Structural and Biophysical Characterization of Stable Alpha-Synuclein Oligomers

por Vaikath, Nishant, Sudhakaran, Indulekha, Abdi, Ilham, Gupta, Vijay, Majbour, Nour, Ghanem, Simona, Abdesselem, Houari, Vekrellis, Kostas, El-Agnaf, Omar
Publicado 2022

Expression, purification and characterization of α-synuclein fibrillar specific scFv from inclusion bodies

por Gupta, Vijay, Sudhakaran, Indulekha P., Islam, Zeyaul, Vaikath, Nishant N., Hmila, Issam, Lukacsovich, Tamas, Kolatkar, Prasanna R., El-Agnaf, Omar M. A.
Publicado 2020

Investigating the presence of doubly phosphorylated α‐synuclein at tyrosine 125 and serine 129 in idiopathic Lewy body diseases

por Fayyad, Muneera, Erskine, Daniel, Majbour, Nour K., Vaikath, Nishant N., Ghanem, Simona S., Sudhakaran, Indulekha P., Abdesselem, Houari, Lamprokostopoulou, Agaristi, Vekrellis, Kostas, Morris, Christopher M., Attems, Johannes, El‐Agnaf, Omar M. A.
Publicado 2020

Fibrillar form of α-synuclein-specific scFv antibody inhibits α-synuclein seeds induced aggregation and toxicity

por Gupta, Vijay, Salim, Safa, Hmila, Issam, Vaikath, Nishant N., Sudhakaran, Indulekha P., Ghanem, Simona S., Majbour, Nour K., Abdulla, Sara A., Emara, Mohamed M., Abdesselem, Houari B., Lukacsovich, Tamas, Erskine, Daniel, El-Agnaf, Omar M. A.
Publicado 2020

Novel engineered nanobodies specific for N‐terminal region of alpha‐synuclein recognize Lewy‐body pathology and inhibit in‐vitro seeded aggregation and toxicity

por Hmila, Issam, Vaikath, Nishant N., Majbour, Nour K., Erskine, Daniel, Sudhakaran, Indulekha P., Gupta, Vijay, Ghanem, Simona S., Islam, Zeyaul, Emara, Mohamed M., Abdesselem, Houari B., Kolatkar, Prasanna R., Achappa, Devaya K., Vinardell, Tatiana, El‐Agnaf, Omar M. A.
Publicado 2022

α-Synuclein phosphorylation at serine 129 occurs after initial protein deposition and inhibits seeded fibril formation and toxicity

por Ghanem, Simona S., Majbour, Nour K., Vaikath, Nishant N., Ardah, Mustafa T., Erskine, Daniel, Jensen, Nanna Møller, Fayyad, Muneera, Sudhakaran, Indulekha P., Vasili, Eftychia, Melachroinou, Katerina, Abdi, Ilham Y., Poggiolini, Ilaria, Santos, Patricia, Dorn, Anton, Carloni, Paolo, Vekrellis, Kostas, Attems, Johannes, McKeith, Ian, Outeiro, Tiago F., Jensen, Poul Henning, El-Agnaf, Omar M. A.
Publicado 2022