Dissection of the catalytic and regulatory structure-function relationships of Csk protein tyrosine kinase

por Sun, Gongqin, Ayrapetov, Marina K.
Publicado 2023

Challenges and Opportunities in Developing Targeted Therapies for Triple Negative Breast Cancer

por Chapdelaine, Abygail G., Sun, Gongqin
Publicado 2023

Characterization of the interactions between the active site of a protein tyrosine kinase and a divalent metal activator

por Lin, Xiaofeng, Ayrapetov, Marina K, Sun, Gongqin
Publicado 2005

Drug Sensitivity Screening and Targeted Pathway Analysis Reveal a Multi-Driver Proliferative Mechanism and Suggest a Strategy of Combination Targeted Therapy for Colorectal Cancer...

por Shen, Jinyan, Li, Li, Yang, Tao, Cheng, Niuliang, Sun, Gongqin
Publicado 2019

Biphasic Mathematical Model of Cell–Drug Interaction That Separates Target-Specific and Off-Target Inhibition and Suggests Potent Targeted Drug Combinations for Multi-Driver Colore...

por Shen, Jinyan, Li, Li, Yang, Tao, Cohen, Paul S., Sun, Gongqin
Publicado 2020

Application of a Biphasic Mathematical Model of Cancer Cell Drug Response for Formulating Potent and Synergistic Targeted Drug Combinations to Triple Negative Breast Cancer Cells

por Shen, Jinyan, Li, Li, Howlett, Niall G., Cohen, Paul S., Sun, Gongqin
Publicado 2020

Identification of Lethal Inhibitors and Inhibitor Combinations for Mono-Driver versus Multi-Driver Triple-Negative Breast Cancer Cells

por Ku, Geng Chia, Chapdelaine, Abygail G., Ayrapetov, Marina K., Sun, Gongqin
Publicado 2022

Ponatinib Inhibits Proliferation and Induces Apoptosis of Liver Cancer Cells, but Its Efficacy Is Compromised by Its Activation on PDK1/Akt/mTOR Signaling

por Liu, Chang, Mu, Xiuli, Wang, Xuan, Zhang, Chan, Zhang, Lina, Yu, Baofeng, Sun, Gongqin
Publicado 2019

Uropathogenic Escherichia coli Metabolite-Dependent Quiescence and Persistence May Explain Antibiotic Tolerance during Urinary Tract Infection

por Leatham-Jensen, Mary P., Mokszycki, Matthew E., Rowley, David C., Deering, Robert, Camberg, Jodi L., Sokurenko, Evgeni V., Tchesnokova, Veronika L., Frimodt-Møller, Jakob, Krogfelt, Karen A., Leth Nielsen, Karen, Frimodt-Møller, Niels, Sun, Gongqin, Cohen, Paul S.
Publicado 2016