Discovery and Characterization of ZL-2201, a Potent, Highly Selective, and Orally Bioavailable Small-molecule DNA-PK Inhibitor

por Lal, Shruti, Bhola, Neil E., Sun, Bee-Chun, Chen, Yuping, Huang, Tom, Morton, Vivian, Chen, Kevin X., Xia, Shanghua, Zhang, Haoyu, Parikh, Nehal S., Ye, Qiuping, Veiby, O. Petter, Bellovin, David I., Ji, Yuhua
Publicado 2023

ZL-1211 Exhibits Robust Antitumor Activity by Enhancing ADCC and Activating NK Cell–mediated Inflammation in CLDN18.2-High and -Low Expressing Gastric Cancer Models

por Konno, Hiroyasu, Lin, Tracey, Wu, Renyi, Dai, Xinchuan, Li, Shou, Wang, Grace, Chen, Min, Li, Wenying, Wang, Lina, Sun, Bee-Chun, Luo, Zhen, Huang, Tom, Chen, Yuping, Zhang, John, Ye, Qiuping, Bellovin, David, Wan, Bing, Kang, Lishan, Szeto, Christopher, Hsu, Karl, Kabbarah, Omar
Publicado 2022