A novel landscape of nuclear human CDK2 substrates revealed by in situ phosphorylation

por Chi, Yong, Carter, John H., Swanger, Jherek, Mazin, Alexander V., Moritz, Robert L., Clurman, Bruce E.
Publicado 2020

Two diphosphorylated degrons control c-Myc degradation by the Fbw7 tumor suppressor

por Welcker, Markus, Wang, Baiyun, Rusnac, Domniţa-Valeria, Hussaini, Yasser, Swanger, Jherek, Zheng, Ning, Clurman, Bruce E.
Publicado 2022

Fbw7 dimerization determines the specificity and robustness of substrate degradation

por Welcker, Markus, Larimore, Elizabeth A., Swanger, Jherek, Bengoechea-Alonso, Maria T., Grim, Jonathan E., Ericsson, Johan, Zheng, Ning, Clurman, Bruce E.
Publicado 2013

Isoform- and cell cycle–dependent substrate degradation by the Fbw7 ubiquitin ligase

por Grim, Jonathan E., Gustafson, Michael P., Hirata, Roli K., Hagar, Amanda C., Swanger, Jherek, Welcker, Markus, Hwang, Harry C., Ericsson, Johan, Russell, David W., Clurman, Bruce E.
Publicado 2008

Global and context-specific transcriptional consequences of oncogenic Fbw7 mutations

por Thirimanne, H Nayanga, Wu, Feinan, Janssens, Derek H, Swanger, Jherek, Diab, Ahmed, Feldman, Heather M, Amezquita, Robert A, Gottardo, Raphael, Paddison, Patrick J, Henikoff, Steven, Clurman, Bruce E
Publicado 2022