Odanacatib, a Cathepsin K Cysteine Protease Inhibitor, Kills Hookworm In Vivo

por Vermeire, Jon J., Suzuki, Brian M., Caffrey, Conor R.
Publicado 2016

Anti-Schistosomal Activity of Cinnamic Acid Esters: Eugenyl and Thymyl Cinnamate Induce Cytoplasmic Vacuoles and Death in Schistosomula of Schistosoma mansoni

por Glaser, Jan, Schurigt, Uta, Suzuki, Brian M., Caffrey, Conor R., Holzgrabe, Ulrike
Publicado 2015

Effect of Phenotypic Screening of Extracts and Fractions of Erythrophleum ivorense Leaf and Stem Bark on Immature and Adult Stages of Schistosoma mansoni

por Kyere-Davies, Gertrude, Agyare, Christian, Boakye, Yaw Duah, Suzuki, Brian M., Caffrey, Conor R.
Publicado 2018

Chemical and Genetic Validation of the Statin Drug Target to Treat the Helminth Disease, Schistosomiasis

por Rojo-Arreola, Liliana, Long, Thavy, Asarnow, Dan, Suzuki, Brian M., Singh, Rahul, Caffrey, Conor R.
Publicado 2014

A multi-dimensional, time-lapse, high content screening platform applied to schistosomiasis drug discovery

por Chen, Steven, Suzuki, Brian M., Dohrmann, Jakob, Singh, Rahul, Arkin, Michelle R., Caffrey, Conor R.
Publicado 2020

Cysteine and Aspartyl Proteases Contribute to Protein Digestion in the Gut of Freshwater Planaria

por Goupil, Louise S., Ivry, Sam L., Hsieh, Ivy, Suzuki, Brian M., Craik, Charles S., O’Donoghue, Anthony J., McKerrow, James H.
Publicado 2016

Quantification and clustering of phenotypic screening data using time-series analysis for chemotherapy of schistosomiasis

por Lee, Hyokyeong, Moody-Davis, Asher, Saha, Utsab, Suzuki, Brian M, Asarnow, Daniel, Chen, Steven, Arkin, Michelle, Caffrey, Conor R, Singh, Rahul
Publicado 2012

Bioactivity of Farnesyltransferase Inhibitors Against Entamoeba histolytica and Schistosoma mansoni

por Probst, Alexandra, Nguyen, Thi N., El-Sakkary, Nelly, Skinner, Danielle, Suzuki, Brian M., Buckner, Frederick S., Gelb, Michael H., Caffrey, Conor R., Debnath, Anjan
Publicado 2019

Evaluation of the CCA Immuno-Chromatographic Test to Diagnose Schistosoma mansoni in Minas Gerais State, Brazil

por Silveira, Alda Maria Soares, Costa, Emanuele Gama Dutra, Ray, Debalina, Suzuki, Brian M., Hsieh, Michael H., Fraga, Lucia Alves de Oliveira, Caffrey, Conor R.
Publicado 2016

TPT sulfonate, a single, oral dose schistosomicidal prodrug: In vivo efficacy, disposition and metabolic profiling

por Wolfe, Alan R., Neitz, R. Jeffrey, Burlingame, Mark, Suzuki, Brian M., Lim, KC, Scheideler, Mark, Nelson, David L., Benet, Leslie Z., Caffrey, Conor R.
Publicado 2018

Multi-center screening of the Pathogen Box collection for schistosomiasis drug discovery

por Maccesi, Martina, Aguiar, Pedro H. N., Pasche, Valérian, Padilla, Melody, Suzuki, Brian M., Montefusco, Sandro, Abagyan, Ruben, Keiser, Jennifer, Mourão, Marina M., Caffrey, Conor R.
Publicado 2019

Structure-Bioactivity Relationship for Benzimidazole Thiophene Inhibitors of Polo-Like Kinase 1 (PLK1), a Potential Drug Target in Schistosoma mansoni

por Long, Thavy, Neitz, R. Jeffrey, Beasley, Rachel, Kalyanaraman, Chakrapani, Suzuki, Brian M., Jacobson, Matthew P., Dissous, Colette, McKerrow, James H., Drewry, David H., Zuercher, William J., Singh, Rahul, Caffrey, Conor R.
Publicado 2016

Sertraline, Paroxetine, and Chlorpromazine Are Rapidly Acting Anthelmintic Drugs Capable of Clinical Repurposing

por Weeks, Janis C., Roberts, William M., Leasure, Caitlyn, Suzuki, Brian M., Robinson, Kristin J., Currey, Heather, Wangchuk, Phurpa, Eichenberger, Ramon M., Saxton, Aleen D., Bird, Thomas D., Kraemer, Brian C., Loukas, Alex, Hawdon, John M., Caffrey, Conor R., Liachko, Nicole F.
Publicado 2018

Macrofilaricidal Benzimidazole–Benzoxaborole Hybrids as an Approach to the Treatment of River Blindness: Part 2. Ketone Linked Analogs

por Carter, David S., Jacobs, Robert T., Freund, Yvonne R., Berry, Pamela W., Akama, Tsutomu, Easom, Eric E., Lunde, Christopher S., Rock, Fernando, Stefanakis, Rianna, McKerrow, James, Fischer, Chelsea, Bulman, Christina A., Lim, Kee Chong, Suzuki, Brian M., Tricoche, Nancy, Sakanari, Judy A., Lustigman, Sara, Plattner, Jacob J.
Publicado 2019

Macrofilaricidal Benzimidazole–Benzoxaborole Hybrids as an Approach to the Treatment of River Blindness: Part 1. Amide Linked Analogs

por Akama, Tsutomu, Freund, Yvonne R., Berry, Pamela W., Carter, David S., Easom, Eric E., Jarnagin, Kurt, Lunde, Christopher S., Plattner, Jacob J., Rock, Fernando, Stefanakis, Rianna, Fischer, Chelsea, Bulman, Christina A., Lim, Kee Chong, Suzuki, Brian M., Tricoche, Nancy, Mansour, Abdelmoneim, DiCosty, Utami, McCall, Scott, Carson, Ben, McCall, John W., McKerrow, James, Hübner, Marc P., Specht, Sabine, Hoerauf, Achim, Lustigman, Sara, Sakanari, Judy A., Jacobs, Robert T.
Publicado 2019

Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond

por Van Voorhis, Wesley C., Adams, John H., Adelfio, Roberto, Ahyong, Vida, Akabas, Myles H., Alano, Pietro, Alday, Aintzane, Alemán Resto, Yesmalie, Alsibaee, Aishah, Alzualde, Ainhoa, Andrews, Katherine T., Avery, Simon V., Avery, Vicky M., Ayong, Lawrence, Baker, Mark, Baker, Stephen, Ben Mamoun, Choukri, Bhatia, Sangeeta, Bickle, Quentin, Bounaadja, Lotfi, Bowling, Tana, Bosch, Jürgen, Boucher, Lauren E., Boyom, Fabrice F., Brea, Jose, Brennan, Marian, Burton, Audrey, Caffrey, Conor R., Camarda, Grazia, Carrasquilla, Manuela, Carter, Dee, Belen Cassera, Maria, Chih-Chien Cheng, Ken, Chindaudomsate, Worathad, Chubb, Anthony, Colon, Beatrice L., Colón-López, Daisy D., Corbett, Yolanda, Crowther, Gregory J., Cowan, Noemi, D’Alessandro, Sarah, Le Dang, Na, Delves, Michael, DeRisi, Joseph L., Du, Alan Y., Duffy, Sandra, Abd El-Salam El-Sayed, Shimaa, Ferdig, Michael T., Fernández Robledo, José A., Fidock, David A., Florent, Isabelle, Fokou, Patrick V. T., Galstian, Ani, Gamo, Francisco Javier, Gokool, Suzanne, Gold, Ben, Golub, Todd, Goldgof, Gregory M., Guha, Rajarshi, Guiguemde, W. Armand, Gural, Nil, Guy, R. Kiplin, Hansen, Michael A. E., Hanson, Kirsten K., Hemphill, Andrew, Hooft van Huijsduijnen, Rob, Horii, Takaaki, Horrocks, Paul, Hughes, Tyler B., Huston, Christopher, Igarashi, Ikuo, Ingram-Sieber, Katrin, Itoe, Maurice A., Jadhav, Ajit, Naranuntarat Jensen, Amornrat, Jensen, Laran T., Jiang, Rays H. Y., Kaiser, Annette, Keiser, Jennifer, Ketas, Thomas, Kicka, Sebastien, Kim, Sunyoung, Kirk, Kiaran, Kumar, Vidya P., Kyle, Dennis E., Lafuente, Maria Jose, Landfear, Scott, Lee, Nathan, Lee, Sukjun, Lehane, Adele M., Li, Fengwu, Little, David, Liu, Liqiong, Llinás, Manuel, Loza, Maria I., Lubar, Aristea, Lucantoni, Leonardo, Lucet, Isabelle, Maes, Louis, Mancama, Dalu, Mansour, Nuha R., March, Sandra, McGowan, Sheena, Medina Vera, Iset, Meister, Stephan, Mercer, Luke, Mestres, Jordi, Mfopa, Alvine N., Misra, Raj N., Moon, Seunghyun, Moore, John P., Morais Rodrigues da Costa, Francielly, Müller, Joachim, Muriana, Arantza, Nakazawa Hewitt, Stephen, Nare, Bakela, Nathan, Carl, Narraidoo, Nathalie, Nawaratna, Sujeevi, Ojo, Kayode K., Ortiz, Diana, Panic, Gordana, Papadatos, George, Parapini, Silvia, Patra, Kailash, Pham, Ngoc, Prats, Sarah, Plouffe, David M., Poulsen, Sally-Ann, Pradhan, Anupam, Quevedo, Celia, Quinn, Ronald J., Rice, Christopher A., Abdo Rizk, Mohamed, Ruecker, Andrea, St. Onge, Robert, Salgado Ferreira, Rafaela, Samra, Jasmeet, Robinett, Natalie G., Schlecht, Ulrich, Schmitt, Marjorie, Silva Villela, Filipe, Silvestrini, Francesco, Sinden, Robert, Smith, Dennis A., Soldati, Thierry, Spitzmüller, Andreas, Stamm, Serge Maximilian, Sullivan, David J., Sullivan, William, Suresh, Sundari, Suzuki, Brian M., Suzuki, Yo, Swamidass, S. Joshua, Taramelli, Donatella, Tchokouaha, Lauve R. Y., Theron, Anjo, Thomas, David, Tonissen, Kathryn F., Townson, Simon, Tripathi, Abhai K., Trofimov, Valentin, Udenze, Kenneth O., Ullah, Imran, Vallieres, Cindy, Vigil, Edgar, Vinetz, Joseph M., Voong Vinh, Phat, Vu, Hoan, Watanabe, Nao-aki, Weatherby, Kate, White, Pamela M., Wilks, Andrew F., Winzeler, Elizabeth A., Wojcik, Edward, Wree, Melanie, Wu, Wesley, Yokoyama, Naoaki, Zollo, Paul H. A., Abla, Nada, Blasco, Benjamin, Burrows, Jeremy, Laleu, Benoît, Leroy, Didier, Spangenberg, Thomas, Wells, Timothy, Willis, Paul A.
Publicado 2016