CRISPR Screens in Synthetic Lethality and Combinatorial Therapies for Cancer

por Castells-Roca, Laia, Tejero, Eudald, Rodríguez-Santiago, Benjamín, Surrallés, Jordi
Publicado 2021

Functional Comparison of XPF Missense Mutations Associated to Multiple DNA Repair Disorders

por Marín, Maria, Ramírez, María José, Aza Carmona, Miriam, Jia, Nan, Ogi, Tomoo, Bogliolo, Massimo, Surrallés, Jordi
Publicado 2019

Fanconi anemia protein FANCD2 inhibits TRF1 polyADP-ribosylation through tankyrase1-dependent manner

por Lyakhovich, Alex, Ramirez, Maria Jose, Castellanos, Andres, Castella, Maria, Simons, Amanda M, Parvin, Jeffrey D, Surralles, Jordi
Publicado 2011

Mosaicism in Fanconi anemia: concise review and evaluation of published cases with focus on clinical course of blood count normalization

por Nicoletti, Eileen, Rao, Gayatri, Bueren, Juan A., Río, Paula, Navarro, Susana, Surrallés, Jordi, Choi, Grace, Schwartz, Jonathan D.
Publicado 2020

High content drug screening for Fanconi anemia therapeutics

por Montanuy, Helena, Camps-Fajol, Cristina, Carreras-Puigvert, Jordi, Häggblad, Maria, Lundgren, Bo, Aza-Carmona, Miriam, Helleday, Thomas, Minguillón, Jordi, Surrallés, Jordi
Publicado 2020

Dyslipidemia and Chronic Inflammation Markers Are Correlated with Telomere Length Shortening in Cushing’s Syndrome

por Aulinas, Anna, Ramírez, María-José, Barahona, María-José, Valassi, Elena, Resmini, Eugenia, Mato, Eugènia, Santos, Alicia, Crespo, Iris, Bell, Olga, Surrallés, Jordi, Webb, Susan M.
Publicado 2015

Dysfunctional telomeres in primary cells from Fanconi anemia FANCD2 patients

por Joksic, Ivana, Vujic, Dragana, Guc-Scekic, Marija, Leskovac, Andreja, Petrovic, Sandra, Ojani, Maryam, Trujillo, Juan P, Surralles, Jordi, Zivkovic, Maja, Stankovic, Aleksandra, Slijepcevic, Predrag, Joksic, Gordana
Publicado 2012

Biallelic germline BRCA1 mutations in a patient with early onset breast cancer, mild Fanconi anemia‐like phenotype, and no chromosome fragility

por Keupp, Katharina, Hampp, Stephanie, Hübbel, Annette, Maringa, Monika, Kostezka, Sarah, Rhiem, Kerstin, Waha, Anke, Wappenschmidt, Barbara, Pujol, Roser, Surrallés, Jordi, Schmutzler, Rita K., Wiesmüller, Lisa, Hahnen, Eric
Publicado 2019

Novel Somatic Genetic Variants as Predictors of Resistance to EGFR-Targeted Therapies in Metastatic Colorectal Cancer Patients

por Riera, Pau, Rodríguez-Santiago, Benjamín, Lasa, Adriana, Gonzalez-Quereda, Lidia, Martín, Berta, Salazar, Juliana, Sebio, Ana, Virgili, Anna C., Minguillón, Jordi, Camps, Cristina, Surrallés, Jordi, Páez, David
Publicado 2020

Limited detection of human polyomaviruses in Fanconi anemia related squamous cell carcinoma

por Toptan, Tuna, Brusadelli, Marion G., Turpin, Brian, Witte, David P., Surrallés, Jordi, Velleuer, Eunike, Schramm, Martin, Dietrich, Ralf, Brakenhoff, Ruud H., Moore, Patrick S., Chang, Yuan, Wells, Susanne I.
Publicado 2018

A self-repair history: compensatory effect of a de novo variant on the FANCA c.2778+83C>G splicing mutation

por Persico, Ilaria, Fontana, Giorgia, Faleschini, Michela, Zanchetta, Melania Eva, Ammeti, Daniele, Cappelli, Enrico, Corsolini, Fabio, Mosa, Clara, Guarina, Angela, Bogliolo, Massimo, Surrallés, Jordi, Dufour, Carlo, Farruggia, Piero, Savoia, Anna, Bottega, Roberta
Publicado 2023

Epigenetic Alterations in Fanconi Anaemia: Role in Pathophysiology and Therapeutic Potential

por Belo, Hélio, Silva, Gabriela, Cardoso, Bruno A., Porto, Beatriz, Minguillon, Jordi, Barbot, José, Coutinho, Jorge, Casado, Jose A., Benedito, Manuela, Saturnino, Hema, Costa, Emília, Bueren, Juan A., Surralles, Jordi, Almeida, Antonio
Publicado 2015

TALEN mediated gene editing in a mouse model of Fanconi anemia

por Pino-Barrio, Maria José, Giménez, Yari, Villanueva, Mariela, Hildenbeutel, Marcus, Sánchez-Dominguez, Rebeca, Rodríguez-Perales, Sandra, Pujol, Roser, Surrallés, Jordi, Río, Paula, Cathomen, Toni, Mussolino, Claudio, Bueren, Juan Antonio, Navarro, Susana
Publicado 2020

Generating New FANCA-Deficient HNSCC Cell Lines by Genomic Editing Recapitulates the Cellular Phenotypes of Fanconi Anemia

por Errazquin, Ricardo, Sieiro, Esther, Moreno, Pilar, Ramirez, María José, Lorz, Corina, Peral, Jorge, Ortiz, Jessica, Casado, José Antonio, Roman-Rodriguez, Francisco J., Hanenberg, Helmut, Río, Paula, Surralles, Jordi, Segrelles, Carmen, Garcia-Escudero, Ramon
Publicado 2021

Bcr/Abl Interferes with the Fanconi Anemia/BRCA Pathway: Implications in the Chromosomal Instability of Chronic Myeloid Leukemia Cells

por Valeri, Antonio, Alonso-Ferrero, Maria Eugenia, Río, Paula, Pujol, María Roser, Casado, José A., Pérez, Laura, Jacome, Ariana, Agirre, Xabier, Calasanz, Maria José, Hanenberg, Helmut, Surrallés, Jordi, Prosper, Felipe, Albella, Beatriz, Bueren, Juan A.
Publicado 2010

FANCA Gene Mutations in North African Fanconi Anemia Patients

por Ben Haj Ali, Abir, Messaoud, Olfa, Elouej, Sahar, Talmoudi, Faten, Ayed, Wiem, Mellouli, Fethi, Ouederni, Monia, Hadiji, Sondes, De Sandre-Giovannoli, Annachiara, Delague, Valérie, Lévy, Nicolas, Bogliolo, Massimo, Surrallés, Jordi, Abdelhak, Sonia, Amouri, Ahlem
Publicado 2021

Upregulation of NKG2D ligands impairs hematopoietic stem cell function in Fanconi anemia

por Casado, José A., Valeri, Antonio, Sanchez-Domínguez, Rebeca, Vela, Paula, López, Andrea, Navarro, Susana, Alberquilla, Omaira, Hanenberg, Helmut, Pujol, Roser, Segovia, José-Carlos, Minguillón, Jordi, Surrallés, Jordi, de Heredia, Cristina Díaz, Sevilla, Julián, Rio, Paula, Bueren, Juan A.
Publicado 2022

Clinical consequences of BRCA2 hypomorphism

por Castells-Roca, Laia, Gutiérrez-Enríquez, Sara, Bonache, Sandra, Bogliolo, Massimo, Carrasco, Estela, Aza-Carmona, Miriam, Montalban, Gemma, Muñoz-Subirana, Núria, Pujol, Roser, Cruz, Cristina, Llop-Guevara, Alba, Ramírez, María J., Saura, Cristina, Lasa, Adriana, Serra, Violeta, Diez, Orland, Balmaña, Judith, Surrallés, Jordi
Publicado 2021

Gene therapy restores the transcriptional program of hematopoietic stem cells in Fanconi anemia

por Lasaga, Miren, Río, Paula, Vilas-Zornoza, Amaia, Planell, Nuria, Navarro, Susana, Alignani, Diego, Fernández-Varas, Beatriz, Mouzo, Daniel, Zubicaray, Josune, Pujol, Roser M., Nicoletti, Eileen, Schwartz, Jonathan D., Sevilla, Julián, Ainciburi, Marina, Ullate-Agote, Asier, Surrallés, Jordi, Perona, Rosario, Sastre, Leandro, Prosper, Felipe, Gomez-Cabrero, David, Bueren, Juan A.
Publicado 2023

Targeted gene therapy and cell reprogramming in Fanconi anemia

por Rio, Paula, Baños, Rocio, Lombardo, Angelo, Quintana-Bustamante, Oscar, Alvarez, Lara, Garate, Zita, Genovese, Pietro, Almarza, Elena, Valeri, Antonio, Díez, Begoña, Navarro, Susana, Torres, Yaima, Trujillo, Juan P, Murillas, Rodolfo, Segovia, Jose C, Samper, Enrique, Surralles, Jordi, Gregory, Philip D, Holmes, Michael C, Naldini, Luigi, Bueren, Juan A
Publicado 2014