Excess exogenous pyruvate inhibits lactate dehydrogenase activity in live cells in an MCT1-dependent manner

por Rao, Yi, Gammon, Seth T., Sutton, Margie N., Zacharias, Niki M., Bhattacharya, Pratip, Piwnica-Worms, David
Publicado 2021

Amino Acid Deprivation-Induced Autophagy Requires Upregulation of DIRAS3 through Reduction of E2F1 and E2F4 Transcriptional Repression

por Sutton, Margie N., Huang, Gilbert Y., Zhou, Jinhua, Mao, Weiqun, Langley, Robert, Lu, Zhen, Bast, Robert C.
Publicado 2019

Tumor necrosis factor-α and interferon-γ stimulate MUC16 (CA125) expression in breast, endometrial and ovarian cancers through NFκB

por Morgado, Micaela, Sutton, Margie N., Simmons, Mary, Warren, Curtis R., Lu, Zhen, Constantinou, Pamela E., Liu, Jinsong, Francis, Lewis LW., Conlan, R. Steven, Bast, Robert C., Carson, Daniel D.
Publicado 2016

Induction of autophagy by ARHI (DIRAS3) alters fundamental metabolic pathways in ovarian cancer models

por Ornelas, Argentina, McCullough, Christopher R., Lu, Zhen, Zacharias, Niki M., Kelderhouse, Lindsay E., Gray, Joshua, Yang, Hailing, Engel, Brian J., Wang, Yan, Mao, Weiqun, Sutton, Margie N., Bhattacharya, Pratip K., Bast, Robert C., Millward, Steven W.
Publicado 2016

Gender Differences in a Mouse Model of Hepatocellular Carcinoma Revealed Using Multi-Modal Imaging

por Engel, Brian J., Paolillo, Vincenzo, Uddin, Md. Nasir, Gonzales, Kristyn A., McGinnis, Kathryn M., Sutton, Margie N., Patnana, Madhavi, Grindel, Brian J., Gores, Gregory J., Piwnica-Worms, David, Beretta, Laura, Pisaneschi, Federica, Gammon, Seth T., Millward, Steven W.
Publicado 2023

DIRAS3-Derived Peptide Inhibits Autophagy in Ovarian Cancer Cells by Binding to Beclin1

por Sutton, Margie N., Huang, Gilbert Y., Liang, Xiaowen, Sharma, Rajesh, Reger, Albert S., Mao, Weiqun, Pang, Lan, Rask, Philip J., Lee, Kwangkook, Gray, Joshua P., Hurwitz, Amy M., Palzkill, Timothy, Millward, Steven W., Kim, Choel, Lu, Zhen, Bast, Robert C.
Publicado 2019

Directed evolution of cyclic peptides for inhibition of autophagy

por Gray, Joshua P., Uddin, Md. Nasir, Chaudhari, Rajan, Sutton, Margie N., Yang, Hailing, Rask, Philip, Locke, Hannah, Engel, Brian J., Batistatou, Nefeli, Wang, Jing, Grindel, Brian J., Bhattacharya, Pratip, Gammon, Seth T., Zhang, Shuxing, Piwnica-Worms, David, Kritzer, Joshua A., Lu, Zhen, Bast, Robert C., Millward, Steven W.
Publicado 2021