ERK: A Double-Edged Sword in Cancer. ERK-Dependent Apoptosis as a Potential Therapeutic Strategy for Cancer

por Sugiura, Reiko, Satoh, Ryosuke, Takasaki, Teruaki
Publicado 2021

More than Just an Immunosuppressant: The Emerging Role of FTY720 as a Novel Inducer of ROS and Apoptosis

por Takasaki, Teruaki, Hagihara, Kanako, Satoh, Ryosuke, Sugiura, Reiko
Publicado 2018

Role of RNA-Binding Proteins in MAPK Signal Transduction Pathway

por Sugiura, Reiko, Satoh, Ryosuke, Ishiwata, Shunji, Umeda, Nanae, Kita, Ayako
Publicado 2011

Studies on the Roles of Clathrin-Mediated Membrane Trafficking and Zinc Transporter Cis4 in the Transport of GPI-Anchored Proteins in Fission Yeast

por Jaiseng, Wurentuya, Fang, Yue, Ma, Yan, Sugiura, Reiko, Kuno, Takayoshi
Publicado 2012

Distinct spatiotemporal distribution of Hsp90 under high-heat and mild-heat stress conditions in fission yeast

por Takasaki, Teruaki, Tomimoto, Naofumi, Ikehata, Takumi, Satoh, Ryosuke, Sugiura, Reiko
Publicado 2021

Autophagy-related genes genetically interact with Pmk1 MAPK signaling in fission yeast

por Takasaki, Teruaki, Utsumi, Ryosuke, Shimada, Erika, Tomimoto, Naofumi, Satoh, Ryosuke, Sugiura, Reiko
Publicado 2022

Transient Receptor Potential (TRP) and Cch1-Yam8 Channels Play Key Roles in the Regulation of Cytoplasmic Ca(2+) in Fission Yeast

por Ma, Yan, Sugiura, Reiko, Koike, Atsushi, Ebina, Hidemine, Sio, Susie O., Kuno, Takayoshi
Publicado 2011

Atg1, a key regulator of autophagy, functions to promote MAPK activation and cell death upon calcium overload in fission yeast

por Takasaki, Teruaki, Utsumi, Ryosuke, Shimada, Erika, Bamba, Asuka, Hagihara, Kanako, Satoh, Ryosuke, Sugiura, Reiko
Publicado 2023

ACA-28, an anticancer compound, induces Pap1 nuclear accumulation via ROS-dependent and -independent mechanisms in fission yeast

por Takasaki, Teruaki, Obana, Reo, Fujiwara, Daiki, Tomimoto, Naofumi, Khandakar, Golam Iftakhar, Satoh, Ryosuke, Sugiura, Reiko
Publicado 2023

A genome-wide screen for FTY720-sensitive mutants reveals genes required for ROS homeostasis

por Hagihara, Kanako, Kinoshita, Kanako, Ishida, Kouki, Hojo, Shihomi, Kameoka, Yoshinori, Satoh, Ryosuke, Takasaki, Teruaki, Sugiura, Reiko
Publicado 2017

Essential roles of class E Vps proteins for sorting into multivesicular bodies in Schizosaccharomyces pombe

por Iwaki, Tomoko, Onishi, Masayuki, Ikeuchi, Masaru, Kita, Ayako, Sugiura, Reiko, Giga-Hama, Yuko, Fukui, Yasuhisa, Takegawa, Kaoru
Publicado 2007

ACAGT-007a, an ERK MAPK Signaling Modulator, in Combination with AKT Signaling Inhibition Induces Apoptosis in KRAS Mutant Pancreatic Cancer T3M4 and MIA-Pa-Ca-2 Cells

por Khandakar, Golam Iftakhar, Satoh, Ryosuke, Takasaki, Teruaki, Fujitani, Kana, Tanabe, Genzoh, Sakai, Kazuko, Nishio, Kazuto, Sugiura, Reiko
Publicado 2022

Sip1, a Conserved AP-1 Accessory Protein, Is Important for Golgi/Endosome Trafficking in Fission Yeast

por Yu, Yang, Kita, Ayako, Udo, Masako, Katayama, Yuta, Shintani, Mami, Park, Kwihwa, Hagihara, Kanako, Umeda, Nanae, Sugiura, Reiko
Publicado 2012

Negative feedback regulation of calcineurin-dependent Prz1 transcription factor by the CaMKK-CaMK1 axis in fission yeast

por Cisneros-Barroso, Eugenia, Yance-Chávez, Tula, Kito, Ayako, Sugiura, Reiko, Gómez-Hierro, Alba, Giménez-Zaragoza, David, Aligue, Rosa
Publicado 2014

Role of the Small GTPase Rho3 in Golgi/Endosome Trafficking through Functional Interaction with Adaptin in Fission Yeast

por Kita, Ayako, Li, Cuifang, Yu, Yang, Umeda, Nanae, Doi, Akira, Yasuda, Mitsuko, Ishiwata, Shunji, Taga, Atsushi, Horiuchi, Yoshitaka, Sugiura, Reiko
Publicado 2011

Sip1, an AP-1 Accessory Protein in Fission Yeast, Is Required for Localization of Rho3 GTPase

por Yu, Yang, Li, Cuifang, Kita, Ayako, Katayama, Yuta, Kubouchi, Koji, Udo, Masako, Imanaka, Yukako, Ueda, Shiho, Masuko, Takashi, Sugiura, Reiko
Publicado 2013

Fingolimod (FTY720) Stimulates Ca(2+)/Calcineurin Signaling in Fission Yeast

por Hagihara, Kanako, Kita, Ayako, Mizukura, Aya, Yao, Mariko, Kitai, Yuki, Kunoh, Tatsuki, Masuko, Takashi, Matzno, Sumio, Chiba, Kenji, Sugiura, Reiko
Publicado 2013

Role of the RNA-Binding Protein Nrd1 in Stress Granule Formation and Its Implication in the Stress Response in Fission Yeast

por Satoh, Ryosuke, Tanaka, Akitomo, Kita, Ayako, Morita, Takahiro, Matsumura, Yasuhiro, Umeda, Nanae, Takada, Makoto, Hayashi, Sachiko, Tani, Tokio, Shinmyozu, Kaori, Sugiura, Reiko
Publicado 2012

Oncogenic transformation of NIH/3T3 cells by the overexpression of L-type amino acid transporter 1, a promising anti-cancer target

por Hayashi, Natsumi, Yamasaki, Akitaka, Ueda, Shiho, Okazaki, Shogo, Ohno, Yoshiya, Tanaka, Toshiyuki, Endo, Yuichi, Tomioka, Yoshihisa, Masuko, Kazue, Masuko, Takashi, Sugiura, Reiko
Publicado 2021

The Cell Surface Protein Gene ecm33(+) Is a Target of the Two Transcription Factors Atf1 and Mbx1 and Negatively Regulates Pmk1 MAPK Cell Integrity Signaling in Fission Yeast

por Takada, Hirofumi, Nishida, Aiko, Domae, Mitsuhiro, Kita, Ayako, Yamano, Yuki, Uchida, Atsushi, Ishiwata, Shunji, Fang, Yue, Zhou, Xin, Masuko, Takashi, Kinoshita, Mitsuhiro, Kakehi, Kazuaki, Sugiura, Reiko
Publicado 2010