Mitochondrial roles in disease: a box full of surprises

por Suomalainen, Anu
Publicado 2015

Quantitative solid-phase assay to measure deoxynucleoside triphosphate pools

por Landoni, Juan Cruz, Wang, Liya, Suomalainen, Anu
Publicado 2018

Clustering of Alpers disease mutations and catalytic defects in biochemical variants reveal new features of molecular mechanism of the human mitochondrial replicase, Pol γ

por Euro, Liliya, Farnum, Gregory A., Palin, Eino, Suomalainen, Anu, Kaguni, Laurie S.
Publicado 2011

Alternative oxidase causes cell type- and tissue-specific responses in mutator mice

por Ikonen, Lilli, Pirnes-Karhu, Sini, Pradhan, Swagat, Jacobs, Howard T, Szibor, Marten, Suomalainen, Anu
Publicado 2023

Mitochondrial spongiotic brain disease: astrocytic stress and harmful rapamycin and ketosis effect

por Ignatenko, Olesia, Nikkanen, Joni, Kononov, Alexander, Zamboni, Nicola, Ince-Dunn, Gulayse, Suomalainen, Anu
Publicado 2020

Twinkle mutations associated with autosomal dominant progressive external ophthalmoplegia lead to impaired helicase function and in vivo mtDNA replication stalling

por Goffart, Steffi, Cooper, Helen M., Tyynismaa, Henna, Wanrooij, Sjoerd, Suomalainen, Anu, Spelbrink, Johannes N.
Publicado 2009

Lowered oxidative capacity in spinal muscular atrophy, Jokela type; comparison with mitochondrial muscle disease

por Ratia, Nadja, Palu, Edouard, Lantto, Hanna, Ylikallio, Emil, Luukkonen, Ritva, Suomalainen, Anu, Auranen, Mari, Piirilä, Päivi
Publicado 2023

Disruption of the mouse Shmt2 gene confers embryonic anaemia via foetal liver-specific metabolomic disorders

por Tani, Haruna, Mito, Takayuki, Velagapudi, Vidya, Ishikawa, Kaori, Umehara, Moe, Nakada, Kazuto, Suomalainen, Anu, Hayashi, Jun-Ichi
Publicado 2019

IMPDH2: a new gene associated with dominant juvenile-onset dystonia-tremor disorder

por Kuukasjärvi, Anna, Landoni, Juan C., Kaukonen, Jyrki, Juhakoski, Mika, Auranen, Mari, Torkkeli, Tommi, Velagapudi, Vidya, Suomalainen, Anu
Publicado 2021

Mitochondrial dysfunction triggers actin polymerization necessary for rapid glycolytic activation

por Chakrabarti, Rajarshi, Fung, Tak Shun, Kang, Taewook, Elonkirjo, Pieti W., Suomalainen, Anu, Usherwood, Edward J., Higgs, Henry N.
Publicado 2022

Developmental and Pathological Changes in the Human Cardiac Muscle Mitochondrial DNA Organization, Replication and Copy Number

por Pohjoismäki, Jaakko L. O., Goffart, Steffi, Taylor, Robert W., Turnbull, Douglas M., Suomalainen, Anu, Jacobs, Howard T., Karhunen, Pekka J.
Publicado 2010

Ribonucleotide reductase is not limiting for mitochondrial DNA copy number in mice

por Ylikallio, Emil, Page, Jennifer L., Xu, Xia, Lampinen, Milla, Bepler, Gerold, Ide, Tomomi, Tyynismaa, Henna, Weiss, Robert S., Suomalainen, Anu
Publicado 2010

mtDNA Mutagenesis Disrupts Pluripotent Stem Cell Function by Altering Redox Signaling

por Hämäläinen, Riikka H., Ahlqvist, Kati J., Ellonen, Pekka, Lepistö, Maija, Logan, Angela, Otonkoski, Timo, Murphy, Michael P., Suomalainen, Anu
Publicado 2015

A complex genomic locus drives mtDNA replicase POLG expression to its disease‐related nervous system regions

por Nikkanen, Joni, Landoni, Juan Cruz, Balboa, Diego, Haugas, Maarja, Partanen, Juha, Paetau, Anders, Isohanni, Pirjo, Brilhante, Virginia, Suomalainen, Anu
Publicado 2017

Using urine to diagnose large‐scale mtDNA deletions in adult patients

por Varhaug, Kristin N., Nido, Gonzalo S., de Coo, Irenaeus, Isohanni, Pirjo, Suomalainen, Anu, Tzoulis, Charalampos, Knappskog, Per, Bindoff, Laurence A.
Publicado 2020

Mosaic dysfunction of mitophagy in mitochondrial muscle disease

por Mito, Takayuki, Vincent, Amy E., Faitg, Julie, Taylor, Robert W., Khan, Nahid A., McWilliams, Thomas G., Suomalainen, Anu
Publicado 2022

Mitochondrial dysfunction compromises ciliary homeostasis in astrocytes

por Ignatenko, Olesia, Malinen, Satu, Rybas, Sofiia, Vihinen, Helena, Nikkanen, Joni, Kononov, Aleksander, Jokitalo, Eija S., Ince-Dunn, Gulayse, Suomalainen, Anu
Publicado 2022

Phenotypic effects of dietary stress in combination with a respiratory chain bypass in mice

por Dhandapani, Praveen K., Lyyski, Annina M., Paulin, Lars, Khan, Nahid A., Suomalainen, Anu, Auvinen, Petri, Dufour, Eric, Szibor, Marten, Jacobs, Howard T.
Publicado 2019

Genetic background of ataxia in children younger than 5 years in Finland

por Ignatius, Erika, Isohanni, Pirjo, Pohjanpelto, Max, Lahermo, Päivi, Ojanen, Simo, Brilhante, Virginia, Palin, Eino, Suomalainen, Anu, Lönnqvist, Tuula, Carroll, Christopher J.
Publicado 2020

Varied Responses to a High m.3243A>G Mutation Load and Respiratory Chain Dysfunction in Patient-Derived Cardiomyocytes

por Ryytty, Sanna, Modi, Shalem R., Naumenko, Nikolay, Shakirzyanova, Anastasia, Rahman, Muhammad Obaidur, Vaara, Miia, Suomalainen, Anu, Tavi, Pasi, Hämäläinen, Riikka H.
Publicado 2022