Exploring the therapeutic potential of modern and ancestral phenylalanine/tyrosine ammonia-lyases as supplementary treatment of hereditary tyrosinemia

por Hendrikse, Natalie M., Holmberg Larsson, Albin, Svensson Gelius, Stefan, Kuprin, Sergei, Nordling, Erik, Syrén, Per-Olof
Publicado 2020

Intravenous delivery of a chemically modified sulfamidase efficiently reduces heparan sulfate storage and brain pathology in mucopolysaccharidosis IIIA mice

por Gustavsson, Susanne, Ohlin Sjöström, Elisabet, Tjernberg, Agneta, Janson, Juliette, Westermark, Ulrica, Andersson, Tommy, Makower, Åsa, Arnelöf, Erik, Andersson, Gudrun, Svartengren, Jan, Ekholm, Carina, Svensson Gelius, Stefan
Publicado 2019

Ancestral lysosomal enzymes with increased activity harbor therapeutic potential for treatment of Hunter syndrome

por Hendrikse, Natalie M., Sandegren, Anna, Andersson, Tommy, Blomqvist, Jenny, Makower, Åsa, Possner, Dominik, Su, Chao, Thalén, Niklas, Tjernberg, Agneta, Westermark, Ulrica, Rockberg, Johan, Svensson Gelius, Stefan, Syrén, Per-Olof, Nordling, Erik
Publicado 2021