The kinase Isr1 negatively regulates hexosamine biosynthesis in S. cerevisiae

por Alme, Emma B., Stevenson, Erica, Krogan, Nevan J., Swaney, Danielle L., Toczyski, David P.
Publicado 2020

Cross-family small GTPase ubiquitination by the intracellular pathogen Legionella pneumophila

por Steinbach, Adriana M., Bhadkamkar, Varun L., Jimenez-Morales, David, Stevenson, Erica, Jang, Gwendolyn M., Krogan, Nevan J., Swaney, Danielle L., Mukherjee, Shaeri
Publicado 2023

TCO, a Putative Transcriptional Regulator in Arabidopsis, Is a Target of the Protein Kinase CK2

por Weinman, Laina M., Running, Katherine L. D., Carey, Nicholas S., Stevenson, Erica J., Swaney, Danielle L., Chow, Brenda Y., Krogan, Nevan J., Krogan, Naden T.
Publicado 2018

Neuronal Apolipoprotein E4 Expression Results in Proteome-Wide Alterations and Compromises Bioenergetic Capacity by Disrupting Mitochondrial Function

por Orr, Adam L., Kim, Chaeyoung, Jimenez-Morales, David, Newton, Billy W., Johnson, Jeffrey R., Krogan, Nevan J., Swaney, Danielle L., Mahley, Robert W.
Publicado 2019

Sympathetic inputs regulate adaptive thermogenesis in brown adipose tissue through cAMP-Salt inducible kinase axis

por Paulo, Esther, Wu, Dongmei, Wang, Yangmeng, Zhang, Yun, Wu, Yixuan, Swaney, Danielle L., Soucheray, Margaret, Jimenez-Morales, David, Chawla, Ajay, Krogan, Nevan J., Wang, Biao
Publicado 2018

Lysosomal proteomics reveals mechanisms of neuronal apoE4associated lysosomal dysfunction

por Krogsaeter, Einar K., McKetney, Justin, Marquez, Angelica, Cakir, Zeynep, Stevenson, Erica, Jang, Gwendolyn M., Rao, Antara, Zhou, Anton, Huang, Yadong, Krogan, Nevan J., Swaney, Danielle L.
Publicado 2023

Next-generation proteomics for quantitative Jumbophage-bacteria interaction mapping

por Fossati, Andrea, Mozumdar, Deepto, Kokontis, Claire, Mèndez-Moran, Melissa, Nieweglowska, Eliza, Pelin, Adrian, Li, Yuping, Guo, Baron, Krogan, Nevan J., Agard, David A., Bondy-Denomy, Joseph, Swaney, Danielle L.
Publicado 2023

Merlin(S13) phosphorylation controls meningioma Wnt signaling and magnetic resonance imaging features

por Eaton, Charlotte, Avalos, Lauro, Liu, S. John, Casey-clyde, Tim, Bisignano, Paola, Lucas, Calixto-Hope, Stevenson, Erica, Choudhury, Abrar, Vasudevan, Harish, Magill, Stephen, Krogan, Nevan, Villanueva-Meyer, Javier, Swaney, Danielle, Raleigh, David
Publicado 2023

A ciliopathy complex builds distal appendages to initiate ciliogenesis

por Kumar, Dhivya, Rains, Addison, Herranz-Pérez, Vicente, Lu, Quanlong, Shi, Xiaoyu, Swaney, Danielle L., Stevenson, Erica, Krogan, Nevan J., Huang, Bo, Westlake, Christopher, Garcia-Verdugo, Jose Manuel, Yoder, Bradley K., Reiter, Jeremy F.
Publicado 2021

CRISPR screens in iPSC-derived neurons reveal principles of tau proteostasis

por Samelson, Avi J., Ariqat, Nabeela, McKetney, Justin, Rohanitazangi, Gita, Bravo, Celeste Parra, Goodness, Darrin, Tian, Ruilin, Grosjean, Parker, Abskharon, Romany, Eisenberg, David, Kanaan, Nicholas M., Gan, Li, Condello, Carlo, Swaney, Danielle L., Kampmann, Martin
Publicado 2023

Dynamic post-translational modification profiling of Mycobacterium tuberculosis-infected primary macrophages

por Budzik, Jonathan M, Swaney, Danielle L, Jimenez-Morales, David, Johnson, Jeffrey R, Garelis, Nicholas E, Repasy, Teresa, Roberts, Allison W, Popov, Lauren M, Parry, Trevor J, Pratt, Dexter, Ideker, Trey, Krogan, Nevan J, Cox, Jeffery S
Publicado 2020

The functional landscape of the human phosphoproteome

por Ochoa, David, Jarnuczak, Andrew F., Viéitez, Cristina, Gehre, Maja, Soucheray, Margaret, Mateus, André, Kleefeldt, Askar A., Hill, Anthony, Garcia-Alonso, Luz, Stein, Frank, Krogan, Nevan J., Savitski, Mikhail M., Swaney, Danielle L., Vizcaíno, Juan A., Noh, Kyung-Min, Beltrao, Pedro
Publicado 2019

Quantitative Proteomic Analysis Reveals apoE4-Dependent Phosphorylation of the Actin-Regulating Protein VASP

por Cakir, Zeynep, Lord, Samuel J., Zhou, Yuan, Jang, Gwendolyn M., Polacco, Benjamin J., Eckhardt, Manon, Jimenez-Morales, David, Newton, Billy W., Orr, Adam L., Johnson, Jeffrey R., da Cruz, Alexandre, Mullins, R. Dyche, Krogan, Nevan J., Mahley, Robert W., Swaney, Danielle L.
Publicado 2023

Reduced endosomal microautophagy activity in aging associates with enhanced exocyst‐mediated protein secretion

por Krause, Gregory J., Diaz, Antonio, Jafari, Maryam, Khawaja, Rabia R., Agullo‐Pascual, Esperanza, Santiago‐Fernández, Olaya, Richards, Alicia L., Chen, Kuei‐Ho, Dmitriev, Phillip, Sun, Yan, See, Stephanie K., Abdelmohsen, Kotb, Mazan‐Mamczarz, Krystyna, Krogan, Nevan J., Gorospe, Myriam, Swaney, Danielle L., Sidoli, Simone, Bravo‐Cordero, Jose Javier, Kampmann, Martin, Cuervo, Ana Maria
Publicado 2022

Oncogenic PKA signaling increases c-MYC protein expression through multiple targetable mechanisms

por Chan, Gary KL, Maisel, Samantha, Hwang, Yeonjoo C, Pascual, Bryan C, Wolber, Rebecca RB, Vu, Phuong, Patra, Krushna C, Bouhaddou, Mehdi, Kenerson, Heidi L, Lim, Huat C, Long, Donald, Yeung, Raymond S, Sethupathy, Praveen, Swaney, Danielle L, Krogan, Nevan J, Turnham, Rigney E, Riehle, Kimberly J, Scott, John D, Bardeesy, Nabeel, Gordan, John D
Publicado 2023

Caveolin-1 and Sox-2 are predictive biomarkers of cetuximab response in head and neck cancer

por Bouhaddou, Mehdi, Lee, Rex H., Li, Hua, Bhola, Neil E., O’Keefe, Rachel A., Naser, Mohammad, Zhu, Tian Ran, Nwachuku, Kelechi, Duvvuri, Umamaheswar, Olshen, Adam B., Roy, Ritu, Hechmer, Aaron, Bolen, Jennifer, Keysar, Stephen B., Jimeno, Antonio, Mills, Gordon B., Vandenberg, Scott, Swaney, Danielle L., Johnson, Daniel E., Krogan, Nevan J., Grandis, Jennifer R.
Publicado 2021

High-throughput chemogenetic drug screening reveals PKC-RhoA/PKN as a targetable signaling vulnerability in GNAQ-driven uveal melanoma

por Arang, Nadia, Lubrano, Simone, Ceribelli, Michele, Rigiracciolo, Damiano C., Saddawi-Konefka, Robert, Faraji, Farhoud, Ramirez, Sydney I., Kim, Daehwan, Tosto, Frances A., Stevenson, Erica, Zhou, Yuan, Wang, Zhiyong, Bogomolovas, Julius, Molinolo, Alfredo A., Swaney, Danielle L., Krogan, Nevan J., Yang, Jing, Coma, Silvia, Pachter, Jonathan A., Aplin, Andrew E., Alessi, Dario R., Thomas, Craig J., Gutkind, J. Silvio
Publicado 2023

Host-directed therapies against early-lineage SARS-CoV-2 retain efficacy against B.1.1.7 variant

por Reuschl, Ann-Kathrin, Thorne, Lucy G., Zuliani-Alvarez, Lorena, Bouhaddou, Mehdi, Obernier, Kirsten, Hiatt, Joseph, Soucheray, Margaret, Turner, Jane, Fabius, Jacqueline M., Nguyen, Gina T., Swaney, Danielle L., Rosales, Romel, White, Kris M., Avilés, Pablo, Kirby, Ilsa T., Melnyk, James E., Shi, Ying, Zhang, Ziyang, Shokat, Kevan M., García-Sastre, Adolfo, Jolly, Clare, Towers, Gregory J., Krogan, Nevan J.
Publicado 2021

The E3 ligase TRIM1 ubiquitinates LRRK2 and controls its localization, degradation, and toxicity

por Stormo, Adrienne E.D., Shavarebi, Farbod, FitzGibbon, Molly, Earley, Elizabeth M., Ahrendt, Hannah, Lum, Lotus S., Verschueren, Erik, Swaney, Danielle L., Skibinski, Gaia, Ravisankar, Abinaya, van Haren, Jeffrey, Davis, Emily J., Johnson, Jeffrey R., Von Dollen, John, Balen, Carson, Porath, Jacob, Crosio, Claudia, Mirescu, Christian, Iaccarino, Ciro, Dauer, William T., Nichols, R. Jeremy, Wittmann, Torsten, Cox, Timothy C., Finkbeiner, Steve, Krogan, Nevan J., Oakes, Scott A., Hiniker, Annie
Publicado 2022

The microenvironment dictates glycocalyx construction and immune surveillance

por Tharp, Kevin M., Park, Sangwoo, Timblin, Greg A., Richards, Alicia L., Berg, Jordan A., Twells, Nicholas M., Riley, Nicholas M., Peltan, Egan L., Shon, D. Judy, Stevenson, Erica, Tsui, Kimberly, Palomba, Francesco, Lefebvre, Austin E. Y. T., Soens, Ross W., Ayad, Nadia M.E., Hoeve-Scott, Johanna ten, Healy, Kevin, Digman, Michelle, Dillin, Andrew, Bertozzi, Carolyn R., Swaney, Danielle L., Mahal, Lara K., Cantor, Jason R., Paszek, Matthew J., Weaver, Valerie M.
Publicado 2023