Constitutive XBP-1s-mediated activation of the endoplasmic reticulum unfolded protein response protects against pathological tau

por Waldherr, Sarah M., Strovas, Timothy J., Vadset, Taylor A., Liachko, Nicole F., Kraemer, Brian C.
Publicado 2019

Genome wide analysis reveals heparan sulfate epimerase modulates TDP-43 proteinopathy

por Liachko, Nicole F., Saxton, Aleen D., McMillan, Pamela J., Strovas, Timothy J., Keene, C. Dirk, Bird, Thomas D., Kraemer, Brian C.
Publicado 2019

Pathological phosphorylation of tau and TDP-43 by TTBK1 and TTBK2 drives neurodegeneration

por Taylor, Laura M., McMillan, Pamela J., Liachko, Nicole F., Strovas, Timothy J., Ghetti, Bernardino, Bird, Thomas D., Keene, C. Dirk, Kraemer, Brian C.
Publicado 2018

Distinct Poly(A) nucleases have differential impact on sut-2 dependent tauopathy phenotypes.

por Kow, Rebecca L., Strovas, Timothy J., McMillan, Pamela J., Jacobi, Ashley M., Behlke, Mark A., Saxton, Aleen D., Latimer, Caitlin S., Keene, C. Dirk, Kraemer, Brian C.
Publicado 2020

Pathological tau drives ectopic nuclear speckle scaffold protein SRRM2 accumulation in neuron cytoplasm in Alzheimer’s disease

por McMillan, Pamela J., Strovas, Timothy J., Baum, Misa, Mitchell, Brooke K., Eck, Randall J., Hendricks, Nzinga, Wheeler, Jeanna M., Latimer, Caitlin S., Keene, C. Dirk, Kraemer, Brian C.
Publicado 2021

The Tau Tubulin Kinases TTBK1/2 Promote Accumulation of Pathological TDP-43

por Liachko, Nicole F., McMillan, Pamela J., Strovas, Timothy J., Loomis, Elaine, Greenup, Lynne, Murrell, Jill R., Ghetti, Bernardino, Raskind, Murray A., Montine, Thomas J., Bird, Thomas D., Leverenz, James B., Kraemer, Brian C.
Publicado 2014