The molecular basis of the steep force–calcium relation in heart muscle

por Sun, Yin-Biao, Irving, Malcolm
Publicado 2010

Novel myosin-based therapies for congenital cardiac and skeletal myopathies

por Ochala, Julien, Sun, Yin-Biao
Publicado 2016

Orientation of the N- and C-Terminal Lobes of the Myosin Regulatory Light Chain in Cardiac Muscle

por Kampourakis, Thomas, Sun, Yin-Biao, Irving, Malcolm
Publicado 2015

Omecamtiv mercabil and blebbistatin modulate cardiac contractility by perturbing the regulatory state of the myosin filament

por Kampourakis, Thomas, Zhang, Xuemeng, Sun, Yin‐Biao, Irving, Malcolm
Publicado 2017

Regulatory domain of troponin moves dynamically during activation of cardiac muscle

por Sevrieva, Ivanka, Knowles, Andrea C., Kampourakis, Thomas, Sun, Yin-Biao
Publicado 2014

Structural and functional effects of myosin-binding protein-C phosphorylation in heart muscle are not mimicked by serine-to-aspartate substitutions

por Kampourakis, Thomas, Ponnam, Saraswathi, Sun, Yin-Biao, Sevrieva, Ivanka, Irving, Malcolm
Publicado 2018

Site-specific phosphorylation of myosin binding protein-C coordinates thin and thick filament activation in cardiac muscle

por Ponnam, Saraswathi, Sevrieva, Ivanka, Sun, Yin-Biao, Irving, Malcolm, Kampourakis, Thomas
Publicado 2019

Distinct contributions of the thin and thick filaments to length-dependent activation in heart muscle

por Zhang, Xuemeng, Kampourakis, Thomas, Yan, Ziqian, Sevrieva, Ivanka, Irving, Malcolm, Sun, Yin-Biao
Publicado 2017

Phosphorylation-dependent interactions of myosin-binding protein C and troponin coordinate the myofilament response to protein kinase A

por Sevrieva, Ivanka R., Ponnam, Saraswathi, Yan, Ziqian, Irving, Malcolm, Kampourakis, Thomas, Sun, Yin-Biao
Publicado 2022

Probing the mechanism of cardiovascular drugs using a covalent levosimendan analog

por Pineda-Sanabria, Sandra E., Robertson, Ian M., Sun, Yin-Biao, Irving, Malcolm, Sykes, Brian D.
Publicado 2016

The structural and functional effects of the familial hypertrophic cardiomyopathy-linked cardiac troponin C mutation, L29Q

por Robertson, Ian M., Sevrieva, Ivanka, Li, Monica X., Irving, Malcolm, Sun, Yin-Biao, Sykes, Brian D.
Publicado 2015

Cardiac myosin regulatory light chain kinase modulates cardiac contractility by phosphorylating both myosin regulatory light chain and troponin I

por Sevrieva, Ivanka R., Brandmeier, Birgit, Ponnam, Saraswathi, Gautel, Mathias, Irving, Malcolm, Campbell, Kenneth S., Sun, Yin-Biao, Kampourakis, Thomas
Publicado 2020

Uncoordinated Transcription and Compromised Muscle Function in the Lmna-Null Mouse Model of Emery-Dreifuss Muscular Dystrophy

por Gnocchi, Viola F., Scharner, Juergen, Huang, Zhe, Brady, Ken, Lee, Jaclyn S., White, Robert B., Morgan, Jennifer E., Sun, Yin-Biao, Ellis, Juliet A., Zammit, Peter S.
Publicado 2011

15-deoxy-Δ(12,14)-Prostaglandin J(2) inhibits human soluble epoxide hydrolase by a dual orthosteric and allosteric mechanism

por Abis, Giancarlo, Charles, Rebecca L., Kopec, Jolanta, Yue, Wyatt W., Atkinson, R. Andrew, Bui, Tam T. T., Lynham, Steven, Popova, Simona, Sun, Yin-Biao, Fraternali, Franca, Eaton, Philip, Conte, Maria R.
Publicado 2019