Recombinant Human PH20: Baseline Analysis of the Reactive Antibody Prevalence in the General Population Using Healthy Subjects

por Rosengren, Sanna, Souratha, Jennifer, Conway, Dave, Muchmore, Douglas B., Sugarman, Barry J.
Publicado 2018

Dispersive effects and focused biodistribution of recombinant human hyaluronidase PH20: A locally acting and transiently active permeation enhancer

por Kang, David W., Bittner, Beate, Sugarman, Barry J., Zepeda, Monica L., Printz, Marie A.
Publicado 2021

KIAA1199 expression and hyaluronan degradation colocalize in multiple sclerosis lesions

por Marella, Mathieu, Jadin, Laurence, Keller, Gilbert A, Sugarman, Barry J, Frost, Gregory I, Shepard, H Michael
Publicado 2018

A Phase I Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Recombinant Human Hyaluronidase PH20 Administered Intravenously in Healthy Volunteer...

por Printz, Marie A., Dychter, Samuel S., DeNoia, Emanuel P., Harrigan, Rena, Sugarman, Barry J., Zepeda, Monica, Souratha, Jennifer, Kang, David W., Maneval, Daniel C.
Publicado 2020

Clinical Immunogenicity of rHuPH20, a Hyaluronidase Enabling Subcutaneous Drug Administration

por Rosengren, Sanna, Dychter, Samuel S., Printz, Marie A., Huang, Lei, Schiff, Richard I., Schwarz, Hans-Peter, McVey, John K., Drake, Fred H., Maneval, Dan C., Kennard, Don A., Frost, Gregory I., Sugarman, Barry J., Muchmore, Douglas B.
Publicado 2015

PH20 is not expressed in murine CNS and oligodendrocyte precursor cells

por Marella, Mathieu, Ouyang, Joe, Zombeck, Jonathan, Zhao, Chunmei, Huang, Lei, Connor, Robert J., Phan, Kim B., Jorge, Michael C., Printz, Marie A., Paladini, Rudolph D., Gelb, Arnold B., Huang, Zhongdong, Frost, Gregory I., Sugarman, Barry J., Steinman, Lawrence, Wei, Ge, Shepard, H. Michael, Maneval, Daniel C., Lapinskas, Paula J.
Publicado 2017