Nanoparticle anchoring targets immune agonists to tumors enabling anti-cancer immunity without systemic toxicity

por Zhang, Yuan, Li, Na, Suh, Heikyung, Irvine, Darrell J.
Publicado 2018

Microfluidic Control of Cell Pairing and Fusion

por Skelley, Alison M., Kirak, Oktay, Suh, Heikyung, Jaenisch, Rudolf, Voldman, Joel
Publicado 2009

Antigen-Displaying Lipid-Enveloped PLGA Nanoparticles as Delivery Agents for a Plasmodium vivax Malaria Vaccine

por Moon, James J., Suh, Heikyung, Polhemus, Mark E., Ockenhouse, Christian F., Yadava, Anjali, Irvine, Darrell J.
Publicado 2012

Neoadjuvant STING Activation, Extended Half-life IL2, and Checkpoint Blockade Promote Metastasis Clearance via Sustained NK-cell Activation

por Milling, Lauren E., Garafola, Daniel, Agarwal, Yash, Wu, Shengwei, Thomas, Ayush, Donahue, Nathan, Adams, Josetta, Thai, Nikki, Suh, Heikyung, Irvine, Darrell J.
Publicado 2022

Layer‐by‐layer interleukin‐12 nanoparticles drive a safe and effective response in ovarian tumors

por Barberio, Antonio E., Smith, Sean G., Pires, Ivan S., Iyer, Sonia, Reinhardt, Ferenc, Melo, Mariane B., Suh, Heikyung, Weinberg, Robert A., Irvine, Darrell J., Hammond, Paula T.
Publicado 2022

Reprogramming NK cells and macrophages via combined antibody and cytokine therapy primes tumors for elimination by checkpoint blockade

por Wang, Chensu, Cui, Ang, Bukenya, Maurice, Aung, Aereas, Pradhan, Dikshant, Whittaker, Charles A., Agarwal, Yash, Thomas, Ayush, Liang, Simon, Amlashi, Parastoo, Suh, Heikyung, Spranger, Stefani, Hacohen, Nir, Irvine, Darrell J.
Publicado 2021

Interbilayer-Crosslinked Multilamellar Vesicles as Synthetic Vaccines for Potent Humoral and Cellular Immune Responses

por Moon, James J., Suh, Heikyung, Bershteyn, Anna, Stephan, Matthias T., Liu, Haipeng, Huang, Bonnie, Sohail, Mashaal, Luo, Samantha, Um, Soong Ho, Khant, Htet, Goodwin, Jessica T., Ramos, Jenelyn, Chiu, Wah, Irvine, Darrell J.
Publicado 2011

Optimization of an alum-anchored clinical HIV vaccine candidate

por Rodrigues, Kristen A., Cottrell, Christopher A., Steichen, Jon M., Groschel, Bettina, Abraham, Wuhbet, Suh, Heikyung, Agarwal, Yash, Ni, Kaiyuan, Chang, Jason Y. H., Yousefpour, Parisa, Melo, Mariane B., Schief, William R., Irvine, Darrell J.
Publicado 2023

Co‐Anchoring of Engineered Immunogen and Immunostimulatory Cytokines to Alum Promotes Enhanced‐Humoral Immunity

por Chang, Jason Y. H., Agarwal, Yash, Rodrigues, Kristen A., Momin, Noor, Ni, Kaiyuan, Read, Benjamin J., Moyer, Tyson J., Mehta, Naveen K., Silva, Murillo, Suh, Heikyung, Melo, Mariane B., Wittrup, K. Dane, Irvine, Darrell J.
Publicado 2022

Vaccine-boosted CAR T crosstalk with host immunity to reject tumors with antigen heterogeneity

por Ma, Leyuan, Hostetler, Alexander, Morgan, Duncan M., Maiorino, Laura, Sulkaj, Ina, Whittaker, Charles A., Neeser, Alexandra, Pires, Ivan Susin, Yousefpour, Parisa, Gregory, Justin, Qureshi, Kashif, Dye, Jonathan, Abraham, Wuhbet, Suh, Heikyung, Li, Na, Love, J. Christopher, Irvine, Darrell J.
Publicado 2023

Vaccine delivery with microneedle skin patches in nonhuman primates

por DeMuth, Peter C., Li, Adrienne V., Abbink, Peter, Liu, Jinyan, Li, Hualin, Stanley, Kelly A., Smith, Kaitlin M., Lavine, Christy L., Seaman, Michael S., Kramer, Joshua A., Miller, Andrew D., Abraham, Wuhbet, Suh, Heikyung, Elkhader, Jamal, Hammond, Paula T., Barouch, Dan H., Irvine, Darrell J.
Publicado 2013

Intranasal vaccination with lipid-conjugated immunogens promotes antigen transmucosal uptake to drive mucosal and systemic immunity

por Hartwell, Brittany L., Melo, Mariane B., Xiao, Peng, Lemnios, Ashley A., Li, Na, Chang, Jason Y.H., Yu, Jingyou, Gebre, Makda S., Chang, Aiquan, Maiorino, Laura, Carter, Crystal, Moyer, Tyson J., Dalvie, Neil C., Rodriguez-Aponte, Sergio A., Rodrigues, Kristen A., Silva, Murillo, Suh, Heikyung, Adams, Josetta, Fontenot, Jane, Love, J. Christopher, Barouch, Dan H., Villinger, Francois, Ruprecht, Ruth M., Irvine, Darrell J.
Publicado 2022