Modulators of γ-Secretase Activity Can Facilitate the Toxic Side-Effects and Pathogenesis of Alzheimer's Disease

por Svedružić, Željko M., Popović, Katarina, Šendula-Jengić, Vesna
Publicado 2013

Correction: Modulators of γ-Secretase Activity Can Facilitate the Toxic Side-Effects and Pathogenesis of Alzheimer's Disease

por Svedružić, Željko M., Popović, Katarina, Šendula-Jengić, Vesna
Publicado 2013

The Binding of Different Substrate Molecules at the Docking Site and the Active Site of γ-Secretase Can Trigger Toxic Events in Sporadic and Familial Alzheimer’s Disease

por Svedružić, Željko M., Šendula Jengić, Vesna, Ostojić, Lucija
Publicado 2023

In silico design of the first DNA-independent mechanism-based inhibitor of mammalian DNA methyltransferase Dnmt1

por Miletić, Vedran, Odorčić, Ivica, Nikolić, Patrik, Svedružić, Željko M.
Publicado 2017

Structural Analysis of the Simultaneous Activation and Inhibition of γ-Secretase Activity in the Development of Drugs for Alzheimer’s Disease

por Svedružić, Željko M., Vrbnjak, Katarina, Martinović, Manuel, Miletić, Vedran
Publicado 2021

Modulation of γ-Secretase Activity by Multiple Enzyme-Substrate Interactions: Implications in Pathogenesis of Alzheimer's Disease

por Svedružić, Željko M., Popović, Katarina, Smoljan, Ivana, Šendula-Jengić, Vesna
Publicado 2012

Substrate Channeling via a Transient Protein-Protein Complex: The case of D-Glyceraldehyde-3-Phosphate Dehydrogenase and L-Lactate Dehydrogenase

por Svedružić, Željko M., Odorčić, Ivica, Chang, Christopher H., Svedružić, Draženka
Publicado 2020

Prion Protein Octarepeat Domain Forms Transient β-Sheet Structures upon Residue-Specific Binding to Cu(II) and Zn(II) Ions

por Gielnik, Maciej, Szymańska, Aneta, Dong, Xiaolin, Jarvet, Jüri, Svedružić, Željko M., Gräslund, Astrid, Kozak, Maciej, Wärmländer, Sebastian K. T. S.
Publicado 2023

Co-Aggregation of S100A9 with DOPA and Cyclen-Based Compounds Manifested in Amyloid Fibril Thickening without Altering Rates of Self-Assembly

por Arabuli, Lili, Iashchishyn, Igor A., Romanova, Nina V., Musteikyte, Greta, Smirnovas, Vytautas, Chaudhary, Himanshu, Svedružić, Željko M., Morozova-Roche, Ludmilla A.
Publicado 2021

Polyoxometalates as Effective Nano-inhibitors of Amyloid Aggregation of Pro-inflammatory S100A9 Protein Involved in Neurodegenerative Diseases

por Chaudhary, Himanshu, Iashchishyn, Igor A., Romanova, Nina V., Rambaran, Mark A., Musteikyte, Greta, Smirnovas, Vytautas, Holmboe, Michael, Ohlin, C. André, Svedružić, Željko M., Morozova-Roche, Ludmilla A.
Publicado 2021

Natural Compound from Olive Oil Inhibits S100A9 Amyloid Formation and Cytotoxicity: Implications for Preventing Alzheimer’s Disease

por Leri, Manuela, Chaudhary, Himanshu, Iashchishyn, Igor A., Pansieri, Jonathan, Svedružić, Željko M., Gómez Alcalde, Silvia, Musteikyte, Greta, Smirnovas, Vytautas, Stefani, Massimo, Bucciantini, Monica, Morozova-Roche, Ludmilla A.
Publicado 2021