Paving the Way to Understand Autoantibody-Mediated Epilepsy on the Molecular Level

por Seebohm, Guiscard, Piccini, Ilaria, Strutz-Seebohm, Nathalie
Publicado 2015

Klotho:  A new trafficking modifier of Kv7.1/KCNE1 channels

por Strutz-Seebohm, Nathalie, Wrobel, Eva, Schulze-Bahr, Eric, Seebohm, Guiscard
Publicado 2014

Pharmacological Potential of 3-Benzazepines in NMDAR-Linked Pathophysiological Processes

por Ritter, Nadine, Disse, Paul, Wünsch, Bernhard, Seebohm, Guiscard, Strutz-Seebohm, Nathalie
Publicado 2023

From iPSC towards cardiac tissue—a road under construction

por Peischard, Stefan, Piccini, Ilaria, Strutz-Seebohm, Nathalie, Greber, Boris, Seebohm, Guiscard
Publicado 2017

Myocardial Damage by SARS-CoV-2: Emerging Mechanisms and Therapies

por Ho, Huyen Tran, Peischard, Stefan, Strutz-Seebohm, Nathalie, Klingel, Karin, Seebohm, Guiscard
Publicado 2021

NDRG2 phosphorylation provides negative feedback for SGK1-dependent regulation of a kainate receptor in astrocytes

por Matschke, Veronika, Theiss, Carsten, Hollmann, Michael, Schulze-Bahr, Eric, Lang, Florian, Seebohm, Guiscard, Strutz-Seebohm, Nathalie
Publicado 2015

Knockout of the Cardiac Transcription Factor NKX2-5 Results in Stem Cell-Derived Cardiac Cells with Typical Purkinje Cell-like Signal Transduction and Extracellular Matrix Formatio...

por Disse, Paul, Aymanns, Isabel, Mücher, Lena, Sandmann, Sarah, Varghese, Julian, Ritter, Nadine, Strutz-Seebohm, Nathalie, Seebohm, Guiscard, Peischard, Stefan
Publicado 2023

Structural interplay of K(V)7.1 and KCNE1 is essential for normal repolarization and is compromised in short QT syndrome 2 (K(V)7.1-A287T)

por Rothenberg, Ina, Piccini, Ilaria, Wrobel, Eva, Stallmeyer, Birgit, Müller, Jovanca, Greber, Boris, Strutz-Seebohm, Nathalie, Schulze-Bahr, Eric, Schmitt, Nicole, Seebohm, Guiscard
Publicado 2016

A common mechanism allows selective targeting of GluN2B subunit-containing N-methyl-D-aspartate receptors

por Schreiber, Julian A., Schepmann, Dirk, Frehland, Bastian, Thum, Simone, Datunashvili, Maia, Budde, Thomas, Hollmann, Michael, Strutz-Seebohm, Nathalie, Wünsch, Bernhard, Seebohm, Guiscard
Publicado 2019

Identification of a Novel Signaling Pathway and Its Relevance for GluA1 Recycling

por Seebohm, Guiscard, Neumann, Sebastian, Theiss, Carsten, Novkovic, Tanja, Hill, Elaine V., Tavaré, Jeremy M., Lang, Florian, Hollmann, Michael, Manahan-Vaughan, Denise, Strutz-Seebohm, Nathalie
Publicado 2012

Rottlerin: Structure Modifications and KCNQ1/KCNE1 Ion Channel Activity

por Lübke, Marco, Schreiber, Julian A., Le Quoc, Thang, Körber, Florian, Müller, Jasmin, Sivanathan, Sivatharushan, Matschke, Veronika, Schubert, Janina, Strutz‐Seebohm, Nathalie, Seebohm, Guiscard, Scherkenbeck, Jürgen
Publicado 2020

Cloxyquin activates hTRESK by allosteric modulation of the selectivity filter

por Schreiber, Julian Alexander, Derksen, Anastasia, Goerges, Gunnar, Schütte, Sven, Sörgel, Jasmin, Kiper, Aytug K., Strutz-Seebohm, Nathalie, Ruck, Tobias, Meuth, Sven G., Decher, Niels, Seebohm, Guiscard
Publicado 2023

Downstream Allosteric Modulation of NMDA Receptors by 3-Benzazepine Derivatives

por Ritter, Nadine, Disse, Paul, Aymanns, Isabel, Mücher, Lena, Schreiber, Julian A., Brenker, Christoph, Strünker, Timo, Schepmann, Dirk, Budde, Thomas, Strutz-Seebohm, Nathalie, Ametamey, Simon M., Wünsch, Bernhard, Seebohm, Guiscard
Publicado 2023

Structural basis of PI(4,5)P(2)-dependent regulation of GluA1 by phosphatidylinositol-5-phosphate 4-kinase, type II, alpha (PIP5K2A)

por Seebohm, Guiscard, Wrobel, Eva, Pusch, Michael, Dicks, Markus, Terhag, Jan, Matschke, Veronika, Rothenberg, Ina, Ursu, Oana N., Hertel, Fabian, Pott, Lutz, Lang, Florian, Schulze-Bahr, Eric, Hollmann, Michael, Stoll, Raphael, Strutz-Seebohm, Nathalie
Publicado 2014

Virus-induced inhibition of cardiac pacemaker channel HCN4 triggers bradycardia in human-induced stem cell system

por Peischard, Stefan, Möller, Melina, Disse, Paul, Ho, Huyen Tran, Verkerk, Arie O., Strutz-Seebohm, Nathalie, Budde, Thomas, Meuth, Sven G., Schweizer, Patrick A., Morris, Silke, Mücher, Lena, Eisner, Verónica, Thomas, Dierk, Klingel, Karin, Busch, Karin, Seebohm, Guiscard
Publicado 2022

The first versatile human iPSC-based model of ectopic virus induction allows new insights in RNA-virus disease

por Peischard, Stefan, Ho, Huyen Tran, Piccini, Ilaria, Strutz-Seebohm, Nathalie, Röpke, Albrecht, Liashkovich, Ivan, Gosain, Hiteshika, Rieger, Bettina, Klingel, Karin, Eggers, Britta, Marcus, Katrin, Linke, Wolfgang A., Müller, Frank Ulrich, Ludwig, Stephan, Greber, Boris, Busch, Karin, Seebohm, Guiscard
Publicado 2020

KCNE1 induces fenestration in the Kv7.1/KCNE1 channel complex that allows for highly specific pharmacological targeting

por Wrobel, Eva, Rothenberg, Ina, Krisp, Christoph, Hundt, Franziska, Fraenzel, Benjamin, Eckey, Karina, Linders, Joannes T. M., Gallacher, David J., Towart, Rob, Pott, Lutz, Pusch, Michael, Yang, Tao, Roden, Dan M., Kurata, Harley T., Schulze-Bahr, Eric, Strutz-Seebohm, Nathalie, Wolters, Dirk, Seebohm, Guiscard
Publicado 2016

An Assay to Determine Mechanisms of Rapid Autoantibody-Induced Neurotransmitter Receptor Endocytosis and Vesicular Trafficking in Autoimmune Encephalitis

por Amedonu, Elsie, Brenker, Christoph, Barman, Sumanta, Schreiber, Julian A., Becker, Sebastian, Peischard, Stefan, Strutz-Seebohm, Nathalie, Strippel, Christine, Dik, Andre, Hartung, Hans-Peter, Budde, Thomas, Wiendl, Heinz, Strünker, Timo, Wünsch, Bernhard, Goebels, Norbert, Meuth, Sven G., Seebohm, Guiscard, Melzer, Nico
Publicado 2019

A benzodiazepine activator locks K(v)7.1 channels open by electro-mechanical uncoupling

por Schreiber, Julian A., Möller, Melina, Zaydman, Mark, Zhao, Lu, Beller, Zachary, Becker, Sebastian, Ritter, Nadine, Hou, Panpan, Shi, Jingyi, Silva, Jon, Wrobel, Eva, Strutz-Seebohm, Nathalie, Decher, Niels, Schmitt, Nicole, Meuth, Sven G., Düfer, Martina, Wünsch, Bernhard, Cui, Jianmin, Seebohm, Guiscard
Publicado 2022

Pathophysiological Mechanisms of Cardiac Dysfunction in Transgenic Mice with Viral Myocarditis

por Rohrbeck, Matthias, Hoerr, Verena, Piccini, Ilaria, Greber, Boris, Schulte, Jan Sebastian, Hübner, Sara-Sophie, Jeworutzki, Elena, Theiss, Carsten, Matschke, Veronika, Stypmann, Jörg, Unger, Andreas, Ho, Huyen Tran, Disse, Paul, Strutz-Seebohm, Nathalie, Faber, Cornelius, Müller, Frank Ulrich, Ludwig, Stephan, Rescher, Ursula, Linke, Wolfgang A., Klingel, Karin, Busch, Karin, Peischard, Stefan, Seebohm, Guiscard
Publicado 2023