Tissue functions mediated by β(3)-adrenoceptors—findings and challenges

por Michel, Martin C., Ochodnicky, Peter, Summers, Roger J.
Publicado 2010

Evolution of β-blockers: from anti-anginal drugs to ligand-directed signalling

por Baker, Jillian G., Hill, Stephen J., Summers, Roger J.
Publicado 2011

Editorial: Recent Advances in G Protein-Coupled Receptor Signalling: Impact of Intracellular Location, Environment and Biased Agonism

por Halls, Michelle L., Davenport, Anthony P., Summers, Roger J.
Publicado 2021

Comparative genotypic and phenotypic analysis of human peripheral blood monocytes and surrogate monocyte-like cell lines commonly used in metabolic disease research

por Riddy, Darren M., Goy, Emily, Delerive, Philippe, Summers, Roger J., Sexton, Patrick M., Langmead, Christopher J.
Publicado 2018

Rosiglitazone and a β(3)-Adrenoceptor Agonist Are Both Required for Functional Browning of White Adipocytes in Culture

por Merlin, Jon, Sato, Masaaki, Chia, Ling Yeong, Fahey, Richard, Pakzad, Mohsen, Nowell, Cameron J., Summers, Roger J., Bengtsson, Tore, Evans, Bronwyn A., Hutchinson, Dana S.
Publicado 2018

Pharmacological Insights Into Safety and Efficacy Determinants for the Development of Adenosine Receptor Biased Agonists in the Treatment of Heart Failure

por Rueda, Patricia, Merlin, Jon, Chimenti, Stefano, Feletou, Michel, Paysant, Jerome, White, Paul J., Christopoulos, Arthur, Sexton, Patrick M., Summers, Roger J., Charman, William N., May, Lauren T., Langmead, Christopher J.
Publicado 2021

ML290 is a biased allosteric agonist at the relaxin receptor RXFP1

por Kocan, Martina, Sarwar, Mohsin, Ang, Sheng Y., Xiao, Jingbo, Marugan, Juan J., Hossain, Mohammed A., Wang, Chao, Hutchinson, Dana S., Samuel, Chrishan S., Agoulnik, Alexander I., Bathgate, Ross A. D., Summers, Roger J.
Publicado 2017

Orthosteric Binding of ρ-Da1a, a Natural Peptide of Snake Venom Interacting Selectively with the α(1A)-Adrenoceptor

por Maïga, Arhamatoulaye, Merlin, Jon, Marcon, Elodie, Rouget, Céline, Larregola, Maud, Gilquin, Bernard, Fruchart-Gaillard, Carole, Lajeunesse, Evelyne, Marchetti, Charles, Lorphelin, Alain, Bellanger, Laurent, Summers, Roger J., Hutchinson, Dana S., Evans, Bronwyn A., Servent, Denis, Gilles, Nicolas
Publicado 2013

The metabolic effects of mirabegron are mediated primarily by β(3)‐adrenoceptors

por Dehvari, Nodi, Sato, Masaaki, Bokhari, Muhammad Hamza, Kalinovich, Anastasia, Ham, Seungmin, Gao, Jie, Nguyen, Huong T. M., Whiting, Lynda, Mukaida, Saori, Merlin, Jon, Chia, Ling Yeong, Wootten, Denise, Summers, Roger J., Evans, Bronwyn A., Bengtsson, Tore, Hutchinson, Dana S.
Publicado 2020

A single-chain derivative of the relaxin hormone is a functionally selective agonist of the G protein-coupled receptor, RXFP1

por Hossain, Mohammed Akhter, Kocan, Martina, Yao, Song T., Royce, Simon G., Nair, Vinojini B., Siwek, Christopher, Patil, Nitin A., Harrison, Ian P., Rosengren, K. Johan, Selemidis, Stavros, Summers, Roger J., Wade, John D., Bathgate, Ross A. D., Samuel, Chrishan S.
Publicado 2016

Murine GPRC6A Mediates Cellular Responses to L-Amino Acids, but Not Osteocalcin Variants

por Rueda, Patricia, Harley, Elizabeth, Lu, Yao, Stewart, Gregory D., Fabb, Stewart, Diepenhorst, Natalie, Cremers, Béatrice, Rouillon, Marie-Hélène, Wehrle, Isabelle, Geant, Anne, Lamarche, Gwladys, Leach, Katie, Charman, William N., Christopoulos, Arthur, Summers, Roger J., Sexton, Patrick M., Langmead, Christopher J.
Publicado 2016

Deletion of GPR21 improves glucose homeostasis and inhibits the CCL2-CCR2 axis by divergent mechanisms

por Riddy, Darren M, Kammoun, Helene L, Murphy, Andrew J, Bosnyak-Gladovic, Sanja, De la Fuente Gonzalez, Rocio, Merlin, Jon, Ziemann, Mark, Fabb, Stewart, Pierce, Tracie L, Diepenhorst, Natalie, Rueda, Patricia, El-Osta, Assam, Gautier, Jean-Francois, Venteclef, Nicolas, Charman, William N, Christopoulos, Arthur, Sexton, Patrick M, Summers, Roger J, Febbraio, Mark A, Delerive, Philippe, Langmead, Christopher J
Publicado 2021