Investigation of the Mechanism of Clearance of AMG 386, a Selective Angiopoietin-1/2 Neutralizing Peptibody, in Splenectomized, Nephrectomized, and FcRn Knockout Rodent Models

por Wu, Benjamin, Johnson, Jessica, Soto, Marcus, Ponce, Manuel, Calamba, Dominador, Sun, Yu-Nien
Publicado 2011

Population‐based cellular kinetic characterization of ciltacabtagene autoleucel in subjects with relapsed or refractory multiple myeloma

por Wu, Liviawati S., Su, Yaming, Li, Claire, Zhou, Wangda, Jackson, Carolyn C., Sun, Yu‐Nien, Zhou, Honghui
Publicado 2022

Phase II study of motesanib in Japanese patients with advanced gastrointestinal stromal tumors with prior exposure to imatinib mesylate

por Sawaki, Akira, Yamada, Yasuhide, Komatsu, Yoshito, Kanda, Tatsuo, Doi, Toshihiko, Koseki, Masato, Baba, Hideo, Sun, Yu-Nien, Murakami, Koji, Nishida, Toshirou
Publicado 2009

Safety and Pharmacokinetics of Motesanib in Combination with Panitumumab and Gemcitabine-Cisplatin in Patients with Advanced Cancer

por Burris, Howard, Stephenson, Joe, Otterson, Gregory A., Stein, Mark, McGreivy, Jesse, Sun, Yu-Nien, Ingram, Megan, Ye, Yining, Schwartzberg, Lee S.
Publicado 2011

Safety and pharmacokinetics of motesanib in combination with gemcitabine and erlotinib for the treatment of solid tumors: a phase 1b study

por Kotasek, Dusan, Tebbutt, Niall, Desai, Jayesh, Welch, Stephen, Siu, Lillian L, McCoy, Sheryl, Sun, Yu-Nien, Johnson, Jessica, Adewoye, Adeboye H, Price, Timothy
Publicado 2011

Exposure–response relationship of AMG 386 in combination with weekly paclitaxel in recurrent ovarian cancer and its implication for dose selection

por Lu, Jian-Feng, Rasmussen, Erik, Karlan, Beth Y., Vergote, Ignace B., Navale, Lynn, Kuchimanchi, Mita, Melara, Rebeca, Stepan, Daniel E., Weinreich, David M., Sun, Yu-Nien
Publicado 2012

A randomized, double-blind study of AMG 108 (a fully human monoclonal antibody to IL-1R1) in patients with osteoarthritis of the knee

por Cohen, Stanley B, Proudman, Susanna, Kivitz, Alan J, Burch, Francis X, Donohue, John P, Burstein, Deborah, Sun, Yu-Nien, Banfield, Christopher, Vincent, Michael S, Ni, Liyun, Zack, Debra J
Publicado 2011

Split First Dose Administration of Intravenous Daratumumab for the Treatment of Multiple Myeloma (MM): Clinical and Population Pharmacokinetic Analyses

por Xu, Xu Steven, Moreau, Philippe, Usmani, Saad Z., Lonial, Sagar, Jakubowiak, Andrzej, Oriol, Albert, Krishnan, Amrita, Bladé, Joan, Luo, Man, Sun, Yu-Nien, Zhou, Honghui, Nnane, Ivo, Deraedt, William, Qi, Ming, Ukropec, Jon, Clemens, Pamela L.
Publicado 2020

Exposure‐Response and Population Pharmacokinetic Analyses of a Novel Subcutaneous Formulation of Daratumumab Administered to Multiple Myeloma Patients

por Luo, Man (Melody), Usmani, Saad Z., Mateos, Maria‐Victoria, Nahi, Hareth, Chari, Ajai, San‐Miguel, Jesus, Touzeau, Cyrille, Suzuki, Kenshi, Kaiser, Martin, Carson, Robin, Heuck, Christoph, Qi, Ming, Zhou, Honghui, Sun, Yu‐Nien, Parasrampuria, Dolly A.
Publicado 2020

Efficacy and safety of motesanib, an oral inhibitor of VEGF, PDGF, and Kit receptors, in patients with imatinib-resistant gastrointestinal stromal tumors

por Benjamin, Robert S., Schöffski, Patrick, Hartmann, Jörg Thomas, Van Oosterom, Allan, Bui, Binh Nguyen, Duyster, Justus, Schuetze, Scott, Blay, Jean-Yves, Reichardt, Peter, Rosen, Lee S., Skubitz, Keith, McCoy, Sheryl, Sun, Yu-Nien, Stepan, Daniel E., Baker, Laurence
Publicado 2010

Pharmacokinetics and Exposure–Response Analyses of Daratumumab in Combination Therapy Regimens for Patients with Multiple Myeloma

por Xu, Xu Steven, Dimopoulos, Meletios A., Sonneveld, Pieter, Ho, P. Joy, Belch, Andrew, Leiba, Merav, Capra, Marcelo, Gomez, David, Medvedova, Eva, Iida, Shinsuke, Min, Chang-Ki, Schecter, Jordan, Jansson, Richard, Zhang, Liping, Sun, Yu-Nien, Clemens, Pamela L.
Publicado 2018

Translational Modeling Predicts Efficacious Therapeutic Dosing Range of Teclistamab for Multiple Myeloma

por Girgis, Suzette, Lin, Shun Xin Wang, Pillarisetti, Kodandaram, Banerjee, Arnob, Stephenson, Tara, Ma, Xuewen, Shetty, Shoba, Yang, Tong-Yuan, Hilder, Brandi W., Jiao, Qun, Hanna, Brett, Adams, Homer C, Sun, Yu-Nien, Sharma, Amarnath, Smit, Jennifer, Infante, Jeffrey R., Goldberg, Jenna D., Elsayed, Yusri
Publicado 2022

Correction: Translational Modeling Predicts Efficacious Therapeutic Dosing Range of Teclistamab for Multiple Myeloma

por Girgis, Suzette, Lin, Shun Xin Wang, Pillarisetti, Kodandaram, Banerjee, Arnob, Stephenson, Tara, Ma, Xuewen, Shetty, Shoba, Yang, Tong-Yuan, Hilder, Brandi W., Jiao, Qun, Hanna, Brett, Adams, Homer C., Sun, Yu-Nien, Sharma, Amarnath, Smit, Jennifer, Infante, Jeffrey R., Goldberg, Jenna D., Elsayed, Yusri
Publicado 2022