The role of SQSTM1 (p62) in mitochondrial function and clearance in human cortical neurons

por Poon, Anna, Saini, Harpreet, Sethi, Siddharth, O'Sullivan, Gregory A., Plun-Favreau, Hélène, Wray, Selina, Dawson, Lee A., McCarthy, James M.
Publicado 2021

Environmental toxins trigger PD-like progression via increased alpha-synuclein release from enteric neurons in mice

por Pan-Montojo, Francisco, Schwarz, Mathias, Winkler, Clemens, Arnhold, Mike, O'Sullivan, Gregory A., Pal, Arun, Said, Jonas, Marsico, Giovanni, Verbavatz, Jean-Marc, Rodrigo-Angulo, Margarita, Gille, Gabriele, Funk, Richard H. W., Reichmann, Heinz
Publicado 2012

AKT signalling selectively regulates PINK1 mitophagy in SHSY5Y cells and human iPSC-derived neurons

por Soutar, Marc P. M., Kempthorne, Liam, Miyakawa, Shuichi, Annuario, Emily, Melandri, Daniela, Harley, Jasmine, O’Sullivan, Gregory A., Wray, Selina, Hancock, David C., Cookson, Mark R., Downward, Julian, Carlton, Mark, Plun-Favreau, Hélène
Publicado 2018

A dual druggable genome-wide siRNA and compound library screening approach identifies modulators of parkin recruitment to mitochondria

por Scott, Helen L., Buckner, Nicola, Fernandez-Albert, Francesc, Pedone, Elisa, Postiglione, Lorena, Shi, Gongyu, Allen, Nicholas, Wong, Liang-Fong, Magini, Lorenzo, Marucci, Lucia, O'Sullivan, Gregory A., Cole, Sarah, Powell, Justin, Maycox, Peter, Uney, James B.
Publicado 2020