to Discover Mechanisms of Exceptional Response to Cabozantinib Plus Panitumumab in a Patient With Treatment Refractory Metastatic Colorectal Cancer

por Jia, Jingquan, Morse, Michael A., Nagy, Rebecca J., Lanman, Richard B., Strickler, John H.
Publicado 2018

Prevalence of KRAS G12C Mutation and Co-mutations and Associated Clinical Outcomes in Patients With Colorectal Cancer: A Systematic Literature Review

por Strickler, John H, Yoshino, Takayuki, Stevinson, Kendall, Eichinger, Christian Stefan, Giannopoulou, Christina, Rehn, Marko, Modest, Dominik Paul
Publicado 2023

Impact of Anti-EGFR Therapies on HER2-Positive Metastatic Colorectal Cancer: A Systematic Literature Review and Meta-Analysis of Clinical Outcomes

por Bekaii-Saab, Tanios S, Lach, Krzysztof, Hsu, Ling-I, Siadak, Muriel, Stecher, Mike, Ward, James, Beckerman, Rachel, Strickler, John H
Publicado 2023

Pharmacological Wnt ligand inhibition overcomes key tumor-mediated resistance pathways to anti-PD-1 immunotherapy

por DeVito, Nicholas C., Sturdivant, Michael, Thievanthiran, Balamayooran, Xiao, Christine, Plebanek, Michael P., Salama, April K.S., Beasley, Georgia M., Holtzhausen, Alisha, Novotny-Diermayr, Veronica, Strickler, John H., Hanks, Brent A.
Publicado 2021

Safety, Efficacy, and Biomarker Results from a Phase Ib Study of the Anti-DKK1 Antibody DKN-01 in Combination with Pembrolizumab in Advanced Esophagogastric Cancers

por Klempner, Samuel J., Bendell, Johanna C., Villaflor, Victoria Meucci, Tenner, Laura LaNiel, Stein, Stacey M., Rottman, James B., Naik, Girish S., Sirard, Cynthia A., Kagey, Michael H., Chaney, Marya F., Strickler, John H.
Publicado 2021

A phase 1 dose-escalation study of veliparib with bimonthly FOLFIRI in patients with advanced solid tumours

por Berlin, Jordan, Ramanathan, Ramesh K., Strickler, John H., Subramaniam, Deepa S., Marshall, John, Kang, Yoon-Koo, Hetman, Robert, Dudley, Matthew W., Zeng, Jiewei, Nickner, Caroline, Xiong, Hao, Komarnitsky, Philip, Shepherd, Stacie Peacock, Hurwitz, Herbert, Lenz, Heinz-Josef
Publicado 2018

Phase I Open-Label Study Evaluating the Safety, Pharmacokinetics, and Preliminary Efficacy of Dilpacimab in Patients with Advanced Solid Tumors

por Gordon, Michael S., Nemunaitis, John, Barve, Minal, Wainberg, Zev A., Hamilton, Erika P., Ramanathan, Ramesh K., Sledge, George W., Yue, Huibin, Morgan-Lappe, Susan E., Blaney, Martha, Kasichayanula, Sreeneeranj, Motwani, Monica, Wang, Lan, Naumovski, Louie, Strickler, John H.
Publicado 2021

Concordance Between Genomic Alterations Detected by Tumor and Germline Sequencing: Results from a Tertiary Care Academic Center Molecular Tumor Board

por Green, Michelle F, Watson, Catherine H, Tait, Sarah, He, Jie, Pavlick, Dean C, Frampton, Garrett, Riedel, Jinny, Plichta, Jennifer K, Armstrong, Andrew J, Previs, Rebecca A, Kauff, Noah, Strickler, John H, Datto, Michael B, Berchuck, Andrew, Menendez, Carolyn S
Publicado 2023

Phase I Study of 2- or 3-Week Dosing of Telisotuzumab Vedotin, an Antibody–Drug Conjugate Targeting c-Met, Monotherapy in Patients with Advanced Non–Small Cell Lung Carcinoma

por Camidge, D. Ross, Morgensztern, Daniel, Heist, Rebecca S., Barve, Minal, Vokes, Everett, Goldman, Jonathan W., Hong, David S., Bauer, Todd M., Strickler, John H., Angevin, Eric, Motwani, Monica, Parikh, Apurvasena, Sun, Zhaowen, Bach, Bruce Allen, Wu, Jun, Komarnitsky, Philip B., Kelly, Karen
Publicado 2021

Phase Ib Study of Telisotuzumab Vedotin in Combination With Erlotinib in Patients With c-Met Protein–Expressing Non–Small-Cell Lung Cancer

por Camidge, D. Ross, Barlesi, Fabrice, Goldman, Jonathan W., Morgensztern, Daniel, Heist, Rebecca, Vokes, Everett, Spira, Alex, Angevin, Eric, Su, Wu-Chou, Hong, David S., Strickler, John H., Motwani, Monica, Dunbar, Martin, Parikh, Apurvasena, Noon, Elysa, Blot, Vincent, Wu, Jun, Kelly, Karen
Publicado 2023

A phase Ib study of the combination regorafenib with PF-03446962 in patients with refractory metastatic colorectal cancer (REGAL-1 trial)

por Clarke, Jeffrey Melson, Blobe, Gerard C., Strickler, John H., Uronis, Hope Elizabeth, Zafar, S. Yousuf, Morse, Michael, Dropkin, Evan, Howard, Leigh, O’Neill, Margot, Rushing, Christel N., Niedzwiecki, Donna, Watson, Hollie, Bolch, Emily, Arrowood, Christy, Liu, Yingmiao, Nixon, Andrew B., Hurwitz, Herbert I.
Publicado 2019

Identification of an optimal mutant allele frequency to detect activating KRAS, NRAS, and BRAF mutations in a commercial cell-free DNA next-generation sequencing assay in colorecta...

por Caughey, Bennett A., Umemoto, Kumiko, Green, Michelle F., Ikeda, Masafumi, Lowe, Melissa E., Ueno, Makoto, Niedzwiecki, Donna, Taniguchi, Hiroya, Walden, Daniel J., Komatsu, Yoshito, D’Anna, Rachel, Esaki, Taito, Denda, Tadamichi, Datto, Michael B., Bando, Hideaki, Bekaii-Saab, Tanios, Yoshino, Takayuki, Strickler, John H., Nakamura, Yoshiaki
Publicado 2023

A phase Ib study of capecitabine and ziv-aflibercept followed by a phase II single-arm expansion cohort in chemotherapy refractory metastatic colorectal cancer

por Strickler, John H., Rushing, Christel N., Niedzwiecki, Donna, McLeod, Abigail, Altomare, Ivy, Uronis, Hope E., Hsu, S. David, Zafar, S. Yousuf, Morse, Michael A., Chang, David Z., Wells, James L., Blackwell, Kimberly L., Marcom, P. Kelly, Arrowood, Christy, Bolch, Emily, Haley, Sherri, Rangwala, Fatima A., Hatch, Ace J., Nixon, Andrew B., Hurwitz, Herbert I.
Publicado 2019

First-in-human study of oleclumab, a potent, selective anti-CD73 monoclonal antibody, alone or in combination with durvalumab in patients with advanced solid tumors

por Bendell, Johanna, LoRusso, Patricia, Overman, Michael, Noonan, Anne M., Kim, Dong-Wan, Strickler, John H., Kim, Sang-We, Clarke, Stephen, George, Thomas J., Grimison, Peter S., Barve, Minal, Amin, Manik, Desai, Jayesh, Wise-Draper, Trisha, Eck, Steven, Jiang, Yu, Khan, Anis A., Wu, Yuling, Martin, Philip, Cooper, Zachary A., Elgeioushi, Nairouz, Mueller, Nancy, Kumar, Rakesh, Patel, Sandip Pravin
Publicado 2023

Phase I study of anti-epidermal growth factor receptor antibody-drug conjugate serclutamab talirine: Safety, pharmacokinetics, and antitumor activity in advanced glioblastoma

por Carneiro, Benedito A, Papadopoulos, Kyriakos P, Strickler, John H, Lassman, Andrew B, Waqar, Saiama N, Chae, Young Kwang, Patel, Jyoti D, Shacham-Shmueli, Einat, Kelly, Karen, Khasraw, Mustafa, Bestvina, Christine M, Merrell, Ryan, Huang, Kevin, Atluri, Harisha, Ansell, Peter, Li, Rachel, Jin, Janet, Anderson, Mark G, Reilly, Edward B, Morrison-Thiele, Gladys, Patel, Kalpesh, Robinson, Randy R, Aristide, Martha R Neagu, Gan, Hui K
Publicado 2022

ctDNA applications and integration in colorectal cancer: an NCI Colon and Rectal–Anal Task Forces whitepaper

por Dasari, Arvind, Morris, Van K., Allegra, Carmen J., Atreya, Chloe, Benson, Al B., Boland, Patrick, Chung, Ki, Copur, Mehmet S., Corcoran, Ryan B., Deming, Dustin A., Dwyer, Andrea, Diehn, Maximilian, Eng, Cathy, George, Thomas J., Gollub, Marc J., Goodwin, Rachel A., Hamilton, Stanley R., Hechtman, Jaclyn F., Hochster, Howard, Hong, Theodore S., Innocenti, Federico, Iqbal, Atif, Jacobs, Samuel A., Kennecke, Hagen F., Lee, James J., Lieu, Christopher H., Lenz, Heinz-Josef, Lindwasser, O. Wolf, Montagut, Clara, Odisio, Bruno, Ou, Fang-Shu, Porter, Laura, Raghav, Kanwal, Schrag, Deborah, Scott, Aaron J., Shi, Qian, Strickler, John H., Venook, Alan, Yaeger, Rona, Yothers, Greg, You, Y. Nancy, Zell, Jason A., Kopetz, Scott
Publicado 2020