Sodium–glucose cotransporter 2 inhibitor, tofogliflozin, shows better improvements of blood glucose and insulin secretion in patients with high insulin levels at baseline

por Tobe, Kazuyuki, Suganami, Hideki, Kaku, Kohei
Publicado 2017

Morphological Changes of Human Corneal Endothelial Cells after Rho-Associated Kinase Inhibitor Eye Drop (Ripasudil) Administration: A Prospective Open-Label Clinical Study

por Nakagawa, Hiroko, Koizumi, Noriko, Okumura, Naoki, Suganami, Hideki, Kinoshita, Shigeru
Publicado 2015

Effects of sodium‐glucose cotransporter 2 inhibitor, tofogliflozin, on the indices of renal tubular function in patients with type 2 diabetes

por Nunoi, Kiyohide, Sato, Yuichi, Kaku, Kohei, Yoshida, Akihiro, Suganami, Hideki
Publicado 2018

Renal effects of a sodium‐glucose cotransporter 2 inhibitor, tofogliflozin, in relation to sodium intake and glycaemic status

por Nunoi, Kiyohide, Sato, Yuichi, Kaku, Kohei, Yoshida, Akihiro, Suganami, Hideki
Publicado 2019

Basal insulin secretion capacity predicts the initial response and maximum levels of beta‐hydroxybutyrate during therapy with the sodium‐glucose co‐transporter‐2 inhibitor tofoglif...

por Sato, Yuichi, Nunoi, Kiyohide, Kaku, Kohei, Yoshida, Akihiro, Suganami, Hideki
Publicado 2019

Efficacy and Safety of Pitavastatin/Ezetimibe Fixed-Dose Combination vs. Pitavastatin: Phase III, Double-Blind, Randomized Controlled Trial

por Tsujita, Kenichi, Yokote, Koutaro, Ako, Junya, Tanigawa, Ryohei, Tajima, Sachiko, Suganami, Hideki
Publicado 2023

Efficacy and Safety of Pemafibrate Versus Fenofibrate in Patients with High Triglyceride and Low HDL Cholesterol Levels: A Multicenter, Placebo-Controlled, Double-Blind, Randomized...

por Arai, Hidenori, Yamashita, Shizuya, Yokote, Koutaro, Araki, Eiichi, Suganami, Hideki, Ishibashi, Shun
Publicado 2018

Long-Term Efficacy and Safety of Pemafibrate, a Novel Selective Peroxisome Proliferator-Activated Receptor-α Modulator (SPPARMα), in Dyslipidemic Patients with Renal Impairment

por Yokote, Koutaro, Yamashita, Shizuya, Arai, Hidenori, Araki, Eiichi, Suganami, Hideki, Ishibashi, Shun
Publicado 2019

Effects of a novel selective peroxisome proliferator‐activated receptor‐α modulator, pemafibrate, on hepatic and peripheral glucose uptake in patients with hypertriglyceridemia and...

por Matsuba, Ikuro, Matsuba, Ren, Ishibashi, Shun, Yamashita, Shizuya, Arai, Hidenori, Yokote, Koutaro, Suganami, Hideki, Araki, Eiichi
Publicado 2018

Long‐term safety and efficacy of the sodium–glucose cotransporter 2 inhibitor, tofogliflozin, added on glucagon‐like peptide‐1 receptor agonist in Japanese patients with type 2 dia...

por Terauchi, Yasuo, Fujiwara, Hisataka, Kurihara, Yuji, Suganami, Hideki, Tamura, Masahiro, Senda, Masayuki, Gunji, Ryoji, Kaku, Kohei
Publicado 2019

Efficacy and Safety of Pemafibrate, a Novel Selective Peroxisome Proliferator-Activated Receptor α Modulator (SPPARMα): Pooled Analysis of Phase 2 and 3 Studies in Dyslipidemic Pat...

por Yamashita, Shizuya, Arai, Hidenori, Yokote, Koutaro, Araki, Eiichi, Matsushita, Mitsunori, Nojima, Toshiaki, Suganami, Hideki, Ishibashi, Shun
Publicado 2019

Effects of pemafibrate on glucose metabolism markers and liver function tests in patients with hypertriglyceridemia: a pooled analysis of six phase 2 and phase 3 randomized double‐...

por Yokote, Koutaro, Yamashita, Shizuya, Arai, Hidenori, Araki, Eiichi, Matsushita, Mitsunori, Nojima, Toshiaki, Suganami, Hideki, Ishibashi, Shun
Publicado 2021

Crossover Randomized Study of Pharmacologic Effects of Ripasudil–Brimonidine Fixed-Dose Combination Versus Ripasudil or Brimonidine

por Tanihara, Hidenobu, Yamamoto, Tetsuya, Aihara, Makoto, Koizumi, Noriko, Minami, Hiroomi, Kojima, Satoshi, Isobe, Tomoyuki, Kanazawa, Mizuho, Suganami, Hideki
Publicado 2023

Evaluation of Data Errors and Monitoring Activities in a Trial in Japan Using a Risk-Based Approach Including Central Monitoring and Site Risk Assessment

por Kondo, Hidenobu, Kamiyoshihara, Tomoaki, Fujisawa, Kenji, Nojima, Toshiaki, Tanigawa, Ryohei, Fujiwara, Hisataka, Suganami, Hideki, Hayashi, Yukikazu, Yamaguchi, Takuhiro
Publicado 2021

Association of increased hepatic insulin clearance and change in serum triglycerides or β‐hydroxybutyrate concentration via the sodium/glucose‐cotransporter 2 inhibitor tofoglifloz...

por Matsubayashi, Yasuhiro, Yoshida, Akihiro, Suganami, Hideki, Osawa, Taeko, Furukawa, Kazuo, Suzuki, Hiroshi, Fujihara, Kazuya, Tanaka, Shiro, Kaku, Kohei, Sone, Hirohito
Publicado 2020

Dipeptidyl peptidase‐4 inhibitor, anagliptin, alters hepatic insulin clearance in relation to the glycemic status in Japanese individuals with type 2 diabetes

por Abe, Takahiro, Matsubayashi, Yasuhiro, Muragishi, Sayaka, Yoshida, Akihiro, Suganami, Hideki, Furusawa, Kenichi, Fujihara, Kazuya, Tanaka, Shiro, Kaku, Kohei, Sone, Hirohito
Publicado 2021

Efficacy and safety of monotherapy with the novel sodium/glucose cotransporter-2 inhibitor tofogliflozin in Japanese patients with type 2 diabetes mellitus: a combined Phase 2 and...

por Kaku, Kohei, Watada, Hirotaka, Iwamoto, Yasuhiko, Utsunomiya, Kazunori, Terauchi, Yasuo, Tobe, Kazuyuki, Tanizawa, Yukio, Araki, Eiichi, Ueda, Masamichi, Suganami, Hideki, Watanabe, Daisuke
Publicado 2014

Association of estimated plasma volume and weight loss after long‐term administration and subsequent discontinuation of the sodium‐glucose cotransporter‐2 inhibitor tofogliflozin...

por Matsubayashi, Yasuhiro, Yoshida, Akihiro, Suganami, Hideki, Oe, Momoko, Sato, Takaaki, Yaguchi, Yuta, Fujihara, Kazuya, Yamada, Takaho, Tanaka, Shiro, Kaku, Kohei, Sone, Hirohito
Publicado 2021

Randomised clinical trial: Pemafibrate, a novel selective peroxisome proliferator‐activated receptor α modulator (SPPARMα), versus placebo in patients with non‐alcoholic fatty live...

por Nakajima, Atsushi, Eguchi, Yuichiro, Yoneda, Masato, Imajo, Kento, Tamaki, Nobuharu, Suganami, Hideki, Nojima, Toshiaki, Tanigawa, Ryohei, Iizuka, Masakazu, Iida, Yuki, Loomba, Rohit
Publicado 2021

Predictors of haemoglobin levels and of changes in these levels, focusing on anaemia and polycythaemia after administration of the sodium‐glucose cotransporter‐2 inhibitor tofoglif...

por Matsubayashi, Yasuhiro, Yoshida, Alkihiro, Suganami, Hideki, Oe, Momoko, Sato, Takaaki, Yaguchi, Yuta, Fujihara, Kazuya, Yamada, Takaho, Tanaka, Shiro, Kaku, Kohei, Sone, Hirohito
Publicado 2022