Advancements in DNA vaccine vectors, non-mechanical delivery methods, and molecular adjuvants to increase immunogenicity

por Suschak, John J., Williams, James A., Schmaljohn, Connie S.
Publicado 2017

Effects of ALT-801, a GLP-1 and glucagon receptor dual agonist, in a translational mouse model of non-alcoholic steatohepatitis

por Nestor, John J., Parkes, David, Feigh, Michael, Suschak, John J., Harris, M. Scott
Publicado 2022

A CCHFV DNA vaccine protects against heterologous challenge and establishes GP38 as immunorelevant in mice

por Suschak, John J., Golden, Joseph W., Fitzpatrick, Collin J., Shoemaker, Charles J., Badger, Catherine V., Schmaljohn, Connie S., Garrison, Aura R.
Publicado 2021

Induced protection from a CCHFV-M DNA vaccine requires CD8(+) T cells

por Golden, Joseph W., Fitzpatrick, Collin J., Suschak, John J., Clements, Tamara L., Ricks, Keersten M., Sanchez-Lockhart, Mariano, Garrison, Aura R.
Publicado 2023

Nanoplasmid Vectors Co-expressing Innate Immune Agonists Enhance DNA Vaccines for Venezuelan Equine Encephalitis Virus and Ebola Virus

por Suschak, John J., Dupuy, Lesley C., Shoemaker, Charles J., Six, Carolyn, Kwilas, Steven A., Spik, Kristin W., Williams, James A., Schmaljohn, Connie S.
Publicado 2020

An immunoinformatics-derived DNA vaccine encoding human class II T cell epitopes of Ebola virus, Sudan virus, and Venezuelan equine encephalitis virus is immunogenic in HLA transge...

por Bounds, Callie E., Terry, Frances E., Moise, Leonard, Hannaman, Drew, Martin, William D., De Groot, Anne S., Suschak, John J., Dupuy, Lesley C., Schmaljohn, Connie S.
Publicado 2017

A DNA vaccine targeting VEE virus delivered by needle-free jet-injection protects macaques against aerosol challenge

por Suschak, John J., Bixler, Sandra L., Badger, Catherine V., Spik, Kristin W., Kwilas, Steven A., Rossi, Franco D., Twenhafel, Nancy, Adams, Melissa L., Shoemaker, Charles J., Spiegel, Erin, Hooper, Jay W.
Publicado 2022

The role of vaccination route with an adenovirus-vectored vaccine in protection, viral control, and transmission in the SARS-CoV-2/K18-hACE2 mouse infection model

por Dickson, Alexandria, Geerling, Elizabeth, Stone, E. Taylor, Hassert, Mariah, Steffen, Tara L., Makkena, Taneesh, Smither, Madeleine, Schwetye, Katherine E., Zhang, Jianfeng, Georges, Bertrand, Roberts, M. Scot, Suschak, John J., Pinto, Amelia K., Brien, James D.
Publicado 2023

A DNA vaccine for Crimean-Congo hemorrhagic fever protects against disease and death in two lethal mouse models

por Garrison, Aura R., Shoemaker, Charles J., Golden, Joseph W., Fitzpatrick, Collin J., Suschak, John J., Richards, Michelle J., Badger, Catherine V., Six, Carolyn M., Martin, Jacqueline D., Hannaman, Drew, Zivcec, Marko, Bergeron, Eric, Koehler, Jeffrey W., Schmaljohn, Connie S.
Publicado 2017

A single intranasal administration of AdCOVID protects against SARS-CoV-2 infection in the upper and lower respiratory tracts

por Schultz, Michael D., Suschak, John J., Botta, Davide, Silva-Sanchez, Aaron, King, R. Glenn, Detchemendy, Thomas W., Meshram, Chetan D., Foote, Jeremy B., Zhou, Fen, Tipper, Jennifer L., Zhang, Jianfeng, Harrod, Kevin S., Leal, Sixto M., Randall, Troy D., Roberts, M. Scot, Georges, Bertrand, Lund, Frances E.
Publicado 2022

Single-Dose Intranasal Administration of AdCOVID Elicits Systemic and Mucosal Immunity against SARS-CoV-2 and Fully Protects Mice from Lethal Challenge

por King, R. Glenn, Silva-Sanchez, Aaron, Peel, Jessica N., Botta, Davide, Dickson, Alexandria M., Pinto, Amelia K., Meza-Perez, Selene, Allie, S. Rameeza, Schultz, Michael D., Liu, Mingyong, Bradley, John E., Qiu, Shihong, Yang, Guang, Zhou, Fen, Zumaquero, Esther, Simpler, Thomas S., Mousseau, Betty, Killian, John T., Dean, Brittany, Shang, Qiao, Tipper, Jennifer L., Risley, Christopher A., Harrod, Kevin S., Feng, Tsungwei, Lee, Young, Shiberu, Bethlehem, Krishnan, Vyjayanthi, Peguillet, Isabelle, Zhang, Jianfeng, Green, Todd J., Randall, Troy D., Suschak, John J., Georges, Bertrand, Brien, James D., Lund, Frances E., Roberts, M. Scot
Publicado 2021