miRNA Alterations Modify Kinase Activation In The IGF-1 Pathway And Correlate With Colorectal Cancer Stage And Progression In Patients

por Knowlton, David L., Tang, Kim, Henstock, Peter V., Subramanian, Romesh R.
Publicado 2011

mRNA treatment produces sustained expression of enzymatically active human ADAMTS13 in mice

por Liu-Chen, Susan, Connolly, Brendan, Cheng, Lei, Subramanian, Romesh R., Han, Zhaozhong
Publicado 2018

SERPINA1 mRNA as a Treatment for Alpha-1 Antitrypsin Deficiency

por Connolly, Brendan, Isaacs, Cleo, Cheng, Lei, Asrani, Kirtika H., Subramanian, Romesh R.
Publicado 2018

G6PC mRNA Therapy Positively Regulates Fasting Blood Glucose and Decreases Liver Abnormalities in a Mouse Model of Glycogen Storage Disease 1a

por Roseman, Daniel S., Khan, Tayeba, Rajas, Fabienne, Jun, Lucy S., Asrani, Kirtika H., Isaacs, Cleo, Farelli, Jeremiah D., Subramanian, Romesh R.
Publicado 2018

Optimization of mRNA untranslated regions for improved expression of therapeutic mRNA

por Asrani, Kirtika H., Farelli, Jeremiah D., Stahley, Mary R., Miller, Rebecca L., Cheng, Christopher J., Subramanian, Romesh R., Brown, Jeffrey M.
Publicado 2018

siRNA Off-Target Effects Can Be Reduced at Concentrations That Match Their Individual Potency

por Caffrey, Daniel R., Zhao, Juan, Song, Zhili, Schaffer, Michael E., Haney, Steven A., Subramanian, Romesh R., Seymour, Albert B., Hughes, Jason D.
Publicado 2011

Enhancing antisense efficacy with multimers and multi-targeting oligonucleotides (MTOs) using cleavable linkers

por Subramanian, Romesh R., Wysk, Mark A., Ogilvie, Kathleen M., Bhat, Abhijit, Kuang, Bing, Rockel, Thomas D., Weber, Markus, Uhlmann, Eugen, Krieg, Arthur M.
Publicado 2015