A human receptor occupancy assay to measure anti‐PD‐1 binding in patients with prior anti‐PD‐1

por Junker, Fabian, Gulati, Pratiksha, Wessels, Uwe, Seeber, Stefan, Stubenrauch, Kay‐Gunnar, Codarri‐Deak, Laura, Markert, Christoph, Klein, Christian, Camillo Teixeira, Priscila, Kao, Henry
Publicado 2021

Hapten-directed spontaneous disulfide shuffling: a universal technology for site-directed covalent coupling of payloads to antibodies

por Dengl, Stefan, Hoffmann, Eike, Grote, Michael, Wagner, Cornelia, Mundigl, Olaf, Georges, Guy, Thorey, Irmgard, Stubenrauch, Kay-Gunnar, Bujotzek, Alexander, Josel, Hans-Peter, Dziadek, Sebastian, Benz, Joerg, Brinkmann, Ulrich
Publicado 2015

Chimeric antigen receptor T cells engineered to recognize the P329G-mutated Fc part of effector-silenced tumor antigen-targeting human IgG1 antibodies enable modular targeting of s...

por Stock, Sophia, Benmebarek, Mohamed-Reda, Kluever, Anna-Kristina, Darowski, Diana, Jost, Christian, Stubenrauch, Kay-Gunnar, Benz, Joerg, Freimoser-Grundschober, Anne, Moessner, Ekkehard, Umana, Pablo, Subklewe, Marion, Endres, Stefan, Klein, Christian, Kobold, Sebastian
Publicado 2022

Prodrug-Activating Chain Exchange (PACE) converts targeted prodrug derivatives to functional bi- or multispecific antibodies

por Dickopf, Steffen, Buldun, Can, Vasic, Vedran, Georges, Guy, Hage, Carina, Mayer, Klaus, Forster, Matthias, Wessels, Uwe, Stubenrauch, Kay-Gunnar, Benz, Jörg, Ehler, Andreas, Lauer, Matthias E., Ringler, Philippe, Kobold, Sebastian, Endres, Stefan, Klein, Christian, Brinkmann, Ulrich
Publicado 2022

Protease-activation using anti-idiotypic masks enables tumor specificity of a folate receptor 1-T cell bispecific antibody

por Geiger, Martina, Stubenrauch, Kay-Gunnar, Sam, Johannes, Richter, Wolfgang F., Jordan, Gregor, Eckmann, Jan, Hage, Carina, Nicolini, Valeria, Freimoser-Grundschober, Anne, Ritter, Mirko, Lauer, Matthias E., Stahlberg, Henning, Ringler, Philippe, Patel, Jigar, Sullivan, Eric, Grau-Richards, Sandra, Endres, Stefan, Kobold, Sebastian, Umaña, Pablo, Brünker, Peter, Klein, Christian
Publicado 2020

Immunogenicity assessment of AAV-based gene therapies: An IQ consortium industry white paper

por Yang, Tong-yuan, Braun, Manuela, Lembke, Wibke, McBlane, Fraser, Kamerud, John, DeWall, Stephen, Tarcsa, Edit, Fang, Xiaodong, Hofer, Lena, Kavita, Uma, Upreti, Vijay V., Gupta, Swati, Loo, LiNa, Johnson, Alison J., Chandode, Rakesh Kantilal, Stubenrauch, Kay-Gunnar, Vinzing, Maya, Xia, Cindy Q., Jawa, Vibha
Publicado 2022