Physiological Level Production of Antigen-Specific Human Immunoglobulin in Cloned Transchromosomic Cattle

por Sano, Akiko, Matsushita, Hiroaki, Wu, Hua, Jiao, Jin-An, Kasinathan, Poothappillai, Sullivan, Eddie J., Wang, Zhongde, Kuroiwa, Yoshimi
Publicado 2013

Correction: Physiological Level Production of Antigen-Specific Human Immunoglobulin in Cloned Transchromosomic Cattle

por Sano, Akiko, Matsushita, Hiroaki, Wu, Hua, Jiao, Jin-An, Kasinathan, Poothappillai, Sullivan, Eddie J., Wang, Zhongde, Kuroiwa, Yoshimi
Publicado 2014

Triple Immunoglobulin Gene Knockout Transchromosomic Cattle: Bovine Lambda Cluster Deletion and Its Effect on Fully Human Polyclonal Antibody Production

por Matsushita, Hiroaki, Sano, Akiko, Wu, Hua, Jiao, Jin-an, Kasinathan, Poothappillai, Sullivan, Eddie J., Wang, Zhongde, Kuroiwa, Yoshimi
Publicado 2014

Species-Specific Chromosome Engineering Greatly Improves Fully Human Polyclonal Antibody Production Profile in Cattle

por Matsushita, Hiroaki, Sano, Akiko, Wu, Hua, Wang, Zhongde, Jiao, Jin-an, Kasinathan, Poothappillai, Sullivan, Eddie J., Kuroiwa, Yoshimi
Publicado 2015

Human immunoglobulin from transchromosomic bovines hyperimmunized with SARS-CoV-2 spike antigen efficiently neutralizes viral variants

por Liu, Zhuoming, Wu, Hua, Egland, Kristi A., Gilliland, Theron C., Dunn, Matthew D., Luke, Thomas C., Sullivan, Eddie J., Klimstra, William B., Bausch, Christoph L., Whelan, Sean P. J.
Publicado 2021

Generation of H7N9-specific human polyclonal antibodies from a transchromosomic goat (caprine) system

por Wu, Hua, Fan, Zhiqiang, Brandsrud, Michelle, Meng, Qinggang, Bobbitt, Molly, Regouski, Misha, Stott, Rusty, Sweat, Alexis, Crabtree, Jackelyn, Hogan, Robert J., Tripp, Ralph A., Wang, Zhongde, Polejaeva, Irina A., Sullivan, Eddie J.
Publicado 2019

Human Polyclonal Antibodies Produced through DNA Vaccination of Transchromosomal Cattle Provide Mice with Post-Exposure Protection against Lethal Zaire and Sudan Ebolaviruses

por Bounds, Callie E., Kwilas, Steven A., Kuehne, Ana I., Brannan, Jennifer M., Bakken, Russell R., Dye, John M., Hooper, Jay W., Dupuy, Lesley C., Ellefsen, Barry, Hannaman, Drew, Wu, Hua, Jiao, Jin-an, Sullivan, Eddie J., Schmaljohn, Connie S.
Publicado 2015

Polyclonal Antibodies Derived from Transchromosomic Bovines Vaccinated with the Recombinant F1-V Vaccine Increase Bacterial Opsonization In Vitro and Protect Mice from Pneumonic Pl...

por Biryukov, Sergei S., Wu, Hua, Dankmeyer, Jennifer L., Rill, Nathaniel O., Klimko, Christopher P., Egland, Kristi A., Shoe, Jennifer L., Hunter, Melissa, Fetterer, David P., Qiu, Ju, Davies, Michael L., Bausch, Christoph L., Sullivan, Eddie J., Luke, Thomas, Cote, Christopher K.
Publicado 2023

Production of Potent Fully Human Polyclonal Antibodies against Ebola Zaire Virus in Transchromosomal Cattle

por Dye, John M., Wu, Hua, Hooper, Jay W., Khurana, Surender, Kuehne, Ana I., Coyle, Elizabeth M., Ortiz, Ramon A., Fuentes, Sandra, Herbert, Andrew S., Golding, Hana, Bakken, Russell A., Brannan, Jennifer M., Kwilas, Steve A., Sullivan, Eddie J., Luke, Thomas C., Smith, Gale, Glenn, Gregory, Li, Wenfang, Ye, Ling, Yang, Chinglai, Compans, Richard W., Tripp, Ralph A., Jiao, Jin-an
Publicado 2016