Is Receptor-Interacting Protein Kinase 3 a Viable Therapeutic Target for Mycobacterium tuberculosis Infection?

por Stutz, Michael D., Ojaimi, Samar, Ebert, Gregor, Pellegrini, Marc
Publicado 2018

Mycobacterium tuberculosis: Rewiring host cell signaling to promote infection

por Stutz, Michael D., Clark, Michelle P., Doerflinger, Marcel, Pellegrini, Marc
Publicado 2017

Variant repeats are interspersed throughout the telomeres and recruit nuclear receptors in ALT cells

por Conomos, Dimitri, Stutz, Michael D., Hills, Mark, Neumann, Axel A., Bryan, Tracy M., Reddel, Roger R., Pickett, Hilda A.
Publicado 2012

Telomere extension by telomerase and ALT generates variant repeats by mechanistically distinct processes

por Lee, Michael, Hills, Mark, Conomos, Dimitri, Stutz, Michael D., Dagg, Rebecca A., Lau, Loretta M.S., Reddel, Roger R., Pickett, Hilda A.
Publicado 2014

A Common Cancer Risk-Associated Allele in the hTERT Locus Encodes a Dominant Negative Inhibitor of Telomerase

por Killedar, Anagha, Stutz, Michael D., Sobinoff, Alexander P., Tomlinson, Christopher G., Bryan, Tracy M., Beesley, Jonathan, Chenevix-Trench, Georgia, Reddel, Roger R., Pickett, Hilda A.
Publicado 2015

Constitutive overexpression of TNF in BPSM1 mice causes iBALT and bone marrow nodular lymphocytic hyperplasia

por Seillet, Cyril, Arvell, Elyas H, Lacey, Derek, Stutz, Michael D, Pellegrini, Marc, Whitehead, Lachlan, Rimes, Joel, Hawkins, Edwin D, Roediger, Ben, Belz, Gabrielle T, Bouillet, Philippe
Publicado 2018

Necroptotic signaling is primed in Mycobacterium tuberculosis-infected macrophages, but its pathophysiological consequence in disease is restricted

por Stutz, Michael D., Ojaimi, Samar, Allison, Cody, Preston, Simon, Arandjelovic, Philip, Hildebrand, Joanne M., Sandow, Jarrod J., Webb, Andrew I., Silke, John, Alexander, Warren S., Pellegrini, Marc
Publicado 2017

Clinical stage drugs targeting inhibitor of apoptosis proteins purge episomal Hepatitis B viral genome in preclinical models

por Clark, Michelle P., Huynh, Thao, Rao, Shringar, Mackiewicz, Liana, Mason, Hugh, Romal, Shahla, Stutz, Michael D., Ahn, Sang H., Earnest, Linda, Sozzi, Vitina, Littlejohn, Margaret, Tran, Bang M., Wiedemann, Norbert, Vincan, Elizabeth, Torresi, Joseph, Netter, Hans J., Mahmoudi, Tokameh, Revill, Peter, Pellegrini, Marc, Ebert, Gregor
Publicado 2021

Mpeg1 is not essential for antibacterial or antiviral immunity, but is implicated in antigen presentation

por Ebrahimnezhaddarzi, Salimeh, Bird, Catherina H, Allison, Cody C, Tuipulotu, Daniel E, Kostoulias, Xenia, Macri, Christophe, Stutz, Michael D, Abraham, Gilu, Kaiserman, Dion, Pang, Siew Siew, Man, Si Ming, Mintern, Justine D, Naderer, Thomas, Peleg, Anton Y, Pellegrini, Marc, Whisstock, James C, Bird, Phillip I
Publicado 2022

Endothelial Caspase-8 prevents fatal necroptotic hemorrhage caused by commensal bacteria

por Bader, Stefanie M., Preston, Simon P., Saliba, Katie, Lipszyc, Adam, Grant, Zoe L., Mackiewicz, Liana, Baldi, Andrew, Hempel, Anne, Clark, Michelle P., Peiris, Thanushi, Clow, William, Bjelic, Jan, Stutz, Michael D., Arandjelovic, Philip, Teale, Jack, Du, Fashuo, Coultas, Leigh, Murphy, James M., Allison, Cody C., Pellegrini, Marc, Samson, Andre L.
Publicado 2022

Functional Polymorphisms in the TERT Promoter Are Associated with Risk of Serous Epithelial Ovarian and Breast Cancers

por Beesley, Jonathan, Pickett, Hilda A., Johnatty, Sharon E., Dunning, Alison M., Chen, Xiaoqing, Li, Jun, Michailidou, Kyriaki, Lu, Yi, Rider, David N., Palmieri, Rachel T., Stutz, Michael D., Lambrechts, Diether, Despierre, Evelyn, Lambrechts, Sandrina, Vergote, Ignace, Chang-Claude, Jenny, Nickels, Stefan, Vrieling, Alina, Flesch-Janys, Dieter, Wang-Gohrke, Shan, Eilber, Ursula, Bogdanova, Natalia, Antonenkova, Natalia, Runnebaum, Ingo B., Dörk, Thilo, Goodman, Marc T., Lurie, Galina, Wilkens, Lynne R., Matsuno, Rayna K., Kiemeney, Lambertus A., Aben, Katja K. H., Marees, Tamara, Massuger, Leon F. A. G., Fridley, Brooke L., Vierkant, Robert A., Bandera, Elisa V., Olson, Sara H., Orlow, Irene, Rodriguez-Rodriguez, Lorna, Cook, Linda S., Le, Nhu D., Brooks-Wilson, Angela, Kelemen, Linda E., Campbell, Ian, Gayther, Simon A., Ramus, Susan J., Gentry-Maharaj, Aleksandra, Menon, Usha, Ahmed, Shahana, Baynes, Caroline, Pharoah, Paul D., Investigators, kConFab, Muir, Kenneth, Lophatananon, Artitaya, Chaiwerawattana, Arkom, Wiangnon, Surapon, Macgregor, Stuart, Easton, Douglas F., Reddel, Roger R., Goode, Ellen L., Chenevix-Trench, Georgia
Publicado 2011

A missense mutation in the MLKL brace region promotes lethal neonatal inflammation and hematopoietic dysfunction

por Hildebrand, Joanne M., Kauppi, Maria, Majewski, Ian J., Liu, Zikou, Cox, Allison J., Miyake, Sanae, Petrie, Emma J., Silk, Michael A., Li, Zhixiu, Tanzer, Maria C., Brumatti, Gabriela, Young, Samuel N., Hall, Cathrine, Garnish, Sarah E., Corbin, Jason, Stutz, Michael D., Di Rago, Ladina, Gangatirkar, Pradnya, Josefsson, Emma C., Rigbye, Kristin, Anderton, Holly, Rickard, James A., Tripaydonis, Anne, Sheridan, Julie, Scerri, Thomas S., Jackson, Victoria E., Czabotar, Peter E., Zhang, Jian-Guo, Varghese, Leila, Allison, Cody C., Pellegrini, Marc, Tannahill, Gillian M., Hatchell, Esme C., Willson, Tracy A., Stockwell, Dina, de Graaf, Carolyn A., Collinge, Janelle, Hilton, Adrienne, Silke, Natasha, Spall, Sukhdeep K., Chau, Diep, Athanasopoulos, Vicki, Metcalf, Donald, Laxer, Ronald M., Bassuk, Alexander G., Darbro, Benjamin W., Fiatarone Singh, Maria A., Vlahovich, Nicole, Hughes, David, Kozlovskaia, Maria, Ascher, David B., Warnatz, Klaus, Venhoff, Nils, Thiel, Jens, Biben, Christine, Blum, Stefan, Reveille, John, Hildebrand, Michael S., Vinuesa, Carola G., McCombe, Pamela, Brown, Matthew A., Kile, Benjamin T., McLean, Catriona, Bahlo, Melanie, Masters, Seth L., Nakano, Hiroyasu, Ferguson, Polly J., Murphy, James M., Alexander, Warren S., Silke, John
Publicado 2020