Rapid optimisation of fragments and hits to lead compounds from screening of crude reaction mixtures

por Baker, Lisa M., Aimon, Anthony, Murray, James B., Surgenor, Allan E., Matassova, Natalia, Roughley, Stephen D., Collins, Patrick M., Krojer, Tobias, von Delft, Frank, Hubbard, Roderick E.
Publicado 2020

The Effect of Core Replacement on S64315, a Selective MCL-1 Inhibitor, and Its Analogues

por Sipos, Szabolcs, Bálint, Balázs, Szabó, Zoltán B., Ondi, Levente, Csékei, Márton, Szlávik, Zoltán, Proszenyák, Ágnes, Murray, James B., Davidson, James, Chen, Ijen, Dokurno, Pawel, Surgenor, Allan E., Pedder, Christopher, Hubbard, Roderick E., Maragno, Ana-Leticia, Chanrion, Maia, Colland, Frederic, Geneste, Olivier, Kotschy, András
Publicado 2021