Ab initio molecular-replacement phasing for symmetric helical membrane proteins

por Strop, Pavel, Brzustowicz, Michael R., Brunger, Axel T.
Publicado 2007

Transglutaminase 2 Undergoes a Large Conformational Change upon Activation

por Pinkas, Daniel M, Strop, Pavel, Brunger, Axel T, Khosla, Chaitan
Publicado 2007

The Longin SNARE VAMP7/TI-VAMP Adopts a Closed Conformation

por Vivona, Sandro, Liu, Corey W., Strop, Pavel, Rossi, Valeria, Filippini, Francesco, Brunger, Axel T.
Publicado 2010

Single-molecule FRET-derived model of the synaptotagmin 1–SNARE fusion complex

por Choi, Ucheor B., Strop, Pavel, Vrljic, Marija, Chu, Steven, Brunger, Axel T., Weninger, Keith R.
Publicado 2010

Molecular mechanism of the synaptotagmin–SNARE interaction in Ca(2+)-triggered vesicle fusion

por Vrljic, Marija, Strop, Pavel, Ernst, James A., Sutton, R. Bryan, Chu, Steven, Brunger, Axel T.
Publicado 2010

Post-Translational Modifications and Lipid Binding Profile of Insect Cell-Expressed Full-Length Mammalian Synaptotagmin 1

por Vrljic, Marija, Strop, Pavel, Hill, Ryan C., Hansen, Kirk C., Chu, Steven, Brunger, Axel T.
Publicado 2011

World Antibody-Drug Conjugate Summit, October 15–16, 2013, San Francisco, CA

por Klinguer-Hamour, Christine, Strop, Pavel, Shah, Dhaval K, Ducry, Laurent, Xu, April, Beck, Alain
Publicado 2014

DPP6 Localization in Brain Supports Function as a Kv4 Channel Associated Protein

por Clark, Brian D., Kwon, Elaine, Maffie, Jon, Jeong, Hyo-Young, Nadal, Marcela, Strop, Pavel, Rudy, Bernardo
Publicado 2008

Antibodies Targeting Closely Adjacent or Minimally Overlapping Epitopes Can Displace One Another

por Abdiche, Yasmina Noubia, Yeung, Andy Yik, Ni, Irene, Stone, Donna, Miles, Adam, Morishige, Winse, Rossi, Andrea, Strop, Pavel
Publicado 2017

Antibody blockade of CD96 by distinct molecular mechanisms

por Lee, Peter S., Chau, Bryant, Barman, Ishita, Bee, Christine, Jashnani, Aarti, Hogan, Jason M., Aguilar, Barbara, Dollinger, Gavin, Rajpal, Arvind, Strop, Pavel
Publicado 2021

Biophysical characterization of PVR family interactions and therapeutic antibody recognition to TIGIT

por Diong, SJ J., Jashnani, Aarti, Drake, Andrew W., Bee, Christine, Findeisen, Felix, Dollinger, Gavin, Wang, Feng, Rajpal, Arvind, Strop, Pavel, Lee, Peter S.
Publicado 2023

Preclinical Characterization of Relatlimab, a Human LAG-3–Blocking Antibody, Alone or in Combination with Nivolumab

por Thudium, Kent, Selby, Mark, Zorn, Julie A., Rak, Gregory, Wang, Xi-Tao, Bunch, Roderick Todd, Hogan, Jason M., Strop, Pavel, Korman, Alan J.
Publicado 2022

Structures of mouse and human GITR–GITRL complexes reveal unique TNF superfamily interactions

por Wang, Feng, Chau, Bryant, West, Sean M., Kimberlin, Christopher R., Cao, Fei, Schwarz, Flavio, Aguilar, Barbara, Han, Minhua, Morishige, Winse, Bee, Christine, Dollinger, Gavin, Rajpal, Arvind, Strop, Pavel
Publicado 2021

The neonatal Fc receptor (FcRn) binds independently to both sites of the IgG homodimer with identical affinity

por Abdiche, Yasmina Noubia, Yeung, Yik Andy, Chaparro-Riggers, Javier, Barman, Ishita, Strop, Pavel, Chin, Sherman Michael, Pham, Amber, Bolton, Gary, McDonough, Dan, Lindquist, Kevin, Pons, Jaume, Rajpal, Arvind
Publicado 2015

RN765C, a low affinity EGFR antibody drug conjugate with potent anti-tumor activity in preclinical solid tumor models

por Wong, Oi Kwan, Tran, Thomas-Toan, Ho, Wei-Hsien, Casas, Meritxell Galindo, Au, Melinda, Bateman, Marjorie, Lindquist, Kevin C., Rajpal, Arvind, Shelton, David L., Strop, Pavel, Liu, Shu-Hui
Publicado 2018

Impact of Drug Conjugation on Thermal and Metabolic Stabilities of Aglycosylated and N-Glycosylated Antibodies

por Yamazoe, Sayumi, Kotapati, Srikanth, Hogan, Jason M., West, Sean M., Deng, Xiaodi A., Diong, SJ, Arbanas, Jaren, Nguyen, Thien Anh, Jashnani, Aarti, Gupta, Diksha, Rajpal, Arvind, Dollinger, Gavin, Strop, Pavel
Publicado 2022

The role of MscL amphipathic N terminus indicates a blueprint for bilayer-mediated gating of mechanosensitive channels

por Bavi, Navid, Cortes, D. Marien, Cox, Charles D., Rohde, Paul R., Liu, Weihong, Deitmer, Joachim W., Bavi, Omid, Strop, Pavel, Hill, Adam P., Rees, Douglas, Corry, Ben, Perozo, Eduardo, Martinac, Boris
Publicado 2016

Germline-encoded neutralization of a Staphylococcus aureus virulence factor by the human antibody repertoire

por Yeung, Yik Andy, Foletti, Davide, Deng, Xiaodi, Abdiche, Yasmina, Strop, Pavel, Glanville, Jacob, Pitts, Steven, Lindquist, Kevin, Sundar, Purnima D., Sirota, Marina, Hasa-Moreno, Adela, Pham, Amber, Melton Witt, Jody, Ni, Irene, Pons, Jaume, Shelton, David, Rajpal, Arvind, Chaparro-Riggers, Javier
Publicado 2016

Improved therapeutic index of an acidic pH-selective antibody

por Lee, Peter S., MacDonald, Katherine G., Massi, Evan, Chew, Pamela V., Bee, Christine, Perkins, Padma, Chau, Bryant, Thudium, Kent, Lohre, Jack, Nandi, Pradyot, Deyanova, Ekaterina G., Barman, Ishita, Gudmundsson, Olafur, Dollinger, Gavin, Sproul, Tim, Engelhardt, John J., Strop, Pavel, Rajpal, Arvind
Publicado 2022

Optimal design, anti-tumour efficacy and tolerability of anti-CXCR4 antibody drug conjugates

por Costa, Maria José, Kudaravalli, Jyothirmayee, Ma, Jing-Tyan, Ho, Wei-Hsien, Delaria, Kathy, Holz, Charles, Stauffer, Angela, Chunyk, Allison Given, Zong, Qing, Blasi, Eileen, Buetow, Bernard, Tran, Thomas-Toan, Lindquist, Kevin, Dorywalska, Magdalena, Rajpal, Arvind, Shelton, David L., Strop, Pavel, Liu, Shu-Hui
Publicado 2019