Bridging of DNA breaks activates PARP2–HPF1 to modify chromatin

por Bilokapic, Silvija, Suskiewicz, Marcin J., Ahel, Ivan, Halic, Mario
Publicado 2020

The potential of PARP inhibitors in targeted cancer therapy and immunotherapy

por Hunia, Jaromir, Gawalski, Karol, Szredzka, Aleksandra, Suskiewicz, Marcin J., Nowis, Dominika
Publicado 2022

McsB forms a gated kinase chamber to mark aberrant bacterial proteins for degradation

por Hajdusits, Bence, Suskiewicz, Marcin J, Hundt, Nikolas, Meinhart, Anton, Kurzbauer, Robert, Leodolter, Julia, Kukura, Philipp, Clausen, Tim
Publicado 2021

Serine ADP-ribosylation in Drosophila provides insights into the evolution of reversible ADP-ribosylation signalling

por Fontana, Pietro, Buch-Larsen, Sara C., Suyari, Osamu, Smith, Rebecca, Suskiewicz, Marcin J., Schützenhofer, Kira, Ariza, Antonio, Rack, Johannes Gregor Matthias, Nielsen, Michael L., Ahel, Ivan
Publicado 2023

HPF1 completes the PARP active site for DNA damage-induced ADP-ribosylation

por Suskiewicz, Marcin J., Zobel, Florian, Ogden, Tom E. H., Fontana, Pietro, Ariza, Antonio, Yang, Ji-Chun, Zhu, Kang, Bracken, Lily, Hawthorne, William J., Ahel, Dragana, Neuhaus, David, Ahel, Ivan
Publicado 2020

Serine-linked PARP1 auto-modification controls PARP inhibitor response

por Prokhorova, Evgeniia, Zobel, Florian, Smith, Rebecca, Zentout, Siham, Gibbs-Seymour, Ian, Schützenhofer, Kira, Peters, Alessandra, Groslambert, Joséphine, Zorzini, Valentina, Agnew, Thomas, Brognard, John, Nielsen, Michael L., Ahel, Dragana, Huet, Sébastien, Suskiewicz, Marcin J., Ahel, Ivan
Publicado 2021

Updated protein domain annotation of the PARP protein family sheds new light on biological function

por Suskiewicz, Marcin J, Munnur, Deeksha, Strømland, Øyvind, Yang, Ji-Chun, Easton, Laura E, Chatrin, Chatrin, Zhu, Kang, Baretić, Domagoj, Goffinont, Stéphane, Schuller, Marion, Wu, Wing-Fung, Elkins, Jonathan M, Ahel, Dragana, Sanyal, Sumana, Neuhaus, David, Ahel, Ivan
Publicado 2023

Unrestrained poly-ADP-ribosylation provides insights into chromatin regulation and human disease

por Prokhorova, Evgeniia, Agnew, Thomas, Wondisford, Anne R., Tellier, Michael, Kaminski, Nicole, Beijer, Danique, Holder, James, Groslambert, Josephine, Suskiewicz, Marcin J., Zhu, Kang, Reber, Julia M., Krassnig, Sarah C., Palazzo, Luca, Murphy, Shona, Nielsen, Michael L., Mangerich, Aswin, Ahel, Dragana, Baets, Jonathan, O’Sullivan, Roderick J., Ahel, Ivan
Publicado 2021